rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O74831 | 158 | FRDA_SCHPO Frataxin homolog, mitochondrial OS... | 109 | 1e-32 | 117 | 50 | 70 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0030234; F:enzyme regulator activity; ISS:PomBase.::GO:0004322; F:ferroxidase activity; IEA:EC.::GO:0005506; F:iron ion binding; ISS:PomBase. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; ISS:PomBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; ISS:PomBase.::GO:0072592; P:oxygen metabolic process; ISS:PomBase. | 2 | Q16595 | 210 | FRDA_HUMAN Frataxin, mitochondrial OS=Homo sa... | 108 | 2e-27 | 105 | 54 | 68 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005759; C:mitochondrial matrix; ISS:BHF-UCL. | | | | | | | | | | GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:BHF-UCL.::GO:0008199; F:ferric iron binding; IDA:BHF-UCL.::GO:0008198; F:ferrous iron binding; IDA:BHF-UCL.::GO:0004322; F:ferroxidase activity; IDA:UniProtKB.::GO:0034986; F:iron chaperone activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0006783; P:heme biosynthetic process; NAS:BHF-UCL.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; IDA:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0051349; P:positive regulation of lyase activity; IDA:UniProtKB.::GO:0048554; P:positive regulation of metalloenzyme activity; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IMP:BHF-UCL.::GO:0051347; P:positive regulation of transferase activity; IMP:BHF-UCL.::GO:0016540; P:protein autoprocessing; IDA:BHF-UCL.::GO:0010722; P:regulation of ferrochelatase activity; IDA:BHF-UCL.::GO:0010039; P:response to iron ion; IMP:BHF-UCL. | 3 | Q8HXX9 | 210 | FRDA_MACFA Frataxin, mitochondrial OS=Macaca ... | 108 | 3e-27 | 105 | 54 | 67 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 4 | O35943 | 207 | FRDA_MOUSE Frataxin, mitochondrial OS=Mus mus... | 108 | 7e-27 | 103 | 53 | 68 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0009060; P:aerobic respiration; IMP:MGI.::GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:MGI.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:MGI.::GO:0006119; P:oxidative phosphorylation; IMP:MGI.::GO:0019230; P:proprioception; IMP:MGI. | 5 | Q05B87 | 217 | FRDA_BOVIN Frataxin, mitochondrial OS=Bos tau... | 110 | 9e-27 | 103 | 52 | 66 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 6 | Q54C45 | 193 | FRDA_DICDI Frataxin, mitochondrial OS=Dictyos... | 99 | 4e-26 | 101 | 46 | 64 | GO:0005739; C:mitochondrion; ISS:dictyBase. | | | | | | | | | | GO:0030234; F:enzyme regulator activity; ISS:dictyBase.::GO:0008198; F:ferrous iron binding; ISS:dictyBase.::GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; ISS:dictyBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; ISS:dictyBase. | 7 | Q07540 | 174 | FRDA_YEAST Frataxin homolog, mitochondrial OS... | 106 | 6e-26 | 100 | 47 | 66 | GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; IDA:SGD. | | | | | | | | | | GO:0008198; F:ferrous iron binding; IDA:SGD.::GO:0004322; F:ferroxidase activity; IDA:SGD.::GO:0034986; F:iron chaperone activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0006749; P:glutathione metabolic process; IMP:SGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.::GO:0006121; P:mitochondrial electron transport, succinate to ubiquinone; IMP:UniProtKB.::GO:0010040; P:response to iron(II) ion; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IMP:UniProtKB. | 8 | Q9ZR07 | 187 | FRDA_ARATH Frataxin, mitochondrial OS=Arabido... | 85 | 6e-25 | 98.6 | 51 | 72 | GO:0005739; C:mitochondrion; ISS:TAIR. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0009060; P:aerobic respiration; IMP:TAIR.::GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0042542; P:response to hydrogen peroxide; IMP:TAIR. | 9 | Q9W385 | 190 | FRDA_DROME Frataxin homolog, mitochondrial OS... | 100 | 2e-23 | 94.4 | 46 | 66 | GO:0005739; C:mitochondrion; IMP:FlyBase. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC.::GO:0034986; F:iron chaperone activity; IDA:FlyBase. | | | | | | | | | | GO:0019896; P:axon transport of mitochondrion; IDA:FlyBase.::GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0051881; P:regulation of mitochondrial membrane potential; IDA:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase. | 10 | Q9TY03 | 136 | FRDA_CAEEL Frataxin, mitochondrial OS=Caenorh... | 113 | 4e-22 | 89.7 | 46 | 59 | GO:0005739; C:mitochondrion; IDA:WormBase. | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0042542; P:response to hydrogen peroxide; IMP:WormBase.::GO:0000303; P:response to superoxide; IMP:WormBase. | 11 | D3ZYW7 | 208 | FRDA_RAT Frataxin, mitochondrial OS=Rattus no... | 108 | 1e-21 | 90.5 | 46 | 62 | GO:0005739; C:mitochondrion; IDA:RGD. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004322; F:ferroxidase activity; IEA:EC. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; NAS:RGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 12 | Q8SWI3 | 118 | FRDA_ENCCU Frataxin, mitosomal OS=Encephalito... | 102 | 0.0000000000007 | 64.7 | 34 | 53 | GO:0032047; C:mitosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 13 | B5BIV3 | 106 | CYAY_SALPK Protein CyaY OS=Salmonella paratyp... | 107 | 0.000000000006 | 62 | 33 | 49 | | | | | | | | | | | | | | | | | | | | | | 14 | Q5PKM9 | 106 | CYAY_SALPA Protein CyaY OS=Salmonella paratyp... | 107 | 0.000000000006 | 62 | 33 | 49 | | | | | | | | | | | | | | | | | | | | | | 15 | A9MY64 | 106 | CYAY_SALPB Protein CyaY OS=Salmonella paratyp... | 107 | 0.00000000004 | 59.7 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 16 | Q3K4S1 | 110 | CYAY_PSEPF Protein CyaY OS=Pseudomonas fluore... | 94 | 0.00000000006 | 59.3 | 37 | 62 | | | | | | | | | | | | | | | | | | | | | | 17 | P56978 | 106 | CYAY_SALTY Protein CyaY OS=Salmonella typhimu... | 107 | 0.00000000008 | 58.9 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 18 | Q8Z3A4 | 106 | CYAY_SALTI Protein CyaY OS=Salmonella typhi. ... | 107 | 0.0000000001 | 58.5 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 19 | B5RFQ2 | 106 | CYAY_SALG2 Protein CyaY OS=Salmonella gallina... | 107 | 0.0000000001 | 58.5 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 20 | B5QVJ3 | 106 | CYAY_SALEP Protein CyaY OS=Salmonella enterit... | 107 | 0.0000000001 | 58.5 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 21 | B5FNU2 | 106 | CYAY_SALDC Protein CyaY OS=Salmonella dublin ... | 107 | 0.0000000001 | 58.5 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 22 | B4TNV5 | 106 | CYAY_SALSV Protein CyaY OS=Salmonella schwarz... | 107 | 0.0000000001 | 58.5 | 31 | 48 | | | | | | | | | | | | | | | | | | | | | | 23 | Q8FBN9 | 106 | CYAY_ECOL6 Protein CyaY OS=Escherichia coli O... | 107 | 0.0000000001 | 58.2 | 31 | 48 | | | | | | | | | | | | | | | | | | | | | | 24 | B8GQ85 | 107 | CYAY_THISH Protein CyaY OS=Thioalkalivibrio s... | 105 | 0.0000000001 | 58.2 | 31 | 50 | | | | | | | | | | | | | | | | | | | | | | 25 | B4SZ48 | 106 | CYAY_SALNS Protein CyaY OS=Salmonella newport... | 107 | 0.0000000002 | 57.8 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 26 | Q92IH7 | 103 | CYAY_RICCN Protein CyaY OS=Rickettsia conorii... | 101 | 0.0000000003 | 57.4 | 35 | 55 | | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:InterPro. | | | | | | | | | | | 27 | C3PN35 | 103 | CYAY_RICAE Protein CyaY OS=Rickettsia africae... | 101 | 0.0000000003 | 57.4 | 35 | 55 | | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:InterPro. | | | | | | | | | | | 28 | P56977 | 107 | CYAY_NEIMB Protein CyaY OS=Neisseria meningit... | 96 | 0.0000000003 | 57.4 | 27 | 54 | | | | | | | | | | | | | | | | | | | | | | 29 | B4TB34 | 106 | CYAY_SALHS Protein CyaY OS=Salmonella heidelb... | 107 | 0.0000000003 | 57.4 | 30 | 48 | | | | | | | | | | | | | | | | | | | | | | 30 | C4K1X9 | 103 | CYAY_RICPU Protein CyaY OS=Rickettsia peacock... | 101 | 0.0000000003 | 57.4 | 35 | 54 | | | | | | | | | | | GO:0004322; F:ferroxidase activity; IEA:InterPro. | | | | | | | | | | | 31 | A9MJ08 | 106 | CYAY_SALAR Protein CyaY OS=Salmonella arizona... | 107 | 0.0000000003 | 57 | 31 | 48 | | | | | | | | | | | | | | | | | | | | | |