| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q3KQ35 | 380 | S17AA_XENLA Transcription factor Sox-17-alpha... | 78 | 0.00000004 | 52.8 | 37 | 60 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0042074; P:cell migration involved in gastrulation; IMP:UniProtKB.::GO:0007492; P:endoderm development; IMP:UniProtKB.::GO:0007440; P:foregut morphogenesis; IMP:UniProtKB.::GO:0007442; P:hindgut morphogenesis; IMP:UniProtKB.::GO:0007494; P:midgut development; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 32 | P48431 | 317 | SOX2_HUMAN Transcription factor SOX-2 OS=Homo... | 80 | 0.00000004 | 52.4 | 39 | 61 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; TAS:BHF-UCL. | | | | | | | | | | GO:0035198; F:miRNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006325; P:chromatin organization; NAS:UniProtKB.::GO:0001714; P:endodermal cell fate specification; IDA:MGI.::GO:0021781; P:glial cell fate commitment; NAS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0070848; P:response to growth factor stimulus; IDA:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | P54231 | 320 | SOX2_SHEEP Transcription factor SOX-2 OS=Ovis... | 80 | 0.00000004 | 52.4 | 39 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL. | | | | | | | | | | GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | P43267 | 231 | SOX15_MOUSE Protein SOX-15 OS=Mus musculus (M... | 80 | 0.00000004 | 51.6 | 39 | 60 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0048627; P:myoblast development; IMP:MGI.::GO:0045843; P:negative regulation of striated muscle tissue development; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI. | 35 | Q6P0E1 | 315 | SOX2_DANRE Transcription factor Sox-2 OS=Dani... | 80 | 0.00000004 | 52.4 | 38 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IC:ZFIN. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048592; P:eye morphogenesis; IMP:ZFIN.::GO:0031101; P:fin regeneration; IMP:ZFIN.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 36 | P48432 | 319 | SOX2_MOUSE Transcription factor SOX-2 OS=Mus ... | 80 | 0.00000005 | 52.4 | 39 | 61 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0021984; P:adenohypophysis development; IMP:MGI.::GO:0001708; P:cell fate specification; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0050973; P:detection of mechanical stimulus involved in equilibrioception; IMP:MGI.::GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IMP:MGI.::GO:0048852; P:diencephalon morphogenesis; IMP:MGI.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IDA:MGI.::GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060235; P:lens induction in camera-type eye; IGI:MGI.::GO:0048286; P:lung alveolus development; IDA:MGI.::GO:0030539; P:male genitalia development; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0048663; P:neuron fate commitment; IMP:MGI.::GO:0097150; P:neuronal stem cell maintenance; IGI:UniProtKB.::GO:0030910; P:olfactory placode formation; IGI:MGI.::GO:0046148; P:pigment biosynthetic process; IMP:MGI.::GO:0030858; P:positive regulation of epithelial cell differentiation; IDA:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:MGI.::GO:0043586; P:tongue development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 37 | Q7SZS1 | 239 | SX21A_DANRE Transcription factor Sox-21-A OS=... | 80 | 0.00000005 | 51.6 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001071; F:nucleic acid binding transcription factor activity; IMP:ZFIN.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 38 | P40638 | 72 | AES2_ALLMI SRY-related protein AES2 OS=Alliga... | 80 | 0.00000005 | 49.7 | 40 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | P47792 | 297 | SX19A_DANRE Transcription factor Sox-19a OS=D... | 80 | 0.00000005 | 52 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 40 | Q8AWH3 | 383 | SX17A_XENTR Transcription factor Sox-17-alpha... | 80 | 0.00000005 | 52.4 | 39 | 61 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0007492; P:endoderm development; ISS:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 41 | Q06831 | 440 | SOX4_MOUSE Transcription factor SOX-4 OS=Mus ... | 81 | 0.00000006 | 52.4 | 38 | 59 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0035910; P:ascending aorta morphogenesis; IMP:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IMP:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0021782; P:glial cell development; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0002328; P:pro-B cell differentiation; IMP:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL. | 42 | P48433 | 312 | SOX3_CHICK Transcription factor SOX-3 OS=Gall... | 80 | 0.00000006 | 52 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0060324; P:face development; ISS:UniProtKB.::GO:0021854; P:hypothalamus development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0021983; P:pituitary gland development; ISS:UniProtKB.::GO:0007423; P:sensory organ development; ISS:UniProtKB. | 43 | Q9W7R5 | 280 | SOX21_CHICK Transcription factor SOX-21 OS=Ga... | 80 | 0.00000006 | 51.6 | 39 | 61 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | P40650 | 374 | SX11B_XENLA Transcription factor Sox-11-B OS=... | 80 | 0.00000006 | 52 | 39 | 59 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 45 | P53784 | 375 | SOX3_MOUSE Transcription factor SOX-3 OS=Mus ... | 80 | 0.00000007 | 52 | 40 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:UniProtKB. | | | | | | | | | | GO:0060324; P:face development; IMP:UniProtKB.::GO:0021854; P:hypothalamus development; IMP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0021983; P:pituitary gland development; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:UniProtKB.::GO:0060009; P:Sertoli cell development; IEP:UniProtKB.::GO:0007530; P:sex determination; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:MGI. | 46 | Q9DDD7 | 292 | SX19B_DANRE Transcription factor Sox-19b OS=D... | 80 | 0.00000007 | 51.6 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 47 | P41225 | 446 | SOX3_HUMAN Transcription factor SOX-3 OS=Homo... | 80 | 0.00000008 | 52 | 40 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0060324; P:face development; ISS:UniProtKB.::GO:0021854; P:hypothalamus development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0021983; P:pituitary gland development; ISS:UniProtKB.::GO:0007423; P:sensory organ development; ISS:UniProtKB.::GO:0007530; P:sex determination; IMP:UniProtKB. | 48 | Q66JF1 | 383 | SOX11_XENTR Transcription factor Sox-11 OS=Xe... | 80 | 0.00000008 | 52 | 39 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 49 | Q91731 | 382 | SX11A_XENLA Transcription factor Sox-11-A OS=... | 80 | 0.00000009 | 51.6 | 39 | 59 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | P55863 | 309 | SOX3A_XENLA Transcription factor Sox-3-A OS=X... | 80 | 0.0000001 | 51.2 | 38 | 60 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0001704; P:formation of primary germ layer; IMP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | P35716 | 441 | SOX11_HUMAN Transcription factor SOX-11 OS=Ho... | 80 | 0.0000001 | 52 | 39 | 59 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0061386; P:closure of optic fissure; ISS:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060022; P:hard palate development; ISS:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0060425; P:lung morphogenesis; ISS:UniProtKB.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; IMP:UniProtKB.::GO:0050672; P:negative regulation of lymphocyte proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; ISS:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; ISS:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:UniProtKB.::GO:0045778; P:positive regulation of ossification; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEP:UniProtKB.::GO:0072404; P:signal transduction involved in G1/S transition checkpoint; IEP:UniProtKB.::GO:0060023; P:soft palate development; ISS:UniProtKB.::GO:0061053; P:somite development; ISS:UniProtKB.::GO:0021510; P:spinal cord development; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; ISS:UniProtKB. | 52 | P0C1G9 | 395 | SOX11_RAT Transcription factor SOX-11 OS=Ratt... | 80 | 0.0000001 | 51.6 | 39 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; ISS:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0061386; P:closure of optic fissure; ISS:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060022; P:hard palate development; ISS:UniProtKB.::GO:0001822; P:kidney development; IEP:RGD.::GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0060425; P:lung morphogenesis; ISS:UniProtKB.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; ISS:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; ISS:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0045778; P:positive regulation of ossification; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.::GO:0060023; P:soft palate development; ISS:UniProtKB.::GO:0061053; P:somite development; ISS:UniProtKB.::GO:0021510; P:spinal cord development; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; ISS:UniProtKB. | 53 | Q7M6Y2 | 395 | SOX11_MOUSE Transcription factor SOX-11 OS=Mu... | 80 | 0.0000001 | 51.6 | 39 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0008135; F:translation factor activity, nucleic acid binding; ISS:UniProtKB. | | | | | | | | | | GO:0003211; P:cardiac ventricle formation; IMP:UniProtKB.::GO:0061386; P:closure of optic fissure; IMP:UniProtKB.::GO:0061303; P:cornea development in camera-type eye; IMP:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:UniProtKB.::GO:0048704; P:embryonic skeletal system morphogenesis; IMP:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; IMP:UniProtKB.::GO:0014009; P:glial cell proliferation; IMP:UniProtKB.::GO:0060022; P:hard palate development; IMP:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; IMP:UniProtKB.::GO:0060174; P:limb bud formation; IMP:UniProtKB.::GO:0060425; P:lung morphogenesis; IMP:UniProtKB.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0060253; P:negative regulation of glial cell proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0001841; P:neural tube formation; IMP:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; IMP:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; IMP:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; IMP:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0035332; P:positive regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0046887; P:positive regulation of hormone secretion; IMP:UniProtKB.::GO:2001111; P:positive regulation of lens epithelial cell proliferation; IMP:UniProtKB.::GO:0050769; P:positive regulation of neurogenesis; IDA:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IDA:UniProtKB.::GO:0045778; P:positive regulation of ossification; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.::GO:0060023; P:soft palate development; IMP:UniProtKB.::GO:0061053; P:somite development; IMP:UniProtKB.::GO:0021510; P:spinal cord development; IMP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; IMP:UniProtKB.::GO:0060412; P:ventricular septum morphogenesis; IMP:UniProtKB. | 54 | P36389 | 223 | SRY_HORSE Sex-determining region Y protein OS... | 80 | 0.0000001 | 50.1 | 39 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | Q90ZH9 | 377 | S17AB_XENLA Transcription factor Sox-17-alpha... | 80 | 0.0000001 | 51.2 | 38 | 61 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0042074; P:cell migration involved in gastrulation; IMP:UniProtKB.::GO:0007492; P:endoderm development; IMP:UniProtKB.::GO:0007442; P:hindgut morphogenesis; IMP:UniProtKB.::GO:0007494; P:midgut development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 56 | Q06945 | 474 | SOX4_HUMAN Transcription factor SOX-4 OS=Homo... | 80 | 0.0000002 | 51.2 | 39 | 59 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.::GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.::GO:0021782; P:glial cell development; ISS:UniProtKB.::GO:0014009; P:glial cell proliferation; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:BHF-UCL.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0001841; P:neural tube formation; ISS:UniProtKB.::GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.::GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:UniProtKB.::GO:0002328; P:pro-B cell differentiation; ISS:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.::GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL. | 57 | Q24533 | 382 | DICH_DROME SOX domain-containing protein dich... | 81 | 0.0000002 | 51.2 | 36 | 60 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IDA:FlyBase.::GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0007420; P:brain development; IMP:FlyBase.::GO:0009950; P:dorsal/ventral axis specification; IMP:FlyBase.::GO:0007442; P:hindgut morphogenesis; IMP:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0060810; P:intracellular mRNA localization involved in pattern specification process; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0035120; P:post-embryonic appendage morphogenesis; IMP:FlyBase. | 58 | Q6GLH8 | 373 | S17B2_XENTR Transcription factor Sox-17-beta.... | 80 | 0.0000002 | 51.2 | 38 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 59 | P48435 | 396 | SOX11_CHICK Transcription factor SOX-11 OS=Ga... | 80 | 0.0000002 | 50.8 | 39 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 60 | Q6F2F0 | 376 | S17B3_XENTR Transcription factor Sox-17-beta.... | 80 | 0.0000002 | 50.8 | 38 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 61 | P36395 | 208 | SRY_SMIMA Sex-determining region Y protein OS... | 80 | 0.0000002 | 49.7 | 36 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
