| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | Q54XX5 | 848 | Y9849_DICDI Probable serine/threonine-protein... | 261 | 0.00000000000005 | 74.7 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 452 | C0LGQ9 | 1037 | Y4294_ARATH Probable LRR receptor-like serine... | 167 | 0.00000000000005 | 74.7 | 31 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 453 | Q9M3E5 | 682 | LRK11_ARATH Putative L-type lectin-domain con... | 176 | 0.00000000000005 | 74.7 | 30 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 454 | O88664 | 1001 | TAOK1_RAT Serine/threonine-protein kinase TAO... | 232 | 0.00000000000005 | 74.7 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030295; F:protein kinase activator activity; IMP:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB. | 455 | Q5F2E8 | 1001 | TAOK1_MOUSE Serine/threonine-protein kinase T... | 232 | 0.00000000000005 | 74.7 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 456 | Q7L7X3 | 1001 | TAOK1_HUMAN Serine/threonine-protein kinase T... | 232 | 0.00000000000005 | 74.7 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 457 | Q2QLE0 | 1381 | MET_PIG Hepatocyte growth factor receptor OS=... | 235 | 0.00000000000006 | 75.1 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 458 | Q9N0X0 | 344 | AURKB_PIG Aurora kinase B OS=Sus scrofa (Pig)... | 183 | 0.00000000000006 | 73.2 | 28 | 46 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 459 | C0LGI2 | 929 | Y1677_ARATH Probable LRR receptor-like serine... | 238 | 0.00000000000006 | 74.7 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 460 | Q5UPU3 | 546 | YL268_MIMIV Putative serine/threonine-protein... | 174 | 0.00000000000006 | 74.3 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 461 | B2GUY1 | 924 | PLK4_RAT Serine/threonine-protein kinase PLK4... | 193 | 0.00000000000006 | 74.7 | 25 | 48 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 462 | P54754 | 993 | EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus m... | 241 | 0.00000000000006 | 74.7 | 26 | 49 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; IDA:MGI.::GO:0005005; F:transmembrane-ephrin receptor activity; TAS:MGI. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0007413; P:axonal fasciculation; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0021952; P:central nervous system projection neuron axonogenesis; IDA:MGI.::GO:0022038; P:corpus callosum development; IMP:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IMP:UniProtKB.::GO:0048546; P:digestive tract morphogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048538; P:thymus development; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:UniProtKB. | 463 | P54753 | 998 | EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo ... | 241 | 0.00000000000006 | 74.7 | 26 | 49 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0022038; P:corpus callosum development; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0048546; P:digestive tract morphogenesis; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.::GO:0048538; P:thymus development; ISS:UniProtKB.::GO:0001655; P:urogenital system development; ISS:UniProtKB. | 464 | Q09YK0 | 1382 | MET_MUNMU Hepatocyte growth factor receptor O... | 235 | 0.00000000000006 | 74.7 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 465 | C0LGS2 | 1136 | Y4361_ARATH Probable LRR receptor-like serine... | 196 | 0.00000000000007 | 74.7 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 466 | A2VDZ4 | 893 | PLK4_BOVIN Serine/threonine-protein kinase PL... | 193 | 0.00000000000007 | 74.3 | 26 | 48 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 467 | O35346 | 1055 | FAK1_RAT Focal adhesion kinase 1 OS=Rattus no... | 214 | 0.00000000000007 | 74.7 | 30 | 46 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016604; C:nuclear body; IDA:RGD.::GO:0005730; C:nucleolus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030644; P:cellular chloride ion homeostasis; IMP:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; IEP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0030336; P:negative regulation of cell migration; IMP:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; IMP:RGD.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:RGD.::GO:0050766; P:positive regulation of phagocytosis; IMP:RGD.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0050806; P:positive regulation of synaptic transmission; IMP:RGD.::GO:0045909; P:positive regulation of vasodilation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 468 | P34556 | 332 | CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caeno... | 191 | 0.00000000000007 | 72.8 | 25 | 48 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IMP:UniProtKB.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0045836; P:positive regulation of meiosis; IMP:WormBase.::GO:0051446; P:positive regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0035046; P:pronuclear migration; IMP:WormBase. | 469 | B4KYX8 | 778 | PLK4_DROMO Serine/threonine-protein kinase PL... | 232 | 0.00000000000007 | 74.3 | 24 | 46 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 470 | P16234 | 1089 | PGFRA_HUMAN Platelet-derived growth factor re... | 151 | 0.00000000000007 | 74.7 | 30 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:UniProtKB.::GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:UniProtKB.::GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0001553; P:luteinization; ISS:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0010544; P:negative regulation of platelet activation; IDA:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0070527; P:platelet aggregation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.::GO:2000739; P:regulation of mesenchymal stem cell differentiation; IMP:UniProtKB.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 471 | P34152 | 1090 | FAK1_MOUSE Focal adhesion kinase 1 OS=Mus mus... | 214 | 0.00000000000007 | 74.7 | 30 | 46 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:MGI.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0040023; P:establishment of nucleus localization; IDA:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0051964; P:negative regulation of synapse assembly; IMP:MGI.::GO:0001764; P:neuron migration; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0001570; P:vasculogenesis; IMP:MGI. | 472 | P70218 | 827 | M4K1_MOUSE Mitogen-activated protein kinase k... | 236 | 0.00000000000007 | 74.3 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IDA:UniProtKB. | 473 | Q09YI9 | 1384 | MET_SHEEP Hepatocyte growth factor receptor O... | 216 | 0.00000000000008 | 74.7 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 474 | Q05397 | 1052 | FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sa... | 214 | 0.00000000000008 | 74.3 | 30 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IDA:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; TAS:UniProtKB.::GO:0007411; P:axon guidance; TAS:UniProtKB.::GO:0048870; P:cell motility; TAS:UniProtKB.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0009790; P:embryo development; TAS:UniProtKB.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0030010; P:establishment of cell polarity; TAS:UniProtKB.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0003007; P:heart morphogenesis; TAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0022408; P:negative regulation of cell-cell adhesion; IDA:BHF-UCL.::GO:0038007; P:netrin-activated signaling pathway; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0001890; P:placenta development; TAS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; TAS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; TAS:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 475 | P53667 | 647 | LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie... | 168 | 0.00000000000008 | 73.9 | 29 | 49 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 476 | Q96S53 | 571 | TESK2_HUMAN Dual specificity testis-specific ... | 158 | 0.00000000000008 | 73.9 | 33 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 477 | Q924U5 | 570 | TESK2_RAT Dual specificity testis-specific pr... | 157 | 0.00000000000008 | 73.9 | 33 | 54 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:UniProtKB. | 478 | P20786 | 1088 | PGFRA_RAT Platelet-derived growth factor rece... | 151 | 0.00000000000008 | 74.3 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB.::GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0042063; P:gliogenesis; IEP:RGD.::GO:0048839; P:inner ear development; IEP:RGD.::GO:0001553; P:luteinization; ISS:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0010544; P:negative regulation of platelet activation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000739; P:regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010035; P:response to inorganic substance; IEP:RGD.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB. | 479 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 238 | 0.00000000000008 | 73.9 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 480 | Q769I5 | 1384 | MET_BOVIN Hepatocyte growth factor receptor O... | 216 | 0.00000000000009 | 74.3 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 481 | Q871M9 | 545 | BUR1_NEUCR Serine/threonine-protein kinase bu... | 208 | 0.00000000000009 | 73.6 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | |
