rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
961 | P93025 | 915 | PHOT2_ARATH Phototropin-2 OS=Arabidopsis thal... | 233 | 0.00000000003 | 66.2 | 26 | 42 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IMP:TAIR.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009902; P:chloroplast relocation; TAS:TAIR.::GO:0010362; P:negative regulation of anion channel activity by blue light; IMP:TAIR.::GO:0009638; P:phototropism; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; TAS:TAIR.::GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR. | 962 | Q05512 | 776 | MARK2_MOUSE Serine/threonine-protein kinase M... | 198 | 0.00000000003 | 66.2 | 27 | 48 | GO:0045180; C:basal cortex; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 963 | Q54WX4 | 384 | AURK_DICDI Aurora kinase OS=Dictyostelium dis... | 237 | 0.00000000003 | 65.5 | 24 | 43 | GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IDA:dictyBase.::GO:0051233; C:spindle midzone; IDA:dictyBase.::GO:0000922; C:spindle pole; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000278; P:mitotic cell cycle; ISS:dictyBase. | 964 | Q90Z00 | 810 | FGR1A_DANRE Fibroblast growth factor receptor... | 258 | 0.00000000003 | 66.2 | 26 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:ZFIN.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:ZFIN.::GO:0008201; F:heparin binding; ISS:UniProtKB. | | | | | | | | | | GO:0060249; P:anatomical structure homeostasis; IMP:ZFIN.::GO:0048738; P:cardiac muscle tissue development; IMP:ZFIN.::GO:0009953; P:dorsal/ventral pattern formation; IMP:ZFIN.::GO:0031101; P:fin regeneration; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0042664; P:negative regulation of endodermal cell fate specification; IGI:ZFIN.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.::GO:0048916; P:posterior lateral line development; IMP:ZFIN.::GO:0043589; P:skin morphogenesis; IMP:ZFIN. | 965 | Q15569 | 626 | TESK1_HUMAN Dual specificity testis-specific ... | 162 | 0.00000000003 | 65.9 | 33 | 52 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 966 | Q7ZUQ3 | 492 | STK3_DANRE Serine/threonine-protein kinase 3 ... | 246 | 0.00000000003 | 65.9 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 967 | Q5IS82 | 825 | NTRK3_SAIBB NT-3 growth factor receptor OS=Sa... | 230 | 0.00000000003 | 66.2 | 27 | 44 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 968 | Q94CU5 | 943 | NEK5_ORYSJ Serine/threonine-protein kinase Ne... | 191 | 0.00000000003 | 66.2 | 24 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 969 | P32491 | 506 | MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Sa... | 147 | 0.00000000003 | 65.9 | 29 | 50 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030242; P:peroxisome degradation; IGI:SGD.::GO:0007165; P:signal transduction; IMP:SGD. | 970 | Q61527 | 1308 | ERBB4_MOUSE Receptor tyrosine-protein kinase ... | 248 | 0.00000000003 | 66.2 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0061026; P:cardiac muscle tissue regeneration; IMP:UniProtKB.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0021551; P:central nervous system morphogenesis; IMP:UniProtKB.::GO:0009880; P:embryonic pattern specification; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0007595; P:lactation; IMP:UniProtKB.::GO:0060749; P:mammary gland alveolus development; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0021889; P:olfactory bulb interneuron differentiation; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:2000366; P:positive regulation of STAT protein import into nucleus; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB. | 971 | Q5W736 | 457 | CIPKI_ORYSJ CBL-interacting protein kinase 18... | 243 | 0.00000000003 | 65.9 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 972 | Q9ZNQ8 | 633 | PERK4_ARATH Proline-rich receptor-like protei... | 141 | 0.00000000003 | 65.9 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0019722; P:calcium-mediated signaling; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0009845; P:seed germination; IMP:TAIR. | 973 | P17157 | 305 | PHO85_YEAST Cyclin-dependent protein kinase P... | 181 | 0.00000000003 | 65.1 | 28 | 49 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD. | 974 | Q9ZUI0 | 980 | Y2241_ARATH Putative leucine-rich repeat rece... | 213 | 0.00000000004 | 66.2 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 975 | Q8IVW4 | 592 | CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS... | 189 | 0.00000000004 | 65.9 | 23 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 976 | Q9STF0 | 337 | LRKS3_ARATH Receptor like protein kinase S.3 ... | 197 | 0.00000000004 | 65.5 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 977 | P13863 | 303 | CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallu... | 213 | 0.00000000004 | 65.1 | 23 | 44 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 978 | Q8SSS9 | 1553 | QKGA_DICDI Probable serine/threonine-protein ... | 222 | 0.00000000004 | 66.2 | 27 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IMP:dictyBase. | 979 | Q8MY86 | 854 | FGFR1_DUGJA Fibroblast growth factor receptor... | 241 | 0.00000000004 | 65.9 | 24 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 980 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 212 | 0.00000000004 | 66.2 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 981 | Q9FJ54 | 439 | CIPKK_ARATH CBL-interacting serine/threonine-... | 247 | 0.00000000004 | 65.5 | 24 | 47 | GO:0005829; C:cytosol; TAS:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:TAIR. | | | | | | | | | | GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 982 | P43063 | 317 | CDK1_CANAL Cyclin-dependent kinase 1 OS=Candi... | 180 | 0.00000000004 | 65.1 | 24 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:CGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:CGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IGI:CGD. | 983 | Q00536 | 496 | CDK16_HUMAN Cyclin-dependent kinase 16 OS=Hom... | 171 | 0.00000000004 | 65.9 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 984 | Q552C6 | 635 | ZAK2_DICDI Dual specificity protein kinase za... | 175 | 0.00000002 | 57.4 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0010468; P:regulation of gene expression; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 985 | Q21734 | 784 | KS6A1_CAEEL Putative ribosomal protein S6 kin... | 218 | 0.0000005 | 53.5 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 986 | Q5R4K3 | 802 | KS6A5_PONAB Ribosomal protein S6 kinase alpha... | 149 | 0.000002 | 51.6 | 26 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 987 | P52332 | 1153 | JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mu... | 210 | 0.000006 | 50.4 | 23 | 45 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 988 | P23458 | 1154 | JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Ho... | 213 | 0.000007 | 50.1 | 23 | 45 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 989 | Q9R117 | 1180 | TYK2_MOUSE Non-receptor tyrosine-protein kina... | 222 | 0.0001 | 46.2 | 23 | 42 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 990 | Q62689 | 1132 | JAK2_RAT Tyrosine-protein kinase JAK2 OS=Ratt... | 219 | 0.004 | 41.6 | 21 | 40 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016363; C:nuclear matrix; IDA:RGD. | | | | | | | | | | GO:0033130; F:acetylcholine receptor binding; IPI:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035401; F:histone kinase activity (H3-Y41 specific); ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0051428; F:peptide hormone receptor binding; IPI:RGD.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0031702; F:type 1 angiotensin receptor binding; IPI:RGD. | | | | | | | | | | GO:0042977; P:activation of JAK2 kinase activity; ISS:UniProtKB.::GO:0000186; P:activation of MAPKK activity; IMP:RGD.::GO:0031103; P:axon regeneration; IMP:RGD.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:RGD.::GO:0009755; P:hormone-mediated signaling pathway; IDA:RGD.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:RGD.::GO:0060333; P:interferon-gamma-mediated signaling pathway; IDA:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.::GO:0031959; P:mineralocorticoid receptor signaling pathway; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:RGD.::GO:0050867; P:positive regulation of cell activation; IMP:RGD.::GO:0045597; P:positive regulation of cell differentiation; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0043388; P:positive regulation of DNA binding; IMP:RGD.::GO:0050729; P:positive regulation of inflammatory response; IMP:RGD.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.::GO:0032731; P:positive regulation of interleukin-1 beta production; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IMP:RGD.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0033194; P:response to hydroperoxide; IMP:RGD.::GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IMP:RGD.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IMP:RGD.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IMP:RGD. | 991 | O12990 | 1153 | JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Da... | 166 | 0.004 | 42 | 22 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. |