| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P12931 | 536 | SRC_HUMAN Proto-oncogene tyrosine-protein kin... | 211 | 4e-20 | 92.8 | 29 | 52 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 62 | Q9ES70 | 313 | NEK6_MOUSE Serine/threonine-protein kinase Ne... | 241 | 4e-20 | 90.5 | 29 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB. | 63 | Q8TDX7 | 302 | NEK7_HUMAN Serine/threonine-protein kinase Ne... | 232 | 5e-20 | 90.5 | 28 | 46 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 64 | P13406 | 537 | FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno... | 215 | 5e-20 | 92.4 | 29 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 65 | Q9HC98 | 313 | NEK6_HUMAN Serine/threonine-protein kinase Ne... | 241 | 5e-20 | 90.5 | 29 | 47 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 66 | Q9WUD9 | 536 | SRC_RAT Proto-oncogene tyrosine-protein kinas... | 211 | 5e-20 | 92.4 | 29 | 52 | GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050839; F:cell adhesion molecule binding; IPI:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD. | | | | | | | | | | GO:0032148; P:activation of protein kinase B activity; IMP:UniProtKB.::GO:0034332; P:adherens junction organization; IDA:RGD.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:RGD.::GO:0016337; P:cell-cell adhesion; IEP:RGD.::GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IEP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IDA:RGD.::GO:0045785; P:positive regulation of cell adhesion; IDA:RGD.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IMP:RGD.::GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0010907; P:positive regulation of glucose metabolic process; IMP:RGD.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; IDA:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0010641; P:positive regulation of platelet-derived growth factor receptor signaling pathway; IEP:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; IMP:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0001101; P:response to acid; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0009615; P:response to virus; IEP:RGD.::GO:0045056; P:transcytosis; IDA:RGD. | 67 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 240 | 5e-20 | 92 | 31 | 51 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 68 | O22042 | 651 | M3K3_ARATH Mitogen-activated protein kinase k... | 223 | 6e-20 | 92.8 | 27 | 49 | GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 69 | Q05609 | 821 | CTR1_ARATH Serine/threonine-protein kinase CT... | 232 | 6e-20 | 93.2 | 31 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0071281; P:cellular response to iron ion; IEP:TAIR.::GO:0009873; P:ethylene mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009686; P:gibberellin biosynthetic process; IMP:TAIR.::GO:0010105; P:negative regulation of ethylene mediated signaling pathway; TAS:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:2000069; P:regulation of post-embryonic root development; IMP:TAIR.::GO:2000035; P:regulation of stem cell division; IMP:TAIR.::GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IMP:TAIR.::GO:0009750; P:response to fructose stimulus; IMP:TAIR.::GO:0009744; P:response to sucrose stimulus; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; TAS:TAIR. | 70 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 217 | 6e-20 | 92 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 71 | P54759 | 998 | EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus ... | 239 | 6e-20 | 93.2 | 28 | 50 | GO:0030425; C:dendrite; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.::GO:0045499; F:chemorepellent activity; ISS:UniProtKB.::GO:0046875; F:ephrin receptor binding; IDA:RGD.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; ISS:UniProtKB. | 72 | Q15375 | 998 | EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo ... | 239 | 6e-20 | 93.2 | 28 | 50 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.::GO:0045499; F:chemorepellent activity; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; ISS:UniProtKB. | 73 | P27966 | 450 | RMIL_AVEVR Serine/threonine-protein kinase-tr... | 247 | 6e-20 | 91.7 | 27 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 74 | P42685 | 505 | FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo... | 217 | 7e-20 | 92 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 75 | Q4JIM5 | 1182 | ABL2_MOUSE Abelson tyrosine-protein kinase 2 ... | 247 | 7e-20 | 93.2 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB. | 76 | P06239 | 509 | LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo... | 209 | 8e-20 | 91.7 | 30 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.::GO:0042610; F:CD8 receptor binding; IPI:UniProtKB.::GO:0001948; F:glycoprotein binding; IPI:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; IEP:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; NAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0030217; P:T cell differentiation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 77 | P13116 | 532 | SRC2_XENLA Tyrosine-protein kinase Src-2 OS=X... | 215 | 8e-20 | 92 | 29 | 52 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 78 | P21709 | 976 | EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo ... | 247 | 9e-20 | 92.8 | 28 | 50 | GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB. | 79 | P00523 | 533 | SRC_CHICK Proto-oncogene tyrosine-protein kin... | 211 | 1e-19 | 91.7 | 30 | 52 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 80 | P16277 | 499 | BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ... | 240 | 1e-19 | 91.3 | 30 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 81 | P14085 | 557 | SRC_AVIST Tyrosine-protein kinase transformin... | 211 | 1e-19 | 91.3 | 30 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 82 | D3ZBE5 | 302 | NEK7_RAT Serine/threonine-protein kinase Nek7... | 232 | 1e-19 | 89 | 28 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | | 83 | Q9ES74 | 302 | NEK7_MOUSE Serine/threonine-protein kinase Ne... | 232 | 1e-19 | 89 | 28 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | | 84 | P29317 | 976 | EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo ... | 246 | 2e-19 | 92 | 28 | 49 | GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0046849; P:bone remodeling; ISS:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; ISS:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IDA:UniProtKB.::GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.::GO:0043535; P:regulation of blood vessel endothelial cell migration; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; IMP:UniProtKB.::GO:0070848; P:response to growth factor stimulus; IMP:UniProtKB. | 85 | P00521 | 746 | ABL_MLVAB Tyrosine-protein kinase transformin... | 247 | 2e-19 | 91.7 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 86 | Q54R58 | 918 | YTYK2_DICDI Probable tyrosine-protein kinase ... | 254 | 2e-19 | 92 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 87 | P14084 | 568 | SRC_AVISS Tyrosine-protein kinase transformin... | 211 | 2e-19 | 90.9 | 30 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 88 | A7MBB4 | 966 | M3K13_BOVIN Mitogen-activated protein kinase ... | 238 | 2e-19 | 91.7 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IEA:InterPro. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IEA:InterPro. | 89 | Q8T2I8 | 1167 | SEPA_DICDI Serine/threonine-protein kinase se... | 215 | 2e-19 | 91.7 | 30 | 49 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 90 | Q61772 | 998 | EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus m... | 239 | 2e-19 | 91.7 | 28 | 50 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; IMP:UniProtKB.::GO:0045499; F:chemorepellent activity; IDA:MGI.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; IMP:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:MGI.::GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; IDA:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI. | 91 | P15054 | 587 | SRC_AVIS2 Tyrosine-protein kinase transformin... | 211 | 2e-19 | 90.9 | 30 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | |
