rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P52643 | 329 | LDHD_ECOLI D-lactate dehydrogenase OS=Escheri... | 306 | 2e-29 | 121 | 30 | 47 | GO:0005625; C:soluble fraction; IDA:EcoCyc. | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IDA:EcoCyc.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0019664; P:glucose catabolic process to mixed acids; IDA:EcoCyc.::GO:0009408; P:response to heat; IEP:EcoliWiki. | 62 | Q9SXP2 | 376 | FDH1_ORYSJ Formate dehydrogenase 1, mitochond... | 247 | 3e-29 | 121 | 33 | 51 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 63 | Q5HLU4 | 317 | Y1888_STAEQ Putative 2-hydroxyacid dehydrogen... | 308 | 3e-29 | 120 | 31 | 52 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 64 | Q88VJ2 | 332 | LDHD_LACPL D-lactate dehydrogenase OS=Lactoba... | 259 | 3e-29 | 120 | 30 | 51 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 65 | Q8CNB8 | 317 | Y1879_STAES Putative 2-hydroxyacid dehydrogen... | 308 | 4e-29 | 120 | 31 | 52 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 66 | P17584 | 333 | DHD2_LACPA D-2-hydroxyisocaproate dehydrogena... | 317 | 7e-29 | 119 | 29 | 48 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 67 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 334 | 7e-29 | 120 | 31 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 68 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 299 | 8e-29 | 120 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 69 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 299 | 8e-29 | 120 | 31 | 49 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 70 | O46036 | 476 | CTBP_DROME C-terminal-binding protein OS=Dros... | 299 | 8e-29 | 120 | 31 | 48 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IDA:FlyBase.::GO:0003714; F:transcription corepressor activity; IDA:FlyBase. | | | | | | | | | | GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:FlyBase. | 71 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 332 | 1e-28 | 119 | 30 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 72 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 302 | 2e-28 | 119 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 73 | A1JT62 | 326 | GHRB_YERE8 Glyoxylate/hydroxypyruvate reducta... | 259 | 2e-28 | 118 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 74 | Q9EQH5 | 445 | CTBP2_RAT C-terminal-binding protein 2 OS=Rat... | 332 | 2e-28 | 119 | 30 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 75 | P56546 | 445 | CTBP2_MOUSE C-terminal-binding protein 2 OS=M... | 332 | 2e-28 | 119 | 30 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 76 | P30901 | 337 | LDHD_LACHE D-lactate dehydrogenase OS=Lactoba... | 234 | 3e-28 | 117 | 30 | 50 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 77 | Q9P7Q1 | 332 | DDH2_SCHPO 2-hydroxyacid dehydrogenase homolo... | 244 | 3e-28 | 117 | 31 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 78 | P36234 | 322 | DHGY_HYPME Glycerate dehydrogenase OS=Hyphomi... | 309 | 3e-28 | 117 | 30 | 45 | | | | | | | | | | | GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 79 | A4W577 | 324 | GHRB_ENT38 Glyoxylate/hydroxypyruvate reducta... | 285 | 4e-28 | 117 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 80 | Q9YHU0 | 440 | CTBP1_XENLA C-terminal-binding protein 1 OS=X... | 299 | 4e-28 | 118 | 30 | 48 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 81 | Q9UYR1 | 335 | GYAR_PYRAB Glyoxylate reductase OS=Pyrococcus... | 321 | 4e-28 | 117 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:HAMAP.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 82 | Q05709 | 322 | VANH_ENTFC D-specific alpha-keto acid dehydro... | 285 | 7e-28 | 116 | 32 | 48 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 83 | P26298 | 332 | LDHD_LACPE D-lactate dehydrogenase OS=Lactoba... | 259 | 9e-28 | 116 | 30 | 50 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 84 | Q663W4 | 326 | GHRB_YERPS Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 85 | A4TGN1 | 326 | GHRB_YERPP Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 86 | A9R4G6 | 326 | GHRB_YERPG Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 87 | Q0W9V5 | 326 | GHRB_YERPE Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 88 | B2K7F1 | 326 | GHRB_YERPB Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 89 | Q1C3K4 | 326 | GHRB_YERPA Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 90 | A7FPA2 | 326 | GHRB_YERP3 Glyoxylate/hydroxypyruvate reducta... | 259 | 1e-27 | 115 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 91 | A6TFG7 | 323 | GHRB_KLEP7 Glyoxylate/hydroxypyruvate reducta... | 281 | 1e-27 | 115 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | |