| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P58069 | 848 | RASA2_MOUSE Ras GTPase-activating protein 2 O... | 102 | 0.39 | 37.7 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 32 | Q63713 | 847 | RASA2_RAT Ras GTPase-activating protein 2 OS=... | 102 | 0.85 | 36.6 | 25 | 45 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 33 | Q15283 | 849 | RASA2_HUMAN Ras GTPase-activating protein 2 O... | 102 | 0.93 | 36.6 | 25 | 45 | GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 34 | Q22720 | 629 | GAP1_CAEEL Ras GTPase-activating protein gap-... | 153 | 0.00000002 | 61.2 | 26 | 50 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; NAS:UniProtKB. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IEP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 35 | Q54K32 | 822 | RGAA_DICDI Ras GTPase-activating-like protein... | 181 | 0.0006 | 47 | 21 | 43 | GO:0005938; C:cell cortex; TAS:dictyBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; ISS:dictyBase.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase.::GO:0005099; F:Ras GTPase activator activity; IDA:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031149; P:sorocarp stalk cell differentiation; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 36 | P33277 | 766 | GAP1_SCHPO GTPase-activating protein OS=Schiz... | 122 | 0.004 | 44.3 | 27 | 45 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IGI:PomBase. | | | | | | | | | | GO:0007265; P:Ras protein signal transduction; IC:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase. | 37 | Q9C5Y0 | 868 | PLDD1_ARATH Phospholipase D delta OS=Arabidop... | 100 | 0.005 | 43.9 | 31 | 42 | GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0004630; F:phospholipase D activity; IDA:TAIR. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046473; P:phosphatidic acid metabolic process; IMP:TAIR.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.::GO:0012501; P:programmed cell death; IMP:TAIR.::GO:0009409; P:response to cold; IMP:TAIR. | 38 | P18963 | 3092 | IRA1_YEAST Inhibitory regulator protein IRA1 ... | 266 | 0.009 | 43.5 | 23 | 41 | GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IMP:SGD. | | | | | | | | | | GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:SGD.::GO:0045761; P:regulation of adenylate cyclase activity; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 39 | Q6DN12 | 878 | MCTP2_HUMAN Multiple C2 and transmembrane dom... | 100 | 0.019 | 42 | 30 | 45 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; IDA:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 40 | Q5RJH2 | 878 | MCTP2_MOUSE Multiple C2 and transmembrane dom... | 100 | 0.019 | 42 | 30 | 45 | GO:0016021; C:integral to membrane; ISS:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:HGNC. | | | | | | | | | | | 41 | Q9D620 | 645 | RFIP1_MOUSE Rab11 family-interacting protein ... | 173 | 0.037 | 41.2 | 23 | 39 | GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 42 | Q3B7T9 | 648 | RFIP1_RAT Rab11 family-interacting protein 1 ... | 174 | 0.043 | 40.8 | 24 | 39 | GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 43 | Q6DN14 | 999 | MCTP1_HUMAN Multiple C2 and transmembrane dom... | 72 | 0.055 | 40.8 | 33 | 50 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 44 | Q28BX9 | 1014 | K0528_XENTR Uncharacterized protein KIAA0528 ... | 91 | 0.06 | 40.4 | 32 | 49 | | | | | | | | | | | | | | | | | | | | | | 45 | Q7TPS5 | 1016 | K0528_MOUSE Uncharacterized protein KIAA0528 ... | 91 | 0.1 | 39.7 | 32 | 49 | GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:MGI. | | | | | | | | | | GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IMP:MGI.::GO:0072659; P:protein localization in plasma membrane; IMP:MGI.::GO:0006906; P:vesicle fusion; IMP:MGI. | 46 | Q5RDC8 | 1000 | K0528_PONAB Uncharacterized protein KIAA0528 ... | 91 | 0.1 | 39.7 | 32 | 49 | | | | | | | | | | | | | | | | | | | | | | 47 | Q86YS7 | 1000 | K0528_HUMAN Uncharacterized protein KIAA0528 ... | 91 | 0.11 | 39.7 | 32 | 49 | | | | | | | | | | | | | | | | | | | | | | 48 | P19158 | 3079 | IRA2_YEAST Inhibitory regulator protein IRA2 ... | 182 | 0.12 | 39.7 | 20 | 44 | GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 49 | Q55AR6 | 920 | NFAA_DICDI Neurofibromin-A OS=Dictyostelium d... | 99 | 0.25 | 38.5 | 29 | 41 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; ISS:dictyBase. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0030833; P:regulation of actin filament polymerization; IMP:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 50 | Q7ZWU7 | 876 | EST2B_XENLA Extended synaptotagmin-2-B OS=Xen... | 99 | 0.32 | 38.1 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 51 | Q5FWL4 | 872 | EST2A_XENLA Extended synaptotagmin-2-A OS=Xen... | 99 | 0.34 | 38.1 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 52 | Q9VVI3 | 1007 | NEDD4_DROME E3 ubiquitin-protein ligase Nedd-... | 78 | 0.43 | 37.7 | 32 | 42 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB. | 53 | Q6WKZ4 | 1283 | RFIP1_HUMAN Rab11 family-interacting protein ... | 167 | 0.57 | 37.4 | 23 | 38 | GO:0005813; C:centrosome; IDA:HPA.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 54 | Q8CFI0 | 1004 | NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4... | 130 | 0.67 | 37 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 55 | Q9ZVT9 | 1020 | C2GR1_ARATH C2 and GRAM domain-containing pro... | 130 | 0.73 | 37 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 56 | Q54E35 | 570 | GACEE_DICDI Rho GTPase-activating protein gac... | 151 | 0.78 | 36.6 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 57 | Q3TZZ7 | 845 | ESYT2_MOUSE Extended synaptotagmin-2 OS=Mus m... | 101 | 0.83 | 37 | 27 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 58 | Q9PU36 | 5120 | PCLO_CHICK Protein piccolo OS=Gallus gallus (... | 140 | 1.2 | 36.6 | 26 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB. | 59 | Q12466 | 1186 | TCB1_YEAST Tricalbin-1 OS=Saccharomyces cerev... | 169 | 1.4 | 36.2 | 26 | 44 | GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | Q96PU5 | 975 | NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4... | 108 | 1.5 | 35.8 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB. | 61 | A0FGR8 | 921 | ESYT2_HUMAN Extended synaptotagmin-2 OS=Homo ... | 81 | 1.8 | 35.8 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | |
