| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q62270 | 496 | SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mu... | 226 | 6e-16 | 80.1 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 272 | Q924I2 | 873 | M4K3_RAT Mitogen-activated protein kinase kin... | 248 | 6e-16 | 80.9 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 273 | Q9NYL2 | 800 | MLTK_HUMAN Mitogen-activated protein kinase k... | 223 | 6e-16 | 80.9 | 29 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0007050; P:cell cycle arrest; IMP:UniProtKB.::GO:0008219; P:cell death; NAS:UniProtKB.::GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB. | 274 | B0LT89 | 431 | STK24_RAT Serine/threonine-protein kinase 24 ... | 241 | 6e-16 | 79.7 | 25 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0048680; P:positive regulation of axon regeneration; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 275 | O73798 | 1358 | IGF1R_XENLA Insulin-like growth factor 1 rece... | 240 | 7e-16 | 80.9 | 27 | 45 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005520; F:insulin-like growth factor binding; IDA:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001556; P:oocyte maturation; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB. | 276 | P08630 | 786 | BTKL_DROME Tyrosine-protein kinase Btk29A OS=... | 209 | 7e-16 | 80.5 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0045172; C:germline ring canal; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.::GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007619; P:courtship behavior; NAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0007301; P:female germline ring canal formation; IDA:UniProtKB.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007485; P:imaginal disc-derived male genitalia development; IMP:UniProtKB.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0046960; P:sensitization; IMP:FlyBase. | 277 | Q62413 | 1035 | EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus m... | 191 | 7e-16 | 80.9 | 29 | 52 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro. | | | | | | | | | | | 278 | Q61UC4 | 811 | KRAF1_CAEBR Raf homolog serine/threonine-prot... | 217 | 8e-16 | 80.5 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 279 | Q9SCT4 | 836 | IMK2_ARATH Probably inactive leucine-rich rep... | 247 | 9e-16 | 80.5 | 25 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 280 | O59790 | 355 | ARK1_SCHPO Serine/threonine-protein kinase ar... | 237 | 9e-16 | 78.6 | 25 | 45 | GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase. | 281 | P00544 | 545 | FGR_FSVGR Tyrosine-protein kinase transformin... | 211 | 9e-16 | 79.7 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 282 | Q13882 | 451 | PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo ... | 242 | 0.000000000000001 | 79.3 | 28 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB. | 283 | Q99JP0 | 894 | M4K3_MOUSE Mitogen-activated protein kinase k... | 248 | 0.000000000000001 | 80.5 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 284 | P08069 | 1367 | IGF1R_HUMAN Insulin-like growth factor 1 rece... | 241 | 0.000000000000001 | 80.5 | 28 | 46 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043559; F:insulin binding; IPI:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0006955; P:immune response; IMP:BHF-UCL.::GO:0051389; P:inactivation of MAPKK activity; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IC:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB. | 285 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 228 | 0.000000000000001 | 79 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 286 | Q62190 | 1378 | RON_MOUSE Macrophage-stimulating protein rece... | 246 | 0.000000000000001 | 80.5 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0009615; P:response to virus; IMP:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 287 | Q07292 | 813 | KRAF1_CAEEL Raf homolog serine/threonine-prot... | 217 | 0.000000000000001 | 80.1 | 27 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007265; P:Ras protein signal transduction; IGI:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 288 | Q00993 | 888 | UFO_MOUSE Tyrosine-protein kinase receptor UF... | 227 | 0.000000000000001 | 80.1 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IGI:UniProtKB.::GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0031668; P:cellular response to extracellular stimulus; IDA:MGI.::GO:0007167; P:enzyme linked receptor protein signaling pathway; IGI:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0021885; P:forebrain cell migration; IGI:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IGI:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0042698; P:ovulation cycle; IGI:MGI.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.::GO:0032940; P:secretion by cell; IMP:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI. | 289 | Q8IVH8 | 894 | M4K3_HUMAN Mitogen-activated protein kinase k... | 248 | 0.000000000000001 | 80.1 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc. | 290 | Q66L42 | 940 | M3K10_MOUSE Mitogen-activated protein kinase ... | 247 | 0.000000000000001 | 80.1 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 291 | Q39008 | 608 | M3K1_ARATH Mitogen-activated protein kinase k... | 233 | 0.000000000000001 | 79.7 | 27 | 43 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0019900; F:kinase binding; IPI:TAIR.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IDA:TAIR. | 292 | Q60855 | 656 | RIPK1_MOUSE Receptor-interacting serine/threo... | 246 | 0.000000000000001 | 79.7 | 25 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 293 | P20806 | 2594 | 7LESS_DROVI Protein sevenless OS=Drosophila v... | 256 | 0.000000000000001 | 80.5 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 294 | P29319 | 983 | EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus m... | 238 | 0.000000000000001 | 80.1 | 26 | 48 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0003197; P:endocardial cushion development; IMP:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; IMP:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 295 | Q8BKG3 | 1062 | PTK7_MOUSE Inactive tyrosine-protein kinase 7... | 237 | 0.000000000000001 | 80.1 | 28 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | GO:0003401; P:axis elongation; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0060026; P:convergent extension; IMP:MGI.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:MGI.::GO:0001736; P:establishment of planar polarity; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 296 | Q66HA1 | 850 | M3K11_RAT Mitogen-activated protein kinase ki... | 198 | 0.000000000000001 | 79.7 | 28 | 51 | GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IPI:RGD. | | | | | | | | | | GO:0008219; P:cell death; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 297 | Q60751 | 1373 | IGF1R_MOUSE Insulin-like growth factor 1 rece... | 242 | 0.000000000000001 | 80.1 | 28 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:MGI.::GO:0031017; P:exocrine pancreas development; IMP:MGI.::GO:0030238; P:male sex determination; IMP:MGI.::GO:0030879; P:mammary gland development; IMP:MGI.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB. | 298 | O70405 | 1051 | ULK1_MOUSE Serine/threonine-protein kinase UL... | 198 | 0.000000000000001 | 79.7 | 28 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.::GO:0048675; P:axon extension; IMP:MGI.::GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0021933; P:radial glia guided migration of cerebellar granule cell; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0051386; P:regulation of nerve growth factor receptor signaling pathway; IMP:MGI. | 299 | Q16584 | 847 | M3K11_HUMAN Mitogen-activated protein kinase ... | 198 | 0.000000000000001 | 79.7 | 28 | 51 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:UniProtKB.::GO:0007017; P:microtubule-based process; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 300 | Q9Y2U5 | 619 | M3K2_HUMAN Mitogen-activated protein kinase k... | 237 | 0.000000000000002 | 79.3 | 26 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 301 | Q80XI6 | 850 | M3K11_MOUSE Mitogen-activated protein kinase ... | 198 | 0.000000000000002 | 79.7 | 28 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | |
