| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5ZJ41 | 281 | MARH5_CHICK E3 ubiquitin-protein ligase MARCH... | 79 | 0.000004 | 50.8 | 35 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB. | 2 | P27426 | 285 | VIE1_BHV4D Probable E3 ubiquitin-protein liga... | 118 | 0.000004 | 50.8 | 31 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q9P2E8 | 410 | MARH4_HUMAN E3 ubiquitin-protein ligase MARCH... | 127 | 0.000004 | 51.2 | 30 | 43 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 4 | Q80TE3 | 409 | MARH4_MOUSE E3 ubiquitin-protein ligase MARCH... | 127 | 0.000005 | 50.8 | 30 | 43 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 5 | A6P320 | 398 | MARHB_RAT E3 ubiquitin-protein ligase MARCH11... | 124 | 0.000006 | 50.8 | 30 | 44 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 6 | Q8CBH7 | 400 | MARHB_MOUSE E3 ubiquitin-protein ligase MARCH... | 124 | 0.000006 | 50.8 | 30 | 44 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 7 | A6NNE9 | 402 | MARHB_HUMAN E3 ubiquitin-protein ligase MARCH... | 124 | 0.00001 | 49.7 | 30 | 44 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 8 | Q0P496 | 421 | MARH4_DANRE E3 ubiquitin-protein ligase MARCH... | 127 | 0.00001 | 49.7 | 30 | 43 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 9 | Q6GM44 | 283 | MARH5_XENLA E3 ubiquitin-protein ligase MARCH... | 66 | 0.00002 | 48.5 | 36 | 50 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB. | 10 | Q3KNM2 | 278 | MARH5_MOUSE E3 ubiquitin-protein ligase MARCH... | 66 | 0.00002 | 48.5 | 36 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB. | 11 | Q9NX47 | 278 | MARH5_HUMAN E3 ubiquitin-protein ligase MARCH... | 66 | 0.00002 | 48.5 | 36 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; IMP:UniProtKB.::GO:0090141; P:positive regulation of mitochondrial fission; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070585; P:protein localization in mitochondrion; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 12 | Q0X0A5 | 278 | MARH5_CHLAE E3 ubiquitin-protein ligase MARCH... | 66 | 0.00002 | 48.5 | 36 | 50 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB. | 13 | Q3ZC24 | 278 | MARH5_BOVIN E3 ubiquitin-protein ligase MARCH... | 66 | 0.00002 | 48.5 | 36 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB. | 14 | Q6NYK8 | 289 | MARH5_DANRE E3 ubiquitin-protein ligase MARCH... | 65 | 0.00002 | 48.5 | 32 | 43 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB. | 15 | P40318 | 1319 | DOA10_YEAST ERAD-associated E3 ubiquitin-prot... | 76 | 0.00002 | 49.3 | 37 | 42 | GO:0000837; C:Doa10p ubiquitin ligase complex; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005637; C:nuclear inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:SGD. | 16 | Q3TZ87 | 348 | MARH9_MOUSE E3 ubiquitin-protein ligase MARCH... | 128 | 0.00006 | 47.4 | 29 | 43 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 17 | Q86YJ5 | 346 | MARH9_HUMAN E3 ubiquitin-protein ligase MARCH... | 128 | 0.00006 | 47.4 | 29 | 43 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 18 | Q8TCQ1 | 289 | MARH1_HUMAN E3 ubiquitin-protein ligase MARCH... | 66 | 0.0005 | 44.7 | 36 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 19 | Q6NZQ8 | 289 | MARH1_MOUSE E3 ubiquitin-protein ligase MARCH... | 66 | 0.0005 | 44.3 | 36 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IMP:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 20 | Q5XI50 | 692 | MARH7_RAT E3 ubiquitin-protein ligase MARCH7 ... | 38 | 0.0008 | 44.3 | 45 | 61 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q9WV66 | 693 | MARH7_MOUSE E3 ubiquitin-protein ligase MARCH... | 38 | 0.0008 | 44.3 | 45 | 61 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 22 | Q1LVZ2 | 249 | MARH2_DANRE E3 ubiquitin-protein ligase MARCH... | 62 | 0.001 | 43.1 | 35 | 50 | GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 23 | Q5R9W2 | 707 | MARH7_PONAB E3 ubiquitin-protein ligase MARCH... | 38 | 0.001 | 43.9 | 45 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 24 | Q9H992 | 704 | MARH7_HUMAN E3 ubiquitin-protein ligase MARCH... | 38 | 0.001 | 43.5 | 45 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 25 | Q9DBD2 | 286 | MARH8_MOUSE E3 ubiquitin-protein ligase MARCH... | 64 | 0.001 | 43.1 | 39 | 48 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042289; F:MHC class II protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IDA:BHF-UCL. | 26 | Q5T0T0 | 291 | MARH8_HUMAN E3 ubiquitin-protein ligase MARCH... | 64 | 0.002 | 42.4 | 39 | 48 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 27 | Q0VD59 | 289 | MARH8_BOVIN E3 ubiquitin-protein ligase MARCH... | 64 | 0.002 | 42.4 | 39 | 48 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 28 | Q5R9W1 | 910 | MARH6_PONAB E3 ubiquitin-protein ligase MARCH... | 69 | 0.005 | 42 | 39 | 49 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 29 | Q6ZQ89 | 909 | MARH6_MOUSE E3 ubiquitin-protein ligase MARCH... | 69 | 0.005 | 42 | 39 | 49 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 30 | O60337 | 910 | MARH6_HUMAN E3 ubiquitin-protein ligase MARCH... | 69 | 0.005 | 42 | 39 | 49 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB. | 31 | Q28IK8 | 264 | MARH8_XENTR E3 ubiquitin-protein ligase MARCH... | 64 | 0.005 | 41.2 | 38 | 48 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
