| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6PFQ7 | 802 | RASL2_MOUSE Ras GTPase-activating protein 4 O... | 236 | 0.00000000002 | 71.2 | 27 | 48 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 32 | Q86YV0 | 1011 | RASL3_HUMAN RAS protein activator like-3 OS=H... | 121 | 0.00000000002 | 71.2 | 36 | 52 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro. | 33 | Q8T498 | 1580 | GAP2_DROME Probable Ras GTPase-activating pro... | 219 | 0.0000000001 | 69.3 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 34 | P18963 | 3092 | IRA1_YEAST Inhibitory regulator protein IRA1 ... | 260 | 0.0000000002 | 68.2 | 24 | 46 | GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IMP:SGD. | | | | | | | | | | GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:SGD.::GO:0045761; P:regulation of adenylate cyclase activity; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 35 | A2RV61 | 1452 | GAPD1_XENLA GTPase-activating protein and VPS... | 387 | 0.0000000004 | 67.4 | 24 | 44 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 36 | Q8MLZ5 | 1207 | GAP2_CAEEL Ras GTPase-activating protein gap-... | 220 | 0.000000001 | 65.9 | 26 | 44 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; NAS:UniProtKB. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IEP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 37 | P19158 | 3079 | IRA2_YEAST Inhibitory regulator protein IRA2 ... | 281 | 0.000000003 | 64.7 | 23 | 44 | GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 38 | P33314 | 1104 | BUD2_YEAST Inhibitory regulator protein BUD2/... | 213 | 0.00000004 | 60.8 | 26 | 43 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0030447; P:filamentous growth; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 39 | Q14C86 | 1478 | GAPD1_HUMAN GTPase-activating protein and VPS... | 303 | 0.0000001 | 59.3 | 23 | 44 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 40 | Q6PAR5 | 1458 | GAPD1_MOUSE GTPase-activating protein and VPS... | 303 | 0.0000001 | 58.9 | 23 | 43 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 41 | A5D794 | 1413 | GAPD1_BOVIN GTPase-activating protein and VPS... | 303 | 0.0000002 | 58.5 | 23 | 44 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 42 | P48423 | 1163 | GAP1_DROME GTPase-activating protein OS=Droso... | 196 | 0.000006 | 53.5 | 25 | 39 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IMP:FlyBase. | | | | | | | | | | GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IMP:FlyBase.::GO:0007062; P:sister chromatid cohesion; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase. | 43 | Q60790 | 834 | RASA3_MOUSE Ras GTPase-activating protein 3 O... | 238 | 0.00002 | 51.6 | 23 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 44 | Q14644 | 834 | RASA3_HUMAN Ras GTPase-activating protein 3 O... | 240 | 0.00004 | 51.2 | 23 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 45 | Q9QYJ2 | 834 | RASA3_RAT Ras GTPase-activating protein 3 OS=... | 238 | 0.00004 | 50.8 | 23 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 46 | P58069 | 848 | RASA2_MOUSE Ras GTPase-activating protein 2 O... | 242 | 0.00004 | 50.8 | 24 | 39 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 47 | Q63713 | 847 | RASA2_RAT Ras GTPase-activating protein 2 OS=... | 254 | 0.0001 | 49.7 | 23 | 38 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 48 | Q28013 | 834 | RASA3_BOVIN Ras GTPase-activating protein 3 O... | 238 | 0.0003 | 48.1 | 23 | 39 | GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome. | 49 | Q29HW3 | 1774 | RME6_DROPS Receptor-mediated endocytosis prot... | 292 | 0.0004 | 47.8 | 25 | 43 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 50 | Q15283 | 849 | RASA2_HUMAN Ras GTPase-activating protein 2 O... | 85 | 0.0005 | 47.4 | 33 | 49 | GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 51 | Q9VZ08 | 1712 | RME6_DROME Receptor-mediated endocytosis prot... | 277 | 0.005 | 44.3 | 23 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 52 | Q9GYH7 | 1093 | RME6_CAEEL Receptor-mediated endocytosis prot... | 297 | 0.016 | 42.4 | 19 | 40 | GO:0045334; C:clathrin-coated endocytic vesicle; IDA:WormBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:WormBase. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IGI:WormBase.::GO:0032851; P:positive regulation of Rab GTPase activity; IGI:WormBase.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IMP:WormBase.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 53 | A8WVM4 | 1104 | RME6_CAEBR Receptor-mediated endocytosis prot... | 292 | 0.08 | 40 | 18 | 40 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 54 | B1W4A6 | 90 | HIS2_STRGG Phosphoribosyl-ATP pyrophosphatase... | 76 | 2.4 | 32.7 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. | 55 | Q9P782 | 336 | YNY8_SCHPO Uncharacterized protein C1711.08 O... | 145 | 2.5 | 35 | 26 | 40 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0001671; F:ATPase activator activity; ISS:PomBase.::GO:0051087; F:chaperone binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; ISS:PomBase. | | | | | | | | | | GO:0033554; P:cellular response to stress; ISS:PomBase.::GO:0006457; P:protein folding; ISS:PomBase. | 56 | Q22720 | 629 | GAP1_CAEEL Ras GTPase-activating protein gap-... | 144 | 3.2 | 35 | 30 | 47 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; NAS:UniProtKB. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IEP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 57 | Q9EWK0 | 90 | HIS2_STRCO Phosphoribosyl-ATP pyrophosphatase... | 68 | 3.7 | 32 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. | 58 | Q827L8 | 90 | HIS2_STRAW Phosphoribosyl-ATP pyrophosphatase... | 68 | 9.5 | 30.8 | 32 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004636; F:phosphoribosyl-ATP diphosphatase activity; IEA:EC. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. | 59 | A0JPI9 | 479 | CN16B_RAT Uncharacterized protein C14orf166B ... | 83 | 9.8 | 33.1 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | |
