| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O15056 | 1496 | SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens (H... | 194 | 1e-23 | 110 | 32 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 2 | Q9D2G5 | 1434 | SYNJ2_MOUSE Synaptojanin-2 OS=Mus musculus (M... | 176 | 8e-23 | 108 | 34 | 52 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 3 | O55207 | 1496 | SYNJ2_RAT Synaptojanin-2 OS=Rattus norvegicus... | 194 | 1e-22 | 107 | 31 | 51 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0005881; C:cytoplasmic microtubule; IDA:RGD.::GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0032587; C:ruffle membrane; IDA:RGD. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0052744; F:phosphatidylinositol monophosphate phosphatase activity; IDA:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:RGD.::GO:0048312; P:intracellular distribution of mitochondria; IDA:RGD.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 4 | Q9JII1 | 647 | INP5E_MOUSE 72 kDa inositol polyphosphate 5-p... | 32 | 2.3 | 35 | 50 | 69 | GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 5 | A0FI79 | 644 | INP5E_PANTR 72 kDa inositol polyphosphate 5-p... | 32 | 5.7 | 33.9 | 47 | 69 | GO:0035085; C:cilium axoneme; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 6 | Q9NRR6 | 644 | INP5E_HUMAN 72 kDa inositol polyphosphate 5-p... | 32 | 5.7 | 33.9 | 47 | 69 | GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 7 | Q9WVR1 | 647 | INP5E_RAT 72 kDa inositol polyphosphate 5-pho... | 32 | 2.4 | 35 | 50 | 69 | GO:0035085; C:cilium axoneme; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IMP:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0010976; P:positive regulation of neuron projection development; IMP:RGD. | 8 | Q9FUR2 | 646 | IP5P2_ARATH Type I inositol 1,4,5-trisphospha... | 101 | 4.3 | 34.3 | 29 | 45 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009845; P:seed germination; IMP:TAIR. | 9 | Q2I6J0 | 1226 | SHP2B_DANRE Phosphatidylinositol 3,4,5-trisph... | 106 | 5.4 | 34.3 | 28 | 41 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 10 | Q9LR47 | 617 | IP5P3_ARATH Type I inositol 1,4,5-trisphospha... | 101 | 0.45 | 37.4 | 33 | 44 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0010588; P:cotyledon vascular tissue pattern formation; IMP:TAIR.::GO:0046855; P:inositol phosphate dephosphorylation; IMP:TAIR.::GO:0048016; P:inositol phosphate-mediated signaling; IC:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IMP:TAIR.::GO:0010305; P:leaf vascular tissue pattern formation; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0010067; P:procambium histogenesis; IMP:TAIR. | 11 | O43426 | 1573 | SYNJ1_HUMAN Synaptojanin-1 OS=Homo sapiens (H... | 176 | 4e-19 | 96.3 | 30 | 49 | | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 12 | Q8CHC4 | 1574 | SYNJ1_MOUSE Synaptojanin-1 OS=Mus musculus (M... | 176 | 5e-19 | 96.3 | 30 | 49 | GO:0030118; C:clathrin coat; TAS:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI.::GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. | 13 | Q62910 | 1574 | SYNJ1_RAT Synaptojanin-1 OS=Rattus norvegicus... | 176 | 5e-19 | 96.3 | 30 | 49 | GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0014015; P:positive regulation of gliogenesis; IMP:RGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0032526; P:response to retinoic acid; IMP:RGD. | 14 | Q2I6J1 | 1266 | SHP2A_DANRE Phosphatidylinositol 3,4,5-trisph... | 15 | 4.1 | 34.7 | 80 | 87 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IMP:ZFIN.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IMP:ZFIN.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 15 | P32019 | 993 | I5P2_HUMAN Type II inositol 1,4,5-trisphospha... | 19 | 0.38 | 37.7 | 68 | 84 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 16 | O15357 | 1258 | SHIP2_HUMAN Phosphatidylinositol 3,4,5-trisph... | 15 | 4.4 | 34.7 | 80 | 87 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:UniProtKB.::GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 17 | Q84MA2 | 590 | IP5P1_ARATH Type I inositol 1,4,5-trisphospha... | 185 | 2e-18 | 93.2 | 29 | 56 | | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0032957; P:inositol trisphosphate metabolic process; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 18 | O18964 | 1324 | SYNJ1_BOVIN Synaptojanin-1 OS=Bos taurus (Bov... | 176 | 3e-18 | 93.6 | 30 | 49 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 19 | Q9WVR3 | 1257 | SHIP2_RAT Phosphatidylinositol 3,4,5-trisphos... | 109 | 4 | 34.7 | 28 | 41 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0032957; P:inositol trisphosphate metabolic process; IDA:RGD.::GO:0008156; P:negative regulation of DNA replication; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IMP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD. | 20 | Q6P549 | 1257 | SHIP2_MOUSE Phosphatidylinositol 3,4,5-trisph... | 109 | 4.3 | 34.7 | 28 | 41 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI. | 21 | Q8K337 | 993 | I5P2_MOUSE Type II inositol 1,4,5-trisphospha... | 19 | 0.38 | 37.7 | 68 | 84 | GO:0005829; C:cytosol; IDA:MGI.::GO:0016021; C:integral to membrane; IDA:MGI. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0070613; P:regulation of protein processing; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 22 | Q92835 | 1189 | SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisph... | 37 | 6.1 | 33.9 | 43 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 23 | Q01968 | 901 | OCRL_HUMAN Inositol polyphosphate 5-phosphata... | 75 | 0.012 | 42.7 | 37 | 51 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc. | | | | | | | | | | GO:0004437; F:inositol or phosphatidylinositol phosphatase activity; TAS:ProtInc.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 24 | Q15735 | 1006 | PI5PA_HUMAN Phosphatidylinositol 4,5-bisphosp... | 19 | 1.7 | 35.8 | 68 | 84 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 25 | Q9JMC1 | 1001 | PI5PA_RAT Phosphatidylinositol 4,5-bisphospha... | 19 | 1.8 | 35.8 | 68 | 84 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031115; P:negative regulation of microtubule polymerization; IMP:RGD.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 26 | P59644 | 1003 | PI5PA_MOUSE Phosphatidylinositol 4,5-bisphosp... | 19 | 1.8 | 35.8 | 68 | 84 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:EC.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010977; P:negative regulation of neuron projection development; IMP:MGI.::GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 27 | P97573 | 1190 | SHIP1_RAT Phosphatidylinositol 3,4,5-trisphos... | 106 | 4 | 34.7 | 25 | 43 | GO:0005884; C:actin filament; IDA:RGD.::GO:0030863; C:cortical cytoskeleton; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0030487; F:inositol-4,5-bisphosphate 5-phosphatase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 28 | Q9SYK4 | 1136 | IP5PD_ARATH Type I inositol 1,4,5-trisphospha... | 37 | 0.073 | 40.4 | 43 | 65 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010252; P:auxin homeostasis; IMP:TAIR.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009637; P:response to blue light; IEP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR. | 29 | Q9ES52 | 1191 | SHIP1_MOUSE Phosphatidylinositol 3,4,5-trisph... | 37 | 5.6 | 34.3 | 43 | 54 | GO:0005622; C:intracellular; IMP:GOC.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:MGI.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0051425; F:PTB domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0016064; P:immunoglobulin mediated immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0050869; P:negative regulation of B cell activation; IMP:MGI.::GO:0030889; P:negative regulation of B cell proliferation; IMP:MGI.::GO:0045779; P:negative regulation of bone resorption; IMP:MGI.::GO:0050777; P:negative regulation of immune response; IMP:MGI.::GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0045656; P:negative regulation of monocyte differentiation; IMP:MGI.::GO:0045659; P:negative regulation of neutrophil differentiation; IMP:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IMP:MGI.::GO:0009968; P:negative regulation of signal transduction; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IMP:MGI.::GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:MGI. | 30 | P50942 | 1183 | INP52_YEAST Polyphosphatidylinositol phosphat... | 178 | 0.00000000000001 | 82 | 33 | 44 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 31 | O14306 | 1191 | YE8A_SCHPO Probable inositol polyphosphate 5-... | 64 | 0.53 | 37.4 | 33 | 58 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; ISS:PomBase. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; ISS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. |
