| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 211 | 0.0000006 | 55.8 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 122 | P20816 | 504 | CP4A2_RAT Cytochrome P450 4A2 OS=Rattus norve... | 223 | 0.0000007 | 55.5 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IMP:RGD.::GO:0008405; F:arachidonic acid 11,12-epoxygenase activity; TAS:RGD.::GO:0050544; F:arachidonic acid binding; IDA:RGD.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IMP:RGD.::GO:0046456; P:icosanoid biosynthetic process; IMP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0043651; P:linoleic acid metabolic process; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD. | 123 | P51538 | 503 | CP3A9_RAT Cytochrome P450 3A9 OS=Rattus norve... | 176 | 0.0000007 | 55.5 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; TAS:RGD. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 124 | O54750 | 501 | CP2J6_MOUSE Cytochrome P450 2J6 OS=Mus muscul... | 275 | 0.0000007 | 55.5 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 125 | Q98T91 | 502 | C340_ORYLA Cytochrome P450 3A40 OS=Oryzias la... | 177 | 0.0000008 | 55.1 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 126 | Q12645 | 515 | PID9_FUSSO Pisatin demethylase OS=Fusarium so... | 181 | 0.0000008 | 55.1 | 22 | 41 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 127 | Q9V4U9 | 493 | C6A13_DROME Probable cytochrome P450 6a13 OS=... | 254 | 0.0000009 | 55.1 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 128 | P33268 | 503 | CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas... | 280 | 0.0000009 | 55.1 | 21 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 129 | P33270 | 506 | CP6A2_DROME Cytochrome P450 6a2 OS=Drosophila... | 173 | 0.000001 | 55.1 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0031000; P:response to caffeine; IDA:FlyBase. | 130 | P51589 | 502 | CP2J2_HUMAN Cytochrome P450 2J2 OS=Homo sapie... | 258 | 0.000001 | 54.7 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0008405; F:arachidonic acid 11,12-epoxygenase activity; IDA:BHF-UCL.::GO:0008404; F:arachidonic acid 14,15-epoxygenase activity; IDA:BHF-UCL.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0071614; F:linoleic acid epoxygenase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:BHF-UCL.::GO:0043651; P:linoleic acid metabolic process; IDA:BHF-UCL.::GO:0008016; P:regulation of heart contraction; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 131 | Q8SPK0 | 504 | CP4AP_PIG Cytochrome P450 4A25 OS=Sus scrofa ... | 243 | 0.000001 | 54.7 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 132 | O49342 | 497 | C71AD_ARATH Indoleacetaldoxime dehydratase OS... | 205 | 0.000001 | 54.7 | 26 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0047720; F:indoleacetaldoxime dehydratase activity; IDA:TAIR.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0010120; P:camalexin biosynthetic process; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0050832; P:defense response to fungus; IMP:TAIR. | 133 | Q29605 | 503 | CP19A_RABIT Cytochrome P450 19A1 OS=Oryctolag... | 301 | 0.000001 | 54.7 | 23 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro. | | | | | | | | | | | 134 | Q29496 | 503 | CP3AO_SHEEP Cytochrome P450 3A24 OS=Ovis arie... | 176 | 0.000001 | 54.7 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 135 | Q8SPK1 | 504 | CP4AO_PIG Cytochrome P450 4A24 OS=Sus scrofa ... | 272 | 0.000001 | 54.7 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 136 | O46491 | 501 | CP7A1_PIG Cholesterol 7-alpha-monooxygenase O... | 135 | 0.000001 | 54.7 | 34 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; ISS:UniProtKB. | 137 | Q9V4I1 | 505 | CP9B2_DROME Cytochrome P450 9b2 OS=Drosophila... | 213 | 0.000001 | 54.3 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 138 | Q9GJX5 | 504 | CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro... | 250 | 0.000001 | 54.3 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC. | | | | | | | | | | | 139 | P11707 | 501 | CP3A6_RABIT Cytochrome P450 3A6 OS=Oryctolagu... | 181 | 0.000002 | 54.3 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 140 | P93147 | 499 | C81E1_GLYEC Isoflavone 2'-hydroxylase OS=Glyc... | 267 | 0.000002 | 54.3 | 22 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033773; F:isoflavone 2'-hydroxylase activity; IEA:EC. | | | | | | | | | | | 141 | P79152 | 218 | CP3AJ_CAPAE Cytochrome P450 3A19 OS=Capra aeg... | 174 | 0.000002 | 52.4 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 142 | O46051 | 507 | C4D14_DROME Probable cytochrome P450 4d14 OS=... | 187 | 0.000002 | 54.3 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 143 | P38364 | 506 | PID6_FUSSO Pisatin demethylase OS=Fusarium so... | 181 | 0.000002 | 54.3 | 23 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 144 | Q9GQM9 | 503 | CP6L1_BLAGE Cytochrome P450 6l1 OS=Blattella ... | 209 | 0.000002 | 53.9 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 145 | P93596 | 453 | CP51_WHEAT Obtusifoliol 14-alpha demethylase ... | 195 | 0.000002 | 53.9 | 27 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 146 | Q02318 | 531 | CP27A_HUMAN Sterol 26-hydroxylase, mitochondr... | 208 | 0.000002 | 54.3 | 23 | 46 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 147 | P17178 | 533 | CP27A_RAT Sterol 26-hydroxylase, mitochondria... | 210 | 0.000002 | 53.9 | 22 | 46 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0031073; F:cholesterol 26-hydroxylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:RGD.::GO:0006706; P:steroid catabolic process; TAS:RGD. | 148 | Q6XQ14 | 511 | C71E7_MANES 2-methylbutanal oxime monooxygena... | 261 | 0.000002 | 53.9 | 21 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC. | | | | | | | | | | | 149 | Q9DBG1 | 533 | CP27A_MOUSE Sterol 26-hydroxylase, mitochondr... | 210 | 0.000002 | 53.9 | 21 | 45 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 150 | Q8GSQ1 | 469 | C85A1_ORYSJ Cytochrome P450 85A1 OS=Oryza sat... | 239 | 0.000002 | 53.9 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:Gramene.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IEA:UniProtKB-KW.::GO:0010268; P:brassinosteroid homeostasis; IMP:Gramene.::GO:0022900; P:electron transport chain; ISS:Gramene.::GO:0001578; P:microtubule bundle formation; IMP:Gramene.::GO:0009647; P:skotomorphogenesis; IMP:Gramene. | 151 | O75881 | 506 | CP7B1_HUMAN 25-hydroxycholesterol 7-alpha-hyd... | 188 | 0.000002 | 53.9 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. |
