| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9VE01 | 536 | C12A5_DROME Probable cytochrome P450 12a5, mi... | 237 | 0.000000001 | 63.9 | 26 | 49 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 32 | Q08477 | 520 | CP4F3_HUMAN Leukotriene-B(4) omega-hydroxylas... | 243 | 0.000000002 | 63.9 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 33 | Q9EP75 | 524 | CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase ... | 273 | 0.000000002 | 63.9 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | | 34 | P78329 | 520 | CP4F2_HUMAN Leukotriene-B(4) omega-hydroxylas... | 243 | 0.000000002 | 63.9 | 27 | 42 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; IMP:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.::GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 35 | Q9V4T5 | 531 | CP4E1_DROME Probable cytochrome P450 4e1 OS=D... | 191 | 0.000000002 | 63.9 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 36 | P05180 | 491 | CP2H1_CHICK Cytochrome P450 2H1 OS=Gallus gal... | 275 | 0.000000002 | 63.5 | 25 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 37 | Q64406 | 503 | CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por... | 188 | 0.000000002 | 63.5 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 38 | P08682 | 493 | CP2E1_RABIT Cytochrome P450 2E1 OS=Oryctolagu... | 283 | 0.000000002 | 63.5 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 39 | P05181 | 493 | CP2E1_HUMAN Cytochrome P450 2E1 OS=Homo sapie... | 252 | 0.000000002 | 63.5 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 40 | P10614 | 530 | CP51_YEAST Lanosterol 14-alpha demethylase OS... | 227 | 0.000000002 | 63.2 | 24 | 45 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008398; F:sterol 14-demethylase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 41 | Q9STK7 | 489 | C71AQ_ARATH Cytochrome P450 71A26 OS=Arabidop... | 183 | 0.000000003 | 62.8 | 25 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 42 | Q9SAB6 | 497 | C71AI_ARATH Cytochrome P450 71A18 OS=Arabidop... | 244 | 0.000000003 | 62.8 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 43 | Q69FB6 | 503 | CP19A_LAGAC Cytochrome P450 19A1 OS=Lagenorhy... | 305 | 0.000000003 | 62.8 | 26 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 44 | O04164 | 511 | C71A6_NEPRA Cytochrome P450 71A6 OS=Nepeta ra... | 213 | 0.000000004 | 62.4 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 45 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 176 | 0.000000005 | 62.4 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 46 | O09158 | 503 | CP3AP_MOUSE Cytochrome P450 3A25 OS=Mus muscu... | 176 | 0.000000005 | 62.4 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 47 | Q4G0S4 | 372 | C27C1_HUMAN Cytochrome P450 27C1 OS=Homo sapi... | 189 | 0.000000005 | 61.6 | 24 | 50 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 48 | Q92112 | 509 | CP19A_TAEGU Cytochrome P450 19A1 OS=Taeniopyg... | 310 | 0.000000005 | 62 | 26 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 49 | P0A512 | 451 | CP51_MYCTU Lanosterol 14-alpha demethylase OS... | 261 | 0.000000005 | 62 | 25 | 44 | GO:0005829; C:cytosol; IDA:MTBBASE. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:MTBBASE.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0008398; F:sterol 14-demethylase activity; IDA:MTBBASE. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 50 | P0A513 | 451 | CP51_MYCBO Lanosterol 14-alpha demethylase OS... | 261 | 0.000000005 | 62 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 51 | P33274 | 524 | CP4F1_RAT Cytochrome P450 4F1 OS=Rattus norve... | 269 | 0.000000005 | 62 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0050544; F:arachidonic acid binding; IDA:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:RGD. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 52 | P24463 | 503 | CP3AC_CANFA Cytochrome P450 3A12 OS=Canis fam... | 186 | 0.000000007 | 61.6 | 24 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 53 | Q1ZXF5 | 501 | C5084_DICDI Probable cytochrome P450 508A4 OS... | 222 | 0.000000007 | 61.6 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 54 | P46194 | 503 | CP19A_BOVIN Cytochrome P450 19A1 OS=Bos tauru... | 305 | 0.000000008 | 61.6 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 55 | P33266 | 449 | CP2E1_MACFA Cytochrome P450 2E1 OS=Macaca fas... | 281 | 0.000000009 | 61.2 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 56 | Q940V4 | 465 | C85A2_ARATH Cytochrome P450 85A2 OS=Arabidops... | 298 | 0.00000001 | 61.2 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:TAIR.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IDA:TAIR. | 57 | P48421 | 502 | C83A1_ARATH Cytochrome P450 83A1 OS=Arabidops... | 235 | 0.00000001 | 61.2 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IDA:TAIR. | | | | | | | | | | GO:0019761; P:glucosinolate biosynthetic process; IDA:TAIR. | 58 | P79430 | 503 | CP192_PIG Cytochrome P450 19 type II OS=Sus s... | 303 | 0.00000001 | 61.2 | 25 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 59 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 176 | 0.00000001 | 61.2 | 25 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 60 | Q50LE0 | 467 | C85A3_SOLLC Cytochrome P450 85A3 OS=Solanum l... | 234 | 0.00000001 | 60.8 | 24 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 61 | Q9HCS2 | 524 | CP4FC_HUMAN Cytochrome P450 4F12 OS=Homo sapi... | 208 | 0.00000001 | 60.8 | 26 | 42 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; ISS:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; ISS:UniProtKB.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; ISS:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; ISS:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; ISS:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; ISS:UniProtKB.::GO:0003095; P:pressure natriuresis; ISS:UniProtKB.::GO:0003091; P:renal water homeostasis; ISS:UniProtKB.::GO:0055078; P:sodium ion homeostasis; ISS:UniProtKB.::GO:0042360; P:vitamin E metabolic process; ISS:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; ISS:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. |
