rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | B4N9D3 | 356 | WRNXO_DROWI Werner Syndrome-like exonuclease ... | 136 | 0.0003 | 47 | 29 | 47 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0045950; P:negative regulation of mitotic recombination; ISS:UniProtKB. | 2 | B3LWP6 | 355 | WRNXO_DROAN Werner Syndrome-like exonuclease ... | 183 | 0.002 | 44.7 | 24 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0045950; P:negative regulation of mitotic recombination; ISS:UniProtKB. | 3 | O09053 | 1401 | WRN_MOUSE Werner syndrome ATP-dependent helic... | 174 | 0.005 | 43.5 | 28 | 45 | GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0010259; P:multicellular organismal aging; IGI:MGI.::GO:0040009; P:regulation of growth rate; IMP:MGI.::GO:0001302; P:replicative cell aging; IMP:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI. | 4 | Q299L3 | 356 | WRNXO_DROPS Werner Syndrome-like exonuclease ... | 136 | 0.046 | 40 | 26 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0045950; P:negative regulation of mitotic recombination; ISS:UniProtKB. | 5 | Q14191 | 1432 | WRN_HUMAN Werner syndrome ATP-dependent helic... | 134 | 0.047 | 40.4 | 27 | 47 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.::GO:0010259; P:multicellular organismal aging; IMP:UniProtKB.::GO:0032066; P:nucleolus to nucleoplasm transport; IDA:MGI.::GO:0051345; P:positive regulation of hydrolase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IGI:MGI.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IDA:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:UniProtKB. | 6 | B4G5C9 | 355 | WRNXO_DROPE Werner Syndrome-like exonuclease ... | 136 | 0.049 | 40 | 26 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0045950; P:negative regulation of mitotic recombination; ISS:UniProtKB. | 7 | Q9WV74 | 336 | ASB1_MOUSE Ankyrin repeat and SOCS box protei... | 132 | 0.56 | 36.6 | 28 | 41 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030539; P:male genitalia development; IMP:MGI. | 8 | Q9XAZ1 | 416 | GLYA_NEIMF Serine hydroxymethyltransferase OS... | 122 | 4.4 | 33.9 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 9 | Q9XAY7 | 416 | GLYA_NEIMA Serine hydroxymethyltransferase OS... | 122 | 4.8 | 33.9 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 10 | P56990 | 416 | GLYA_NEIMB Serine hydroxymethyltransferase OS... | 122 | 5.1 | 33.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 11 | A9LYX4 | 416 | GLYA_NEIM0 Serine hydroxymethyltransferase OS... | 122 | 5.2 | 33.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 12 | Q5F8C0 | 416 | GLYA_NEIG1 Serine hydroxymethyltransferase OS... | 122 | 5.3 | 33.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 13 | Q9XB01 | 416 | GLYA_NEIGO Serine hydroxymethyltransferase OS... | 122 | 5.4 | 33.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 14 | B4RLC9 | 416 | GLYA_NEIG2 Serine hydroxymethyltransferase OS... | 122 | 5.7 | 33.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006544; P:glycine metabolic process; IEA:InterPro.::GO:0006563; P:L-serine metabolic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 15 | Q65T71 | 395 | SYY_MANSM Tyrosine--tRNA ligase OS=Mannheimia... | 90 | 7.5 | 33.1 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004831; F:tyrosine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006437; P:tyrosyl-tRNA aminoacylation; IEA:InterPro. | 16 | Q2HNT2 | 1078 | TSH1A_XENLA Teashirt homolog 1-A OS=Xenopus l... | 36 | 9.2 | 33.1 | 36 | 69 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |