rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P0CN14 | 644 | DOT1_CRYNJ Histone-lysine N-methyltransferase... | 454 | 2e-62 | 219 | 34 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
2 | P0CN15 | 644 | DOT1_CRYNB Histone-lysine N-methyltransferase... | 449 | 3e-62 | 218 | 34 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
3 | Q4P2W8 | 798 | DOT1_USTMA Histone-lysine N-methyltransferase... | 56 | 0.0000000004 | 65.5 | 54 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
4 | Q1DKD8 | 499 | DOT1_COCIM Histone-lysine N-methyltransferase... | 52 | 0.002 | 43.9 | 35 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
5 | Q2U696 | 335 | DOT1_ASPOR Histone-lysine N-methyltransferase... | 219 | 9e-50 | 177 | 38 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
6 | Q5BH89 | 501 | DOT1_EMENI Histone-lysine N-methyltransferase... | 41 | 0.28 | 37.4 | 32 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
7 | Q6C4Y5 | 492 | DOT1_YARLI Histone-lysine N-methyltransferase... | 220 | 1e-47 | 176 | 40 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
8 | Q2H9L1 | 510 | DOT1_CHAGB Histone-lysine N-methyltransferase... | 272 | 1e-46 | 173 | 36 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
9 | Q4WVH4 | 502 | DOT1_ASPFU Histone-lysine N-methyltransferase... | 49 | 0.018 | 40.8 | 37 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
10 | Q4IJP1 | 493 | DOT1_GIBZE Histone-lysine N-methyltransferase... | 278 | 2e-46 | 172 | 36 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
11 | Q7SB74 | 531 | DOT1_NEUCR Histone-lysine N-methyltransferase... | 379 | 2e-45 | 170 | 30 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
12 | Q04089 | 582 | DOT1_YEAST Histone-lysine N-methyltransferase... | 279 | 2e-37 | 147 | 31 | 54 | GO:0005634; C:nucleus; IDA:SGD. |
| | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:SGD.::GO:0031493; F:nucleosomal histone binding; IDA:SGD. |
| | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0070911; P:global genome nucleotide-excision repair; IMP:SGD.::GO:0000725; P:recombinational repair; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
13 | Q756E1 | 575 | DOT1_ASHGO Histone-lysine N-methyltransferase... | 278 | 5e-34 | 137 | 31 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
14 | Q6CWV1 | 572 | DOT1_KLULA Histone-lysine N-methyltransferase... | 228 | 3e-32 | 132 | 34 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
15 | Q8TEK3 | 1739 | DOT1L_HUMAN Histone-lysine N-methyltransferas... | 249 | 9e-32 | 133 | 34 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. |
| | | | | | | | | GO:0046425; P:regulation of JAK-STAT cascade; IDA:UniProtKB.::GO:2000677; P:regulation of transcription regulatory region DNA binding; IMP:UniProtKB. |
16 | Q6FNM5 | 652 | DOT1_CANGA Histone-lysine N-methyltransferase... | 224 | 1e-28 | 122 | 31 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
17 | Q8INR6 | 1848 | DOT1L_DROME Histone-lysine N-methyltransferas... | 233 | 1e-26 | 117 | 35 | 51 | GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. |
| | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IMP:UniProtKB. |
| | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:UniProtKB.::GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB. |
18 | Q5A309 | 1343 | DOT1_CANAL Histone-lysine N-methyltransferase... | 243 | 1e-18 | 92.8 | 28 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
19 | Q6BTC8 | 1172 | DOT1_DEBHA Histone-lysine N-methyltransferase... | 218 | 6e-18 | 90.1 | 29 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. |
| | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
20 | Q55AX2 | 1845 | DOT1L_DICDI Histone-lysine N-methyltransferas... | 205 | 0.000000002 | 63.5 | 28 | 45 | GO:0005634; C:nucleus; IDA:dictyBase. |
| | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:dictyBase. |
| | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
21 | F6HH45 | 510 | TRM52_VITVI tRNA (guanine(37)-N1)-methyltrans... | 94 | 0.046 | 39.7 | 31 | 47 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0052906; F:tRNA (guanine(37)-N(1))-methyltransferase activity; IEA:EC. |
| | | | | | | | | |
22 | Q8LDU5 | 466 | PP298_ARATH Pentatricopeptide repeat-containi... | 204 | 0.22 | 37.4 | 25 | 40 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. |
| | | | | | | | | |
| | | | | | | | | |
23 | Q4JBL7 | 192 | CBIT_SULAC Probable cobalt-precorrin-6Y C(15)... | 69 | 0.28 | 36.2 | 35 | 49 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
24 | B1YS64 | 369 | LPXD_BURA4 UDP-3-O-acylglucosamine N-acyltran... | 108 | 2.1 | 34.3 | 26 | 48 | |
| | | | | | | | | GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. |
| | | | | | | | | GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW. |
25 | Q5FAH7 | 295 | PRMA_NEIG1 Ribosomal protein L11 methyltransf... | 58 | 2.1 | 34.3 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | |
26 | C3N8G6 | 199 | CBIT_SULIY Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
27 | C3NJQ5 | 199 | CBIT_SULIN Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
28 | C3MTW8 | 199 | CBIT_SULIM Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
29 | C3MJI5 | 199 | CBIT_SULIL Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
30 | C4KJM8 | 199 | CBIT_SULIK Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |
31 | C3N0H8 | 199 | CBIT_SULIA Probable cobalt-precorrin-6Y C(15)... | 51 | 2.4 | 33.5 | 31 | 57 | |
| | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. |
| | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. |