rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8U3Y2 | 336 | GYAR_PYRFU Glyoxylate reductase OS=Pyrococcus... | 292 | 5e-42 | 154 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 32 | A1RYE4 | 339 | GYAR_THEPD Glyoxylate reductase OS=Thermofilu... | 285 | 6e-42 | 154 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 33 | Q9C4M5 | 331 | GYAR_THELI Glyoxylate reductase OS=Thermococc... | 292 | 7e-42 | 154 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 34 | Q9YAW4 | 335 | GYAR_AERPE Glyoxylate reductase OS=100138 / K... | 304 | 4e-39 | 146 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 35 | O27051 | 525 | SERA_METTH D-3-phosphoglycerate dehydrogenase... | 281 | 2e-38 | 147 | 34 | 52 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 36 | B6YWH0 | 334 | GYAR_THEON Glyoxylate reductase OS=Thermococc... | 292 | 4e-38 | 144 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 37 | O46036 | 476 | CTBP_DROME C-terminal-binding protein OS=Dros... | 261 | 1e-36 | 142 | 36 | 53 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IDA:FlyBase.::GO:0003714; F:transcription corepressor activity; IDA:FlyBase. | | | | | | | | | | GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:FlyBase. | 38 | O29445 | 527 | SERA_ARCFU D-3-phosphoglycerate dehydrogenase... | 277 | 2e-36 | 142 | 32 | 51 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 39 | Q9W758 | 437 | CTBP2_XENLA C-terminal-binding protein 2 OS=X... | 249 | 2e-36 | 140 | 35 | 55 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 40 | Q5JEZ2 | 333 | GYAR_PYRKO Glyoxylate reductase OS=(Thermococ... | 304 | 9e-36 | 137 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 41 | O04130 | 624 | SERA_ARATH D-3-phosphoglycerate dehydrogenase... | 266 | 2e-35 | 139 | 35 | 52 | GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 42 | P0A544 | 528 | SERA_MYCTU D-3-phosphoglycerate dehydrogenase... | 280 | 3e-35 | 138 | 35 | 53 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0006564; P:L-serine biosynthetic process; IDA:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE. | 43 | P0A545 | 528 | SERA_MYCBO D-3-phosphoglycerate dehydrogenase... | 280 | 3e-35 | 138 | 35 | 53 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 44 | P56546 | 445 | CTBP2_MOUSE C-terminal-binding protein 2 OS=M... | 273 | 3e-35 | 137 | 33 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 45 | Q9EQH5 | 445 | CTBP2_RAT C-terminal-binding protein 2 OS=Rat... | 273 | 3e-35 | 137 | 33 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 46 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 273 | 5e-35 | 137 | 33 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 47 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 273 | 2e-34 | 135 | 33 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 48 | A5A6P1 | 533 | SERA_PANTR D-3-phosphoglycerate dehydrogenase... | 208 | 2e-34 | 136 | 36 | 58 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 49 | O43175 | 533 | SERA_HUMAN D-3-phosphoglycerate dehydrogenase... | 208 | 2e-34 | 136 | 36 | 58 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:Reactome. | | | | | | | | | | GO:0007420; P:brain development; TAS:ProtInc.::GO:0006564; P:L-serine biosynthetic process; TAS:Reactome. | 50 | O08651 | 533 | SERA_RAT D-3-phosphoglycerate dehydrogenase O... | 209 | 2e-34 | 135 | 35 | 58 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 51 | Q61753 | 533 | SERA_MOUSE D-3-phosphoglycerate dehydrogenase... | 208 | 3e-34 | 135 | 36 | 57 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:MGI. | | | | | | | | | | GO:0022402; P:cell cycle process; IMP:MGI.::GO:0009448; P:gamma-aminobutyric acid metabolic process; IMP:MGI.::GO:0021782; P:glial cell development; IMP:MGI.::GO:0006541; P:glutamine metabolic process; IMP:MGI.::GO:0006544; P:glycine metabolic process; IMP:MGI.::GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.::GO:0021915; P:neural tube development; IMP:MGI.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI.::GO:0019530; P:taurine metabolic process; IMP:MGI.::GO:0006566; P:threonine metabolic process; IMP:MGI. | 52 | Q5R7M2 | 533 | SERA_PONAB D-3-phosphoglycerate dehydrogenase... | 209 | 3e-34 | 135 | 36 | 58 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 53 | Q60HD7 | 533 | SERA_MACFA D-3-phosphoglycerate dehydrogenase... | 208 | 4e-34 | 135 | 35 | 58 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 54 | O33116 | 528 | SERA_MYCLE D-3-phosphoglycerate dehydrogenase... | 281 | 9e-34 | 134 | 35 | 53 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 55 | P35136 | 525 | SERA_BACSU D-3-phosphoglycerate dehydrogenase... | 299 | 1e-33 | 133 | 32 | 51 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 56 | P53839 | 350 | GOR1_YEAST Glyoxylate reductase 1 OS=Saccharo... | 254 | 1e-33 | 131 | 33 | 53 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IMP:SGD.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009436; P:glyoxylate catabolic process; IMP:SGD. | 57 | Q5EAD2 | 533 | SERA_BOVIN D-3-phosphoglycerate dehydrogenase... | 208 | 1e-33 | 133 | 35 | 57 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 58 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 249 | 2e-33 | 132 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 59 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 249 | 3e-33 | 132 | 33 | 53 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 60 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 249 | 3e-33 | 132 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 61 | Q663W4 | 326 | GHRB_YERPS Glyoxylate/hydroxypyruvate reducta... | 259 | 7e-33 | 129 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | |