| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q2YDN8 | 451 | VRK3_BOVIN Inactive serine/threonine-protein ... | 227 | 0.000000000000002 | 80.1 | 27 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | | 92 | Q19848 | 610 | VRK1_CAEEL Serine/threonine-protein kinase VR... | 364 | 0.000000000000005 | 79.3 | 23 | 42 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:WormBase.::GO:0007276; P:gamete generation; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IMP:WormBase. | 93 | Q8IV63 | 474 | VRK3_HUMAN Inactive serine/threonine-protein ... | 249 | 0.00000000000001 | 77.8 | 29 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | | 94 | O59790 | 355 | ARK1_SCHPO Serine/threonine-protein kinase ar... | 240 | 0.00000000000002 | 76.3 | 27 | 43 | GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase. | 95 | Q8K3G5 | 453 | VRK3_MOUSE Inactive serine/threonine-protein ... | 225 | 0.0000000000002 | 73.9 | 27 | 47 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:MGI. | | | | | | | | | | GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IPI:MGI.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IPI:MGI. | 96 | Q9J509 | 292 | V226_FOWPN Probable serine/threonine-protein ... | 300 | 0.0000000000003 | 72.8 | 25 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 97 | Q9XA16 | 673 | PKNX_STRCO Probable serine/threonine-protein ... | 221 | 0.0000000000003 | 73.9 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 98 | A8WYE4 | 1088 | PAR1_CAEBR Serine/threonine-protein kinase pa... | 292 | 0.0000000000007 | 73.2 | 27 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 99 | A8WU31 | 559 | VRK1_CAEBR Serine/threonine-protein kinase VR... | 258 | 0.0000000000007 | 72.8 | 26 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 100 | Q9TW45 | 1192 | PAR1_CAEEL Serine/threonine-protein kinase pa... | 292 | 0.0000000000008 | 73.2 | 27 | 44 | GO:0005938; C:cell cortex; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0009949; P:polarity specification of anterior/posterior axis; TAS:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 101 | A1A5Q6 | 654 | SMK_RAT Sperm motility kinase OS=Rattus norve... | 226 | 0.0000000000008 | 72.8 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 102 | P33973 | 693 | PKN1_MYXXA Serine/threonine-protein kinase Pk... | 226 | 0.000000000001 | 72.4 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035438; F:cyclic-di-GMP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 103 | P27466 | 446 | KCC1_YEAST Calcium/calmodulin-dependent prote... | 165 | 0.000000000002 | 71.6 | 29 | 53 | GO:0005737; C:cytoplasm; IPI:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0007165; P:signal transduction; IMP:SGD. | 104 | O34507 | 648 | PRKC_BACSU Serine/threonine-protein kinase Pr... | 223 | 0.000000000002 | 71.6 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0071224; P:cellular response to peptidoglycan; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0009847; P:spore germination; IMP:UniProtKB. | 105 | O22042 | 651 | M3K3_ARATH Mitogen-activated protein kinase k... | 219 | 0.000000000002 | 71.2 | 27 | 47 | GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 106 | P65726 | 431 | PKNA_MYCTU Probable serine/threonine-protein ... | 238 | 0.000000000002 | 70.9 | 27 | 45 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0051055; P:negative regulation of lipid biosynthetic process; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IDA:MTBBASE. | 107 | P65727 | 431 | PKNA_MYCBO Probable serine/threonine-protein ... | 238 | 0.000000000002 | 70.9 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 108 | Q17850 | 572 | PAK1_CAEEL Serine/threonine-protein kinase pa... | 210 | 0.000000000003 | 70.9 | 29 | 47 | GO:0030424; C:axon; IDA:WormBase.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; IDA:WormBase.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IGI:WormBase.::GO:0035262; P:gonad morphogenesis; IMP:WormBase.::GO:0031581; P:hemidesmosome assembly; IGI:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase. | 109 | O22040 | 666 | ANP1_ARATH Mitogen-activated protein kinase k... | 228 | 0.000000000003 | 70.9 | 28 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR. | 110 | O61661 | 512 | CHK1_DROME Serine/threonine-protein kinase gr... | 217 | 0.000000000003 | 70.5 | 28 | 43 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; IMP:UniProtKB.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase. | 111 | Q61083 | 619 | M3K2_MOUSE Mitogen-activated protein kinase k... | 245 | 0.000000000008 | 69.7 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 112 | Q9FZ36 | 651 | M3K2_ARATH Mitogen-activated protein kinase k... | 221 | 0.00000000001 | 69.3 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0000910; P:cytokinesis; IGI:TAIR. | 113 | O14299 | 1401 | WIS4_SCHPO MAP kinase kinase kinase wis4 OS=S... | 225 | 0.00000000001 | 69.3 | 28 | 48 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; NAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; NAS:PomBase. | 114 | Q02595 | 510 | KPK2_PLAFK Probable serine/threonine-protein ... | 210 | 0.00000000001 | 68.9 | 26 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 115 | Q9Y2U5 | 619 | M3K2_HUMAN Mitogen-activated protein kinase k... | 245 | 0.00000000001 | 68.9 | 27 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 116 | O14965 | 403 | AURKA_HUMAN Aurora kinase A OS=Homo sapiens (... | 243 | 0.00000000002 | 68.2 | 28 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB. | 117 | A5GFW1 | 402 | AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)... | 236 | 0.00000000002 | 68.2 | 28 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 118 | P59241 | 397 | AURKA_RAT Aurora kinase A OS=Rattus norvegicu... | 260 | 0.00000000002 | 67.8 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD. | 119 | Q7XJR9 | 571 | CDPKG_ARATH Calcium-dependent protein kinase ... | 215 | 0.00000000002 | 68.2 | 26 | 47 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 120 | Q8TDC3 | 778 | BRSK1_HUMAN Serine/threonine-protein kinase B... | 217 | 0.00000000003 | 68.2 | 29 | 47 | GO:0030054; C:cell junction; IDA:HPA.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IC:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB. | 121 | Q55FT4 | 2247 | TSUA_DICDI Probable serine/threonine-protein ... | 211 | 0.00000000003 | 68.6 | 27 | 45 | GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. |
