| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q0P595 | 400 | SIR7_BOVIN NAD-dependent protein deacetylase ... | 127 | 0.00005 | 49.7 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB. | 122 | Q8PQK3 | 293 | NPD_XANAC NAD-dependent protein deacetylase O... | 122 | 0.00005 | 48.9 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 123 | Q89EA6 | 273 | NPD2_BRAJA NAD-dependent protein deacetylase ... | 169 | 0.00009 | 48.1 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 124 | Q9VAQ1 | 771 | SIR7_DROME NAD-dependent protein deacetylase ... | 127 | 0.0001 | 48.9 | 28 | 43 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 125 | Q9Y6E7 | 314 | SIR4_HUMAN NAD-dependent protein deacetylase ... | 308 | 0.0001 | 48.1 | 26 | 39 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 126 | Q94AQ6 | 373 | SIR4_ARATH NAD-dependent protein deacetylase ... | 214 | 0.0002 | 47.8 | 21 | 37 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0031348; P:negative regulation of defense response; IMP:TAIR.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 127 | Q9CM50 | 234 | NPD_PASMU NAD-dependent protein deacylase OS=... | 113 | 0.0002 | 47 | 33 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 128 | B0RM75 | 293 | NPD_XANCB NAD-dependent protein deacetylase O... | 112 | 0.0002 | 47 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 129 | Q8PDM9 | 293 | NPD_XANCP NAD-dependent protein deacetylase O... | 110 | 0.0003 | 47 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 130 | Q4UZX0 | 293 | NPD_XANC8 NAD-dependent protein deacetylase O... | 110 | 0.0003 | 47 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 131 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 133 | 0.0003 | 46.6 | 25 | 44 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 132 | O58669 | 249 | NPD_PYRHO NAD-dependent protein deacylase OS=... | 119 | 0.0004 | 46.2 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 133 | Q73WM7 | 237 | NPD_MYCPA NAD-dependent protein deacylase OS=... | 108 | 0.0004 | 45.8 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 134 | A8NWP2 | 299 | SIR5_COPC7 NAD-dependent protein deacylase OS... | 314 | 0.0004 | 46.2 | 25 | 34 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 135 | Q9UZE7 | 250 | NPD_PYRAB NAD-dependent protein deacylase OS=... | 117 | 0.0004 | 45.8 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0017136; F:NAD-dependent histone deacetylase activity; IEA:HAMAP.::GO:0008270; F:zinc ion binding; IEA:HAMAP. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 136 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 120 | 0.0004 | 46.2 | 29 | 50 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 137 | Q9RL35 | 299 | NPD1_STRCO NAD-dependent protein deacetylase ... | 120 | 0.0005 | 45.8 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 138 | Q8N6T7 | 355 | SIR6_HUMAN NAD-dependent protein deacetylase ... | 133 | 0.0007 | 45.8 | 25 | 41 | GO:0005724; C:nuclear telomeric heterochromatin; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:BHF-UCL.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB. | 139 | Q8R216 | 333 | SIR4_MOUSE NAD-dependent protein deacetylase ... | 120 | 0.0008 | 45.4 | 28 | 51 | GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 140 | E1BRE2 | 309 | SIR5_CHICK NAD-dependent protein deacylase si... | 139 | 0.0009 | 45.4 | 22 | 42 | | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 141 | P59941 | 334 | SIR6_MOUSE NAD-dependent protein deacetylase ... | 133 | 0.001 | 45.1 | 24 | 42 | GO:0005724; C:nuclear telomeric heterochromatin; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB. | 142 | Q8ELR0 | 236 | NPD_OCEIH NAD-dependent protein deacetylase O... | 111 | 0.003 | 43.5 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 143 | Q57YZ9 | 306 | SIR4_TRYB2 NAD-dependent protein deacetylase ... | 183 | 0.003 | 43.5 | 24 | 37 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 144 | Q95Q89 | 292 | SIR24_CAEEL NAD-dependent protein deacetylase... | 116 | 0.004 | 43.1 | 27 | 44 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 145 | O25849 | 229 | NPD_HELPY NAD-dependent protein deacylase OS=... | 109 | 0.005 | 42.4 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 146 | Q20480 | 287 | SIR41_CAEEL NAD-dependent protein deacetylase... | 120 | 0.005 | 42.7 | 27 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase. | 147 | Q8F3Z6 | 246 | NPD_LEPIN NAD-dependent protein deacylase OS=... | 268 | 0.005 | 42.4 | 23 | 34 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 148 | Q9ZAB8 | 208 | NPD_AGGAC NAD-dependent protein deacylase OS=... | 105 | 0.006 | 42 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 149 | Q5HZN8 | 309 | SIR5A_XENLA NAD-dependent protein deacylase s... | 133 | 0.006 | 42.7 | 26 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 150 | F7DKV7 | 309 | SIR5_XENTR NAD-dependent protein deacylase si... | 133 | 0.006 | 42.7 | 26 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 151 | Q72RR0 | 246 | NPD_LEPIC NAD-dependent protein deacylase OS=... | 268 | 0.007 | 42 | 23 | 33 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |
