| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q17392 | 840 | CUL4_CAEEL Cullin-4 OS=Caenorhabditis elegans... | 478 | 2e-49 | 184 | 29 | 50 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 32 | Q93034 | 780 | CUL5_HUMAN Cullin-5 OS=Homo sapiens (Human). ... | 392 | 1e-47 | 179 | 31 | 54 | GO:0031466; C:Cul5-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005262; F:calcium channel activity; TAS:ProtInc.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016032; P:viral reproduction; TAS:Reactome. | 33 | Q9JJ31 | 780 | CUL5_RAT Cullin-5 OS=Rattus norvegicus (Rat).... | 392 | 2e-47 | 178 | 31 | 54 | GO:0031466; C:Cul5-RING ubiquitin ligase complex; TAS:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:RGD.::GO:0005000; F:vasopressin receptor activity; TAS:RGD. | | | | | | | | | | GO:0051480; P:cytosolic calcium ion homeostasis; IMP:RGD.::GO:0000209; P:protein polyubiquitination; TAS:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 34 | Q5RB36 | 780 | CUL5_PONAB Cullin-5 OS=Pongo abelii (Sumatran... | 392 | 2e-47 | 178 | 31 | 54 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 35 | Q9D5V5 | 780 | CUL5_MOUSE Cullin-5 OS=Mus musculus (Mouse). ... | 392 | 4e-47 | 177 | 31 | 54 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 36 | Q29425 | 780 | CUL5_RABIT Cullin-5 OS=Oryctolagus cuniculus ... | 392 | 7e-46 | 174 | 31 | 54 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 37 | Q24311 | 774 | CUL1_DROME Cullin homolog 1 OS=Drosophila mel... | 444 | 4e-44 | 169 | 28 | 48 | GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 38 | Q23639 | 765 | CUL5_CAEEL Cullin-5 OS=Caenorhabditis elegans... | 385 | 9e-40 | 156 | 30 | 51 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0006468; P:protein phosphorylation; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 39 | Q17389 | 780 | CUL1_CAEEL Cullin-1 OS=Caenorhabditis elegans... | 470 | 5e-38 | 151 | 27 | 48 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:WormBase.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008361; P:regulation of cell size; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 40 | Q54XF7 | 750 | CUL5_DICDI Cullin-5 OS=Dictyostelium discoide... | 470 | 4e-36 | 145 | 27 | 47 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 41 | Q17390 | 850 | CUL2_CAEEL Cullin-2 OS=Caenorhabditis elegans... | 384 | 4e-36 | 146 | 28 | 47 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0008595; P:anterior/posterior axis specification, embryo; IMP:WormBase.::GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0042078; P:germ-line stem cell division; IMP:WormBase.::GO:0007138; P:meiotic anaphase II; IMP:WormBase.::GO:0051232; P:meiotic spindle elongation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051759; P:sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation; IMP:WormBase. | 42 | Q12018 | 815 | CDC53_YEAST Cell division control protein 53 ... | 385 | 3e-35 | 143 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0003688; F:DNA replication origin binding; IPI:SGD.::GO:0030674; F:protein binding, bridging; IMP:SGD.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD. | 43 | Q21346 | 729 | CUL6_CAEEL Cullin-6 OS=Caenorhabditis elegans... | 484 | 3e-33 | 137 | 25 | 44 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 44 | P53202 | 744 | CUL3_YEAST Cullin-3 OS=Saccharomyces cerevisi... | 384 | 3e-30 | 128 | 26 | 47 | GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD. | 45 | Q8BZQ7 | 837 | ANC2_MOUSE Anaphase-promoting complex subunit... | 203 | 0.000000000003 | 72.4 | 29 | 49 | GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 46 | Q9UJX6 | 822 | ANC2_HUMAN Anaphase-promoting complex subunit... | 203 | 0.00000000002 | 70.1 | 28 | 48 | GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc. | 47 | Q80TT8 | 1865 | CUL9_MOUSE Cullin-9 OS=Mus musculus (Mouse). ... | 208 | 0.0008 | 45.8 | 25 | 42 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 48 | Q8H1U5 | 865 | APC2_ARATH Anaphase-promoting complex subunit... | 103 | 0.01 | 42 | 25 | 50 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:UniProtKB. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009561; P:megagametogenesis; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 49 | Q874R3 | 681 | APC2_SCHPO Anaphase-promoting complex subunit... | 141 | 0.012 | 41.6 | 25 | 48 | GO:0005680; C:anaphase-promoting complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase. | 50 | Q5UQT0 | 281 | YR337_MIMIV Uncharacterized cullin-like prote... | 121 | 0.015 | 40.8 | 22 | 46 | GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 51 | P47050 | 842 | CUL8_YEAST Regulator of Ty1 transposition pro... | 132 | 0.028 | 40.8 | 27 | 46 | GO:0035361; C:Cul8-RING ubiquitin ligase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD. | | | | | | | | | | GO:0010526; P:negative regulation of transposition, RNA-mediated; IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0031297; P:replication fork processing; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:SGD. | 52 | Q551S9 | 907 | APC2_DICDI Anaphase-promoting complex subunit... | 83 | 3 | 34.3 | 22 | 46 | GO:0005680; C:anaphase-promoting complex; ISS:dictyBase.::GO:0005829; C:cytosol; ISS:dictyBase. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:dictyBase. | 53 | Q9ZDC7 | 281 | Y404_RICPR Putative glutamine amidotransferas... | 65 | 3.9 | 33.1 | 28 | 49 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. |
