| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | Q4R7T5 | 570 | CDKL2_MACFA Cyclin-dependent kinase-like 2 OS... | 258 | 0.0000000000002 | 72.4 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 542 | O15146 | 869 | MUSK_HUMAN Muscle, skeletal receptor tyrosine... | 251 | 0.0000000000002 | 72.8 | 25 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007613; P:memory; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.::GO:2000541; P:positive regulation of protein geranylgeranylation; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; ISS:UniProtKB.::GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 543 | Q9I8N6 | 977 | CSF1R_DANRE Macrophage colony-stimulating fac... | 152 | 0.0000000000003 | 72.8 | 31 | 55 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0048246; P:macrophage chemotaxis; IMP:ZFIN.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro.::GO:0050936; P:xanthophore differentiation; IMP:ZFIN. | 544 | Q55GE6 | 2615 | ROCO7_DICDI Probable serine/threonine-protein... | 260 | 0.0000000000003 | 73.2 | 25 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 545 | F1N9Y5 | 613 | KSYK_CHICK Tyrosine-protein kinase SYK OS=Gal... | 249 | 0.0000000000003 | 72.4 | 27 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032009; C:early phagosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IMP:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.::GO:0071226; P:cellular response to molecule of fungal origin; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0007159; P:leukocyte cell-cell adhesion; ISS:UniProtKB.::GO:0001945; P:lymph vessel development; ISS:UniProtKB.::GO:0002281; P:macrophage activation involved in immune response; ISS:UniProtKB.::GO:0002283; P:neutrophil activation involved in immune response; ISS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.::GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0090237; P:regulation of arachidonic acid secretion; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043313; P:regulation of neutrophil degranulation; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0032928; P:regulation of superoxide anion generation; ISS:UniProtKB.::GO:0002554; P:serotonin secretion by platelet; ISS:UniProtKB. | 546 | Q05030 | 1097 | PGFRB_RAT Platelet-derived growth factor rece... | 146 | 0.0000000000003 | 72.8 | 34 | 55 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0043202; C:lysosomal lumen; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0005019; F:platelet-derived growth factor beta-receptor activity; ISS:UniProtKB.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0060981; P:cell migration involved in coronary angiogenesis; ISS:UniProtKB.::GO:0035441; P:cell migration involved in vasculogenesis; ISS:UniProtKB.::GO:0006024; P:glycosaminoglycan biosynthetic process; IMP:RGD.::GO:0048839; P:inner ear development; IEP:RGD.::GO:0007243; P:intracellular protein kinase cascade; IMP:RGD.::GO:0072278; P:metanephric comma-shaped body morphogenesis; IEP:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0072262; P:metanephric glomerular mesangial cell proliferation involved in metanephros development; ISS:UniProtKB.::GO:0035789; P:metanephric mesenchymal cell migration; IDA:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; IEP:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IEP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0090280; P:positive regulation of calcium ion import; ISS:UniProtKB.::GO:0050921; P:positive regulation of chemotaxis; ISS:UniProtKB.::GO:0032967; P:positive regulation of collagen biosynthetic process; IMP:RGD.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0035793; P:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; ISS:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0034405; P:response to fluid shear stress; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:RGD.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro.::GO:0042060; P:wound healing; IEP:RGD. | 547 | Q9Z138 | 944 | ROR2_MOUSE Tyrosine-protein kinase transmembr... | 250 | 0.0000000000003 | 72.8 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005109; F:frizzled binding; IPI:BHF-UCL.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:MGI.::GO:0017147; F:Wnt-protein binding; IPI:MGI. | | | | | | | | | | GO:0001502; P:cartilage condensation; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0030538; P:embryonic genitalia morphogenesis; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0007254; P:JNK cascade; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0001756; P:somitogenesis; IMP:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.::GO:0007223; P:Wnt receptor signaling pathway, calcium modulating pathway; IPI:MGI.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IMP:MGI. | 548 | Q7YR43 | 909 | DDR1_PANTR Epithelial discoidin domain-contai... | 260 | 0.0000000000003 | 72.8 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0038062; F:protein tyrosine kinase collagen receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007595; P:lactation; IEA:UniProtKB-KW.::GO:0038083; P:peptidyl-tyrosine autophosphorylation; ISS:UniProtKB.::GO:0010715; P:regulation of extracellular matrix disassembly; ISS:UniProtKB.::GO:0014909; P:smooth muscle cell migration; ISS:UniProtKB.::GO:0061302; P:smooth muscle cell-matrix adhesion; ISS:UniProtKB.::GO:0044319; P:wound healing, spreading of cells; ISS:UniProtKB. | 549 | Q00944 | 1053 | FAK1_CHICK Focal adhesion kinase 1 OS=Gallus ... | 214 | 0.0000000000003 | 72.8 | 30 | 46 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 550 | P00529 | 402 | ROS_AVISU Tyrosine-protein kinase transformin... | 239 | 0.0000000000003 | 71.6 | 30 | 44 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 551 | Q9Z2A0 | 559 | PDPK1_MOUSE 3-phosphoinositide-dependent prot... | 231 | 0.0000000000003 | 72.4 | 24 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB. | 552 | Q9M1G3 | 669 | LRK16_ARATH Probable L-type lectin-domain con... | 191 | 0.0000000000003 | 72.4 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 553 | Q15131 | 360 | CDK10_HUMAN Cyclin-dependent kinase 10 OS=Hom... | 185 | 0.0000000000003 | 71.6 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc. | 554 | O55173 | 559 | PDPK1_RAT 3-phosphoinositide-dependent protei... | 231 | 0.0000000000003 | 72 | 24 | 48 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 555 | Q5R754 | 493 | CDKL2_PONAB Cyclin-dependent kinase-like 2 OS... | 258 | 0.0000000000003 | 72 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 556 | Q08345 | 913 | DDR1_HUMAN Epithelial discoidin domain-contai... | 260 | 0.0000000000003 | 72.4 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; IDA:UniProtKB.::GO:0038062; F:protein tyrosine kinase collagen receptor activity; IDA:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEA:UniProtKB-KW.::GO:0038083; P:peptidyl-tyrosine autophosphorylation; IDA:UniProtKB.::GO:0010715; P:regulation of extracellular matrix disassembly; IMP:UniProtKB.::GO:0014909; P:smooth muscle cell migration; IMP:UniProtKB.::GO:0061302; P:smooth muscle cell-matrix adhesion; IMP:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.::GO:0044319; P:wound healing, spreading of cells; IMP:UniProtKB. | 557 | P09619 | 1106 | PGFRB_HUMAN Platelet-derived growth factor re... | 209 | 0.0000000000003 | 72.4 | 28 | 46 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0043202; C:lysosomal lumen; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004992; F:platelet activating factor receptor activity; TAS:ProtInc.::GO:0005019; F:platelet-derived growth factor beta-receptor activity; IDA:UniProtKB.::GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.::GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060981; P:cell migration involved in coronary angiogenesis; ISS:UniProtKB.::GO:0035441; P:cell migration involved in vasculogenesis; ISS:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0072262; P:metanephric glomerular mesangial cell proliferation involved in metanephros development; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0090280; P:positive regulation of calcium ion import; ISS:UniProtKB.::GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0050921; P:positive regulation of chemotaxis; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0035793; P:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; IDA:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:BHF-UCL.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.::GO:0071670; P:smooth muscle cell chemotaxis; ISS:BHF-UCL.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 558 | Q6XKY3 | 357 | HOG1_HYPAT Mitogen-activated protein kinase h... | 210 | 0.0000000000003 | 71.2 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 559 | Q5XIT0 | 507 | CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R... | 264 | 0.0000000000003 | 72 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 560 | Q3UMM4 | 360 | CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus... | 187 | 0.0000000000003 | 71.2 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 561 | P38991 | 367 | IPL1_YEAST Spindle assembly checkpoint kinase... | 236 | 0.0000000000003 | 71.2 | 25 | 44 | GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD. | 562 | P13368 | 2554 | 7LESS_DROME Protein sevenless OS=Drosophila m... | 231 | 0.0000000000003 | 72.8 | 29 | 45 | GO:0005887; C:integral to plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:FlyBase. | | | | | | | | | | GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IMP:FlyBase.::GO:0045467; P:R7 cell development; NAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 563 | Q8WNU8 | 637 | NEK11_MACFA Serine/threonine-protein kinase N... | 153 | 0.0000000000003 | 72 | 31 | 52 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0031573; P:intra-S DNA damage checkpoint; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 564 | A8XJW8 | 494 | CST1_CAEBR Serine/threonine-protein kinase cs... | 165 | 0.0000000000003 | 71.6 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; ISS:UniProtKB.::GO:0048747; P:muscle fiber development; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 565 | P06784 | 515 | STE7_YEAST Serine/threonine-protein kinase ST... | 184 | 0.0000000000003 | 72 | 27 | 50 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071508; P:activation of MAPK activity involved in conjugation with cellular fusion; IDA:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0071507; P:MAPK cascade involved in conjugation with cellular fusion; IDA:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0010525; P:regulation of transposition, RNA-mediated; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD. | 566 | Q86I06 | 1123 | NEK3_DICDI Probable serine/threonine-protein ... | 239 | 0.0000000000003 | 72.4 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 567 | Q91147 | 729 | FGFR2_NOTVI Fibroblast growth factor receptor... | 262 | 0.0000000000004 | 72 | 27 | 44 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 568 | O73792 | 184 | TIE1_DANRE Tyrosine-protein kinase receptor T... | 155 | 0.0000000000004 | 68.9 | 34 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW. | 569 | P21803 | 821 | FGFR2_MOUSE Fibroblast growth factor receptor... | 258 | 0.0000000000004 | 72.4 | 26 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IMP:UniProtKB.::GO:0005576; C:extracellular region; TAS:MGI.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:MGI.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IGI:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0030282; P:bone mineralization; IMP:MGI.::GO:0060349; P:bone morphogenesis; IMP:MGI.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; IMP:MGI.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; IMP:MGI.::GO:0048755; P:branching morphogenesis of a nerve; IMP:MGI.::GO:0060449; P:bud elongation involved in lung branching; IMP:MGI.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0009880; P:embryonic pattern specification; IMP:MGI.::GO:0061031; P:endodermal digestive tract morphogenesis; IMP:MGI.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IMP:MGI.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; IMP:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; IMP:MGI.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; IMP:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; IMP:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; IMP:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0032808; P:lacrimal gland development; IMP:MGI.::GO:0060601; P:lateral sprouting from an epithelium; IMP:MGI.::GO:0070307; P:lens fiber cell development; IGI:MGI.::GO:0060174; P:limb bud formation; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0060463; P:lung lobe morphogenesis; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.::GO:0060615; P:mammary gland bud formation; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; IGI:MGI.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; IMP:MGI.::GO:0030901; P:midbrain development; IGI:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0045839; P:negative regulation of mitosis; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0042476; P:odontogenesis; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0003148; P:outflow tract septum morphogenesis; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051781; P:positive regulation of cell division; IMP:MGI.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IMP:MGI.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IGI:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IMP:MGI.::GO:0060523; P:prostate epithelial cord elongation; IMP:MGI.::GO:0021860; P:pyramidal neuron development; IMP:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IMP:MGI.::GO:0010453; P:regulation of cell fate commitment; IMP:MGI.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IMP:MGI.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0051150; P:regulation of smooth muscle cell differentiation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; IMP:MGI.::GO:0048489; P:synaptic vesicle transport; IMP:MGI.::GO:0001657; P:ureteric bud development; IGI:MGI.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI.::GO:0021847; P:ventricular zone neuroblast division; IMP:UniProtKB. | 570 | P16065 | 1125 | GCY_STRPU Speract receptor OS=Strongylocentro... | 249 | 0.0000000000004 | 72.4 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004383; F:guanylate cyclase activity; IEA:EC.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 571 | Q8VCT9 | 570 | TESK2_MOUSE Dual specificity testis-specific ... | 157 | 0.0000000000004 | 72 | 32 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. |
