| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | A6LPX4 | 419 | LEUC_CLOB8 3-isopropylmalate dehydratase larg... | 338 | 7e-38 | 150 | 32 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 62 | Q63270 | 889 | ACOC_RAT Cytoplasmic aconitate hydratase OS=R... | 824 | 8e-38 | 155 | 25 | 40 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005792; C:microsome; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048027; F:mRNA 5'-UTR binding; IDA:RGD. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IDA:RGD.::GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0006417; P:regulation of translation; TAS:RGD.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 63 | B9L6Y8 | 425 | LEUC_NAUPA 3-isopropylmalate dehydratase larg... | 468 | 8e-38 | 150 | 28 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 64 | P48200 | 963 | IREB2_HUMAN Iron-responsive element-binding p... | 781 | 9e-38 | 155 | 26 | 40 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006826; P:iron ion transport; TAS:UniProtKB. | 65 | O27668 | 428 | LEUC2_METTH 3-isopropylmalate dehydratase lar... | 353 | 1e-37 | 150 | 31 | 48 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 66 | Q6L0K5 | 413 | LEUC_PICTO 3-isopropylmalate dehydratase larg... | 373 | 1e-37 | 150 | 29 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 67 | Q2U9G3 | 775 | LYS4_ASPOR Homoaconitase, mitochondrial OS=As... | 533 | 2e-37 | 154 | 30 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 68 | Q5A644 | 684 | LYS4_CANAL Homoaconitase, mitochondrial OS=Ca... | 681 | 2e-37 | 153 | 27 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 69 | B4U7U5 | 424 | LEUC_HYDS0 3-isopropylmalate dehydratase larg... | 366 | 2e-37 | 149 | 30 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 70 | O67078 | 432 | LEUC_AQUAE 3-isopropylmalate dehydratase larg... | 368 | 4e-37 | 149 | 30 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 71 | Q6C791 | 687 | LYS4_YARLI Homoaconitase, mitochondrial OS=li... | 460 | 5e-37 | 152 | 30 | 46 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 72 | Q58409 | 420 | HACA_METJA Homoaconitase large subunit OS=JCM... | 352 | 6e-37 | 148 | 30 | 47 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:InterPro. | 73 | Q8U2A1 | 424 | LEUC1_PYRFU 3-isopropylmalate dehydratase lar... | 455 | 9e-37 | 147 | 28 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 74 | Q30NZ0 | 419 | LEUC_SULDN 3-isopropylmalate dehydratase larg... | 456 | 2e-36 | 147 | 29 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 75 | Q58FL6 | 769 | LYS4_ASPNC Homoaconitase, mitochondrial OS=As... | 519 | 2e-36 | 150 | 29 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 76 | Q0QLE2 | 420 | DMDA_EUBBA 2,3-dimethylmalate dehydratase lar... | 368 | 2e-36 | 146 | 31 | 46 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0047868; F:dimethylmaleate hydratase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro. | 77 | B2TIQ9 | 419 | LEUC_CLOBB 3-isopropylmalate dehydratase larg... | 336 | 2e-36 | 146 | 31 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 78 | Q811J3 | 963 | IREB2_MOUSE Iron-responsive element-binding p... | 784 | 3e-36 | 150 | 25 | 40 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0030350; F:iron-responsive element binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030371; F:translation repressor activity; TAS:MGI. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IDA:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0050892; P:intestinal absorption; IGI:MGI.::GO:0030316; P:osteoclast differentiation; IEP:DFLAT.::GO:0009791; P:post-embryonic development; IGI:MGI.::GO:0006782; P:protoporphyrinogen IX biosynthetic process; IMP:MGI. | 79 | Q24XT4 | 421 | LEUC_DESHY 3-isopropylmalate dehydratase larg... | 386 | 3e-36 | 146 | 30 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 80 | A4XJ48 | 429 | LEUC_CALS8 3-isopropylmalate dehydratase larg... | 334 | 3e-36 | 146 | 32 | 48 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 81 | B8CX22 | 420 | LEUC_HALOH 3-isopropylmalate dehydratase larg... | 439 | 4e-36 | 145 | 30 | 44 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 82 | Q62751 | 963 | IREB2_RAT Iron-responsive element-binding pro... | 783 | 7e-36 | 149 | 25 | 39 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.::GO:0030350; F:iron-responsive element binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 83 | Q6CT61 | 693 | LYS4_KLULA Homoaconitase, mitochondrial OS=12... | 676 | 8e-36 | 148 | 26 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 84 | B9MLV4 | 429 | LEUC_ANATD 3-isopropylmalate dehydratase larg... | 334 | 8e-36 | 145 | 32 | 48 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 85 | Q8TVF2 | 418 | LEUC1_METKA 3-isopropylmalate dehydratase lar... | 366 | 3e-35 | 143 | 29 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 86 | B2UYH6 | 419 | LEUC_CLOBA 3-isopropylmalate dehydratase larg... | 430 | 3e-35 | 143 | 28 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 87 | Q8TW29 | 402 | LEUC2_METKA 3-isopropylmalate dehydratase lar... | 455 | 3e-35 | 142 | 29 | 45 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 88 | A7IA28 | 416 | LEUC_METB6 3-isopropylmalate dehydratase larg... | 357 | 4e-35 | 142 | 30 | 44 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 89 | Q5ZLQ4 | 965 | IREB2_CHICK Iron-responsive element-binding p... | 767 | 1e-34 | 146 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008152; P:metabolic process; IEA:InterPro. | 90 | Q30WD3 | 418 | LEUC_DESDG 3-isopropylmalate dehydratase larg... | 455 | 1e-34 | 141 | 30 | 44 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 91 | A3DHI4 | 419 | LEUC_CLOTH 3-isopropylmalate dehydratase larg... | 342 | 2e-34 | 140 | 31 | 46 | | | | | | | | | | | GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. |
