| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | Q871M9 | 545 | BUR1_NEUCR Serine/threonine-protein kinase bu... | 208 | 0.00000000000009 | 73.6 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 482 | P26618 | 1089 | PGFRA_MOUSE Platelet-derived growth factor re... | 151 | 0.00000000000009 | 74.3 | 30 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:UniProtKB.::GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030325; P:adrenal gland development; IGI:MGI.::GO:0055003; P:cardiac myofibril assembly; IGI:UniProtKB.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0071230; P:cellular response to amino acid stimulus; IDA:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB.::GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:UniProtKB.::GO:0008210; P:estrogen metabolic process; IGI:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0060325; P:face morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0033327; P:Leydig cell differentiation; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0001553; P:luteinization; IMP:MGI.::GO:0030539; P:male genitalia development; IMP:MGI.::GO:0072277; P:metanephric glomerular capillary formation; IGI:UniProtKB.::GO:0010544; P:negative regulation of platelet activation; ISS:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000739; P:regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0061298; P:retina vasculature development in camera-type eye; IGI:UniProtKB.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI. | 483 | P79749 | 1048 | PGFRB_TAKRU Platelet-derived growth factor re... | 188 | 0.00000000000009 | 74.3 | 30 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0043202; C:lysosomal lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 484 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 262 | 0.00000000000009 | 74.3 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 485 | Q9Y4K4 | 846 | M4K5_HUMAN Mitogen-activated protein kinase k... | 245 | 0.0000000000001 | 73.9 | 27 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc. | 486 | Q9FG33 | 652 | LRKS5_ARATH Probable L-type lectin-domain con... | 267 | 0.0000000000001 | 73.9 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 487 | O88445 | 282 | AURKC_MOUSE Aurora kinase C OS=Mus musculus (... | 183 | 0.0000000000001 | 72 | 28 | 46 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 488 | Q55E58 | 3184 | PATS1_DICDI Probable serine/threonine-protein... | 261 | 0.0000000000001 | 74.3 | 23 | 46 | GO:0042641; C:actomyosin; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 489 | Q9WTR2 | 1291 | M3K6_MOUSE Mitogen-activated protein kinase k... | 201 | 0.0000000000001 | 74.3 | 32 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 490 | Q54PB4 | 481 | MYLKE_DICDI Probable myosin light chain kinas... | 225 | 0.0000000000001 | 73.2 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 491 | P09581 | 977 | CSF1R_MOUSE Macrophage colony-stimulating fac... | 151 | 0.0000000000001 | 73.9 | 29 | 54 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0043235; C:receptor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019955; F:cytokine binding; IDA:UniProtKB.::GO:0005011; F:macrophage colony-stimulating factor receptor activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL. | | | | | | | | | | GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0045124; P:regulation of bone resorption; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0031529; P:ruffle organization; IMP:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB. | 492 | Q6GPL3 | 368 | AUKBB_XENLA Aurora kinase B-B OS=Xenopus laev... | 233 | 0.0000000000001 | 72.8 | 27 | 46 | GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 493 | Q8AXY6 | 947 | MUSK_CHICK Muscle, skeletal receptor tyrosine... | 249 | 0.0000000000001 | 73.9 | 25 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0008582; P:regulation of synaptic growth at neuromuscular junction; ISS:UniProtKB. | 494 | P57097 | 994 | MERTK_RAT Tyrosine-protein kinase Mer OS=Ratt... | 251 | 0.0000000000001 | 73.9 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001750; C:photoreceptor outer segment; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:RGD. | | | | | | | | | | | 495 | P11802 | 303 | CDK4_HUMAN Cyclin-dependent kinase 4 OS=Homo ... | 189 | 0.0000000000001 | 72 | 31 | 49 | GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.::GO:0042493; P:response to drug; IGI:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome. | 496 | Q551H4 | 1028 | FRAY2_DICDI Serine/threonine-protein kinase f... | 235 | 0.0000000000001 | 73.9 | 24 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 497 | Q755C4 | 367 | IPL1_ASHGO Spindle assembly checkpoint kinase... | 230 | 0.0000000000001 | 72.8 | 23 | 43 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 498 | Q09639 | 707 | GRK2_CAEEL G protein-coupled receptor kinase ... | 179 | 0.0000000000001 | 73.6 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IMP:WormBase.::GO:0006972; P:hyperosmotic response; IMP:WormBase.::GO:0032501; P:multicellular organismal process; IGI:WormBase.::GO:0042048; P:olfactory behavior; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IGI:WormBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 499 | Q92772 | 493 | CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS... | 258 | 0.0000000000001 | 73.2 | 26 | 46 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007548; P:sex differentiation; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 500 | Q01974 | 943 | ROR2_HUMAN Tyrosine-protein kinase transmembr... | 250 | 0.0000000000001 | 73.6 | 27 | 44 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.::GO:0017147; F:Wnt-protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 501 | P24348 | 1323 | LET23_CAEEL Receptor tyrosine-protein kinase ... | 246 | 0.0000000000001 | 73.9 | 29 | 48 | GO:0016324; C:apical plasma membrane; IDA:WormBase.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 502 | Q64702 | 925 | PLK4_MOUSE Serine/threonine-protein kinase PL... | 193 | 0.0000000000001 | 73.6 | 25 | 48 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; IMP:UniProtKB. | 503 | Q9V6K3 | 724 | ROR2_DROME Tyrosine-protein kinase transmembr... | 244 | 0.0000000000001 | 73.6 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 504 | Q9FJI4 | 675 | LK111_ARATH Putative L-type lectin-domain con... | 168 | 0.0000000000001 | 73.6 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 505 | Q63474 | 910 | DDR1_RAT Epithelial discoidin domain-containi... | 260 | 0.0000000000001 | 73.6 | 28 | 43 | GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0038062; F:protein tyrosine kinase collagen receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007595; P:lactation; IEA:UniProtKB-KW.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0038083; P:peptidyl-tyrosine autophosphorylation; ISS:UniProtKB.::GO:0010715; P:regulation of extracellular matrix disassembly; ISS:UniProtKB.::GO:0043588; P:skin development; IEP:RGD.::GO:0014909; P:smooth muscle cell migration; ISS:UniProtKB.::GO:0061302; P:smooth muscle cell-matrix adhesion; ISS:UniProtKB.::GO:0044319; P:wound healing, spreading of cells; ISS:UniProtKB. | 506 | Q8BPM2 | 847 | M4K5_MOUSE Mitogen-activated protein kinase k... | 247 | 0.0000000000001 | 73.6 | 27 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 507 | Q4FZD7 | 595 | PLK5_MOUSE Inactive serine/threonine-protein ... | 220 | 0.0000000000001 | 73.2 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002357; P:defense response to tumor cell; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006927; P:transformed cell apoptotic process; IMP:UniProtKB. | 508 | Q03364 | 813 | FGFR2_XENLA Fibroblast growth factor receptor... | 258 | 0.0000000000001 | 73.6 | 26 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 509 | O43353 | 540 | RIPK2_HUMAN Receptor-interacting serine/threo... | 233 | 0.0000000000001 | 73.2 | 26 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050700; F:CARD domain binding; IPI:UniProtKB.::GO:0030274; F:LIM domain binding; IPI:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:ProtInc.::GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:MGI.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; IDA:MGI.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 510 | Q00495 | 978 | CSF1R_RAT Macrophage colony-stimulating facto... | 151 | 0.0000000000001 | 73.6 | 29 | 54 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019955; F:cytokine binding; ISS:UniProtKB.::GO:0005011; F:macrophage colony-stimulating factor receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; IDA:RGD.::GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IMP:RGD.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0045124; P:regulation of bone resorption; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0031529; P:ruffle organization; ISS:UniProtKB.::GO:0007519; P:skeletal muscle tissue development; IEP:RGD.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB. | 511 | Q91286 | 824 | FGFR2_PLEWA Fibroblast growth factor receptor... | 262 | 0.0000000000001 | 73.6 | 27 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0048730; P:epidermis morphogenesis; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0016331; P:morphogenesis of embryonic epithelium; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB. |
