| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O60020 | 405 | ASPR1_PHARH Aspartic protease OS=Phaffia rhod... | 336 | 3e-26 | 114 | 31 | 46 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 2 | P24268 | 407 | CATD_RAT Cathepsin D OS=Rattus norvegicus (Ra... | 344 | 6e-21 | 99 | 28 | 46 | GO:0005764; C:lysosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEP:RGD.::GO:0006508; P:proteolysis; IDA:RGD. | 3 | Q03168 | 387 | ASPP_AEDAE Lysosomal aspartic protease OS=Aed... | 349 | 2e-20 | 97.1 | 28 | 44 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | P18242 | 410 | CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse... | 346 | 2e-19 | 94.4 | 28 | 44 | GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI. | 5 | P80209 | 390 | CATD_BOVIN Cathepsin D OS=Bos taurus (Bovine)... | 394 | 3e-19 | 93.6 | 28 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | Q05744 | 398 | CATD_CHICK Cathepsin D OS=Gallus gallus (Chic... | 335 | 3e-19 | 93.6 | 27 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 7 | Q805F3 | 397 | CATEA_XENLA Cathepsin E-A OS=Xenopus laevis (... | 348 | 4e-19 | 93.2 | 28 | 45 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 348 | 1e-18 | 92 | 28 | 43 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 9 | Q4WNV0 | 474 | CTSD_ASPFU Aspartic-type endopeptidase ctsD O... | 413 | 1e-18 | 92.4 | 26 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q4LAL9 | 410 | CATD_CANFA Cathepsin D OS=Canis familiaris (D... | 351 | 6e-18 | 90.1 | 26 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q800A0 | 397 | CATE_LITCT Cathepsin E OS=Lithobates catesbei... | 337 | 6e-18 | 89.7 | 28 | 44 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 12 | Q805F2 | 397 | CATEB_XENLA Cathepsin E-B OS=Xenopus laevis (... | 348 | 7e-18 | 89.4 | 27 | 44 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | O76856 | 383 | CATD_DICDI Cathepsin D OS=Dictyostelium disco... | 398 | 1e-17 | 89 | 26 | 42 | GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | O93428 | 396 | CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu... | 333 | 1e-17 | 89 | 28 | 42 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 15 | Q28057 | 376 | PAG2_BOVIN Pregnancy-associated glycoprotein ... | 339 | 1e-17 | 88.2 | 27 | 43 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | Q9DEX3 | 396 | CATD_CLUHA Cathepsin D OS=Clupea harengus (At... | 400 | 1e-17 | 88.6 | 26 | 41 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | P70269 | 397 | CATE_MOUSE Cathepsin E OS=Mus musculus (Mouse... | 345 | 2e-17 | 87.8 | 29 | 44 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 18 | P16228 | 398 | CATE_RAT Cathepsin E OS=Rattus norvegicus (Ra... | 347 | 4e-17 | 87 | 29 | 45 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | Q9GMY7 | 386 | PEPA_RHIFE Pepsin A OS=Rhinolophus ferrumequi... | 343 | 4e-17 | 87 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | Q9MZS8 | 365 | CATD_SHEEP Cathepsin D OS=Ovis aries (Sheep).... | 332 | 1e-16 | 85.5 | 27 | 43 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | Q9D7R7 | 392 | PEPC_MOUSE Gastricsin OS=Mus musculus (Mouse)... | 361 | 1e-16 | 85.9 | 29 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | C5FZ57 | 430 | Y7979_ARTOC Putative aspergillopepsin A-like ... | 333 | 2e-16 | 85.9 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | O96009 | 420 | NAPSA_HUMAN Napsin-A OS=Homo sapiens (Human).... | 366 | 3e-16 | 85.1 | 29 | 43 | GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.::GO:0043129; P:surfactant homeostasis; IDA:UniProtKB. | 24 | P14091 | 401 | CATE_HUMAN Cathepsin E OS=Homo sapiens (Human... | 352 | 6e-16 | 83.6 | 29 | 45 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | Q9TSZ1 | 400 | RENI_CALJA Renin OS=Callithrix jacchus (White... | 406 | 8e-16 | 83.2 | 25 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | P81497 | 387 | PEPA_SUNMU Pepsin A OS=Suncus murinus (Asian ... | 418 | 0.000000000000002 | 82.4 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 27 | Q6DYE7 | 403 | RENI_CANFA Renin OS=Canis familiaris (Dog) (C... | 430 | 0.000000000000002 | 82.4 | 25 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | Q9GMY4 | 389 | PEPC_SORUN Gastricsin OS=Sorex unguiculatus (... | 335 | 0.000000000000004 | 81.3 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 29 | P43159 | 396 | CATE_RABIT Cathepsin E OS=Oryctolagus cunicul... | 348 | 0.000000000000004 | 81.3 | 28 | 44 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P04073 | 392 | PEPC_RAT Gastricsin OS=Rattus norvegicus (Rat... | 336 | 0.000000000000006 | 80.5 | 27 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q29078 | 389 | PAG1_PIG Pregnancy-associated glycoprotein 1 ... | 332 | 0.000000000000006 | 80.5 | 26 | 43 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
