Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
216986
Length:
838
Number of sequences:
10438
Description:
estExt_Genewise1.C_21530
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q8SSY6    1887   SPKUL_DICDI Bifunctional serine/threonine-pro...800.0009     47     35     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
92O95071    2799   UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 O...2915e-20     100     27     44GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:BHF-UCL.::GO:0050847; P:progesterone receptor signaling pathway; IDA:HGNC.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IDA:HGNC.
93Q80TP3    2792   UBR5_MOUSE E3 ubiquitin-protein ligase UBR5 O...2915e-20     100     27     44GO:0005634; C:nucleus; ISS:HGNC.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050847; P:progesterone receptor signaling pathway; ISS:HGNC.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:HGNC.
94Q62671    2788   UBR5_RAT E3 ubiquitin-protein ligase UBR5 OS=...2916e-20     99.8     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
95Q3U487    861   HECD3_MOUSE E3 ubiquitin-protein ligase HECTD...3431e-19     97.8     27     45GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0019905; F:syntaxin binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
96Q5T447    861   HECD3_HUMAN E3 ubiquitin-protein ligase HECTD...3434e-19     96.3     27     45GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
97Q2EJA0    469   YAP1_RAT Yorkie homolog OS=Rattus norvegicus ...420.000004     53.9     55     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0071480; P:cellular response to gamma radiation; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98P46938    488   YAP1_MOUSE Yorkie homolog OS=Mus musculus (Mo...560.025     41.6     39     52GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IPI:MGI.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0071480; P:cellular response to gamma radiation; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.::GO:0030857; P:negative regulation of epithelial cell differentiation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:MGI.::GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.::GO:0046622; P:positive regulation of organ growth; IDA:MGI.::GO:0010837; P:regulation of keratinocyte proliferation; IMP:MGI.::GO:0072091; P:regulation of stem cell proliferation; IDA:MGI.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.
99P33202    1483   UFD4_YEAST Ubiquitin fusion degradation prote...2982e-17     90.9     25     44GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
100Q10435    1647   YDE1_SCHPO Probable ubiquitin fusion degradat...4638e-17     89.4     26     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
101P46937    504   YAP1_HUMAN Yorkie homolog OS=Homo sapiens (Hu...320.0002     48.9     59     78GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0071480; P:cellular response to gamma radiation; IDA:UniProtKB.::GO:0060242; P:contact inhibition; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
102A4IIJ3    1108   KIBRA_XENTR Protein KIBRA OS=Xenopus tropical...320.001     46.2     53     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103Q9ULT8    2610   HECD1_HUMAN E3 ubiquitin-protein ligase HECTD...1940.00000000000006     80.1     27     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
104Q45VV3    418   YORKI_DROME Protein yorkie OS=Drosophila mela...340.0004     47.4     50     74GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:FlyBase.
GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q8IX03    1113   KIBRA_HUMAN Protein KIBRA OS=Homo sapiens (Hu...320.007     43.9     50     66GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:Reactome.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0035330; P:regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106Q5SXA9    1104   KIBRA_MOUSE Protein KIBRA OS=Mus musculus (Mo...320.008     43.9     50     66GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
107Q69ZR2    2618   HECD1_MOUSE E3 ubiquitin-protein ligase HECTD...1970.000000000001     75.9     26     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0001843; P:neural tube closure; IMP:UniProtKB.
108Q6AWC2    1192   WWC2_HUMAN Protein WWC2 OS=Homo sapiens (Huma...310.004     44.7     55     68
109Q6NXJ0    1187   WWC2_MOUSE Protein WWC2 OS=Mus musculus (Mous...310.004     44.7     55     68
110Q91WL8    414   WWOX_MOUSE WW domain-containing oxidoreductas...393.1     35     38     59GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
111Q9NZC7    414   WWOX_HUMAN WW domain-containing oxidoreductas...393.4     34.7     38     59GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
112Q5F389    414   WWOX_CHICK WW domain-containing oxidoreductas...381.4     36.2     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
113Q5R9W5    414   WWOX_PONAB WW domain-containing oxidoreductas...396.3     33.9     38     59GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
114Q9Y4D8    3996   K0614_HUMAN Probable E3 ubiquitin-protein lig...1890.0000000006     67.4     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
115Q6DJR2    1171   WWC2_XENTR Protein WWC2 OS=Xenopus tropicalis...1320.0002     48.9     25     37
116Q6RHR9    1471   MAGI1_MOUSE Membrane-associated guanylate kin...340.27     38.5     50     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
117Q96QZ7    1491   MAGI1_HUMAN Membrane-associated guanylate kin...340.3     38.5     50     59GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0051393; F:alpha-actinin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006461; P:protein complex assembly; NAS:ProtInc.
118Q4L1J4    1255   MAGI1_RAT Membrane-associated guanylate kinas...340.16     39.3     50     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
119A1A5G4    1107   MAGI3_XENTR Membrane-associated guanylate kin...360.67     37.4     47     58GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
120O88382    1277   MAGI2_RAT Membrane-associated guanylate kinas...440.000001     56.2     55     64GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0036057; C:slit diaphragm; IDA:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
GO:0003094; P:glomerular filtration; IC:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0043113; P:receptor clustering; IDA:RGD.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
121Q9WVQ1    1275   MAGI2_MOUSE Membrane-associated guanylate kin...1150.081     40.4     30     40GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
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