Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
218607
Length:
239
Number of sequences:
10438
Description:
estExt_Genewise1.C_31200
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961P93025    915   PHOT2_ARATH Phototropin-2 OS=Arabidopsis thal...2330.00000000003     66.2     26     42GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IMP:TAIR.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009902; P:chloroplast relocation; TAS:TAIR.::GO:0010362; P:negative regulation of anion channel activity by blue light; IMP:TAIR.::GO:0009638; P:phototropism; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; TAS:TAIR.::GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR.
962Q05512    776   MARK2_MOUSE Serine/threonine-protein kinase M...1980.00000000003     66.2     27     48GO:0045180; C:basal cortex; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
963Q54WX4    384   AURK_DICDI Aurora kinase OS=Dictyostelium dis...2370.00000000003     65.5     24     43GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IDA:dictyBase.::GO:0051233; C:spindle midzone; IDA:dictyBase.::GO:0000922; C:spindle pole; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000278; P:mitotic cell cycle; ISS:dictyBase.
964Q90Z00    810   FGR1A_DANRE Fibroblast growth factor receptor...2580.00000000003     66.2     26     45GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:ZFIN.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:ZFIN.::GO:0008201; F:heparin binding; ISS:UniProtKB.
GO:0060249; P:anatomical structure homeostasis; IMP:ZFIN.::GO:0048738; P:cardiac muscle tissue development; IMP:ZFIN.::GO:0009953; P:dorsal/ventral pattern formation; IMP:ZFIN.::GO:0031101; P:fin regeneration; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0042664; P:negative regulation of endodermal cell fate specification; IGI:ZFIN.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.::GO:0048916; P:posterior lateral line development; IMP:ZFIN.::GO:0043589; P:skin morphogenesis; IMP:ZFIN.
965Q15569    626   TESK1_HUMAN Dual specificity testis-specific ...1620.00000000003     65.9     33     52GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.
966Q7ZUQ3    492   STK3_DANRE Serine/threonine-protein kinase 3 ...2460.00000000003     65.9     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
967Q5IS82    825   NTRK3_SAIBB NT-3 growth factor receptor OS=Sa...2300.00000000003     66.2     27     44GO:0005887; C:integral to plasma membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
968Q94CU5    943   NEK5_ORYSJ Serine/threonine-protein kinase Ne...1910.00000000003     66.2     24     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
969P32491    506   MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Sa...1470.00000000003     65.9     29     50GO:0005622; C:intracellular; TAS:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030242; P:peroxisome degradation; IGI:SGD.::GO:0007165; P:signal transduction; IMP:SGD.
970Q61527    1308   ERBB4_MOUSE Receptor tyrosine-protein kinase ...2480.00000000003     66.2     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0061026; P:cardiac muscle tissue regeneration; IMP:UniProtKB.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0021551; P:central nervous system morphogenesis; IMP:UniProtKB.::GO:0009880; P:embryonic pattern specification; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0007595; P:lactation; IMP:UniProtKB.::GO:0060749; P:mammary gland alveolus development; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0021889; P:olfactory bulb interneuron differentiation; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:2000366; P:positive regulation of STAT protein import into nucleus; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.
971Q5W736    457   CIPKI_ORYSJ CBL-interacting protein kinase 18...2430.00000000003     65.9     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
972Q9ZNQ8    633   PERK4_ARATH Proline-rich receptor-like protei...1410.00000000003     65.9     34     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0019722; P:calcium-mediated signaling; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0009845; P:seed germination; IMP:TAIR.
973P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...1810.00000000003     65.1     28     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
974Q9ZUI0    980   Y2241_ARATH Putative leucine-rich repeat rece...2130.00000000004     66.2     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
975Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...1890.00000000004     65.9     23     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
976Q9STF0    337   LRKS3_ARATH Receptor like protein kinase S.3 ...1970.00000000004     65.5     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
977P13863    303   CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallu...2130.00000000004     65.1     23     44GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
978Q8SSS9    1553   QKGA_DICDI Probable serine/threonine-protein ...2220.00000000004     66.2     27     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IMP:dictyBase.
979Q8MY86    854   FGFR1_DUGJA Fibroblast growth factor receptor...2410.00000000004     65.9     24     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC.
980Q7ZZC8    944   NEK9_XENLA Serine/threonine-protein kinase Ne...2120.00000000004     66.2     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
981Q9FJ54    439   CIPKK_ARATH CBL-interacting serine/threonine-...2470.00000000004     65.5     24     47GO:0005829; C:cytosol; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:TAIR.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
982P43063    317   CDK1_CANAL Cyclin-dependent kinase 1 OS=Candi...1800.00000000004     65.1     24     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:CGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:CGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IGI:CGD.
983Q00536    496   CDK16_HUMAN Cyclin-dependent kinase 16 OS=Hom...1710.00000000004     65.9     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
984Q552C6    635   ZAK2_DICDI Dual specificity protein kinase za...1750.00000002     57.4     25     42
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase.
GO:0045860; P:positive regulation of protein kinase activity; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0010468; P:regulation of gene expression; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
985Q21734    784   KS6A1_CAEEL Putative ribosomal protein S6 kin...2180.0000005     53.5     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
986Q5R4K3    802   KS6A5_PONAB Ribosomal protein S6 kinase alpha...1490.000002     51.6     26     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
987P52332    1153   JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mu...2100.000006     50.4     23     45GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
988P23458    1154   JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Ho...2130.000007     50.1     23     45GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
989Q9R117    1180   TYK2_MOUSE Non-receptor tyrosine-protein kina...2220.0001     46.2     23     42GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
990Q62689    1132   JAK2_RAT Tyrosine-protein kinase JAK2 OS=Ratt...2190.004     41.6     21     40GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016363; C:nuclear matrix; IDA:RGD.
GO:0033130; F:acetylcholine receptor binding; IPI:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035401; F:histone kinase activity (H3-Y41 specific); ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0051428; F:peptide hormone receptor binding; IPI:RGD.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0031702; F:type 1 angiotensin receptor binding; IPI:RGD.
GO:0042977; P:activation of JAK2 kinase activity; ISS:UniProtKB.::GO:0000186; P:activation of MAPKK activity; IMP:RGD.::GO:0031103; P:axon regeneration; IMP:RGD.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:RGD.::GO:0009755; P:hormone-mediated signaling pathway; IDA:RGD.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:RGD.::GO:0060333; P:interferon-gamma-mediated signaling pathway; IDA:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.::GO:0031959; P:mineralocorticoid receptor signaling pathway; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:RGD.::GO:0050867; P:positive regulation of cell activation; IMP:RGD.::GO:0045597; P:positive regulation of cell differentiation; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0043388; P:positive regulation of DNA binding; IMP:RGD.::GO:0050729; P:positive regulation of inflammatory response; IMP:RGD.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.::GO:0032731; P:positive regulation of interleukin-1 beta production; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IMP:RGD.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0033194; P:response to hydroperoxide; IMP:RGD.::GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IMP:RGD.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IMP:RGD.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IMP:RGD.
991O12990    1153   JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Da...1660.004     42     22     43GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
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