| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P51956 | 506 | NEK3_HUMAN Serine/threonine-protein kinase Ne... | 240 | 1e-17 | 85.5 | 27 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB. | 182 | P05625 | 647 | RAF1_CHICK RAF proto-oncogene serine/threonin... | 246 | 1e-17 | 85.9 | 24 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 183 | Q08881 | 620 | ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=... | 237 | 1e-17 | 85.9 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 184 | A8X775 | 857 | DLK1_CAEBR Mitogen-activated protein kinase k... | 192 | 1e-17 | 86.3 | 30 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 185 | O09127 | 1004 | EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus m... | 236 | 1e-17 | 86.3 | 29 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016322; P:neuron remodeling; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. | 186 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 195 | 1e-17 | 85.9 | 30 | 52 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 187 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 210 | 1e-17 | 85.9 | 30 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 188 | Q03526 | 625 | ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=... | 237 | 1e-17 | 85.5 | 27 | 46 | GO:0005829; C:cytosol; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IMP:MGI.::GO:0032633; P:interleukin-4 production; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001865; P:NK T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. | 189 | Q99683 | 1374 | M3K5_HUMAN Mitogen-activated protein kinase k... | 220 | 1e-17 | 86.3 | 30 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.::GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 190 | A7E3S4 | 648 | RAF1_BOVIN RAF proto-oncogene serine/threonin... | 246 | 1e-17 | 85.5 | 24 | 46 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 191 | P27636 | 974 | CDC15_YEAST Cell division control protein 15 ... | 221 | 1e-17 | 85.9 | 28 | 47 | GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005816; C:spindle pole body; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:SGD.::GO:0007138; P:meiotic anaphase II; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD. | 192 | P04627 | 604 | ARAF_MOUSE Serine/threonine-protein kinase A-... | 250 | 1e-17 | 85.5 | 27 | 47 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 193 | P14056 | 604 | ARAF_RAT Serine/threonine-protein kinase A-Ra... | 250 | 1e-17 | 85.5 | 27 | 47 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 194 | O35099 | 1380 | M3K5_MOUSE Mitogen-activated protein kinase k... | 220 | 2e-17 | 85.9 | 30 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 195 | Q60750 | 977 | EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus m... | 208 | 2e-17 | 85.9 | 29 | 50 | GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. | 196 | Q55EC7 | 960 | GEFX_DICDI RasGEF domain-containing serine/th... | 249 | 2e-17 | 85.5 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 197 | Q55A09 | 1331 | Y9963_DICDI Probable serine/threonine-protein... | 249 | 2e-17 | 85.9 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 198 | P29320 | 983 | EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo ... | 239 | 2e-17 | 85.5 | 27 | 50 | GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; IDA:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB. | 199 | Q99N57 | 648 | RAF1_MOUSE RAF proto-oncogene serine/threonin... | 246 | 2e-17 | 84.7 | 24 | 46 | GO:0005829; C:cytosol; TAS:MGI.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI. | 200 | Q55CA6 | 635 | Y0146_DICDI Probable serine/threonine-protein... | 178 | 2e-17 | 84.7 | 31 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 201 | Q98949 | 873 | TYRO3_CHICK Tyrosine-protein kinase receptor ... | 246 | 2e-17 | 85.1 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 202 | Q91571 | 985 | EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xen... | 250 | 3e-17 | 85.1 | 28 | 49 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0031589; P:cell-substrate adhesion; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB. | 203 | P42687 | 497 | SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D... | 215 | 3e-17 | 84.3 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 204 | O08680 | 984 | EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus ... | 239 | 4e-17 | 84.7 | 26 | 49 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0001660; P:fever generation; IEP:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD. | 205 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 214 | 4e-17 | 84.3 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 206 | Q55CY9 | 1326 | GDT8_DICDI Probable serine/threonine-protein ... | 248 | 4e-17 | 84.7 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 207 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 208 | 5e-17 | 83.6 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 208 | P70600 | 1009 | FAK2_RAT Protein-tyrosine kinase 2-beta OS=Ra... | 242 | 5e-17 | 84.3 | 27 | 47 | GO:0030424; C:axon; IDA:RGD.::GO:0005938; C:cell cortex; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0043423; F:3-phosphoinositide-dependent protein kinase binding; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0042976; P:activation of Janus kinase activity; IMP:RGD.::GO:0032863; P:activation of Rac GTPase activity; IMP:RGD.::GO:0043534; P:blood vessel endothelial cell migration; IMP:RGD.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0014009; P:glial cell proliferation; IEP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; IMP:RGD.::GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0001556; P:oocyte maturation; IMP:RGD.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IEP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:RGD.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IPI:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0043149; P:stress fiber assembly; IMP:RGD. | 209 | P28693 | 1004 | EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallu... | 241 | 6e-17 | 84.3 | 27 | 50 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB. | 210 | Q8LST2 | 557 | WNK7_ARATH Probable serine/threonine-protein ... | 182 | 6e-17 | 83.6 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 211 | O19004 | 606 | ARAF_PIG Serine/threonine-protein kinase A-Ra... | 251 | 6e-17 | 83.6 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |
