| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q9WVQ1 | 1275 | MAGI2_MOUSE Membrane-associated guanylate kin... | 115 | 0.081 | 40.4 | 30 | 40 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB. | 122 | Q86UL8 | 1455 | MAGI2_HUMAN Membrane-associated guanylate kin... | 31 | 0.23 | 38.9 | 48 | 61 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB. | 123 | Q5F488 | 1128 | MAGI3_CHICK Membrane-associated guanylate kin... | 36 | 1.3 | 36.6 | 47 | 56 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 124 | Q9EQJ9 | 1476 | MAGI3_MOUSE Membrane-associated guanylate kin... | 51 | 0.5 | 37.7 | 37 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005109; F:frizzled binding; IPI:MGI. | | | | | | | | | | | 125 | Q9JK71 | 1470 | MAGI3_RAT Membrane-associated guanylate kinas... | 51 | 0.13 | 39.7 | 39 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 126 | Q803A8 | 412 | WWOX_DANRE WW domain-containing oxidoreductas... | 143 | 0.046 | 40.8 | 22 | 31 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 127 | B4K6I9 | 1264 | KIBRA_DROMO Protein kibra OS=Drosophila mojav... | 32 | 0.053 | 40.8 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 128 | Q5TCQ9 | 1506 | MAGI3_HUMAN Membrane-associated guanylate kin... | 42 | 0.04 | 41.6 | 43 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB. | 129 | B3LWS4 | 1271 | KIBRA_DROAN Protein kibra OS=Drosophila anana... | 32 | 0.053 | 40.8 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 130 | B4M5X4 | 1276 | KIBRA_DROVI Protein kibra OS=Drosophila viril... | 32 | 0.043 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 131 | B4PSQ2 | 1288 | KIBRA_DROYA Protein kibra OS=Drosophila yakub... | 32 | 0.05 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 132 | B4HEJ6 | 1295 | KIBRA_DROSE Protein kibra OS=Drosophila seche... | 32 | 0.049 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 133 | B3P3M8 | 1283 | KIBRA_DROER Protein kibra OS=Drosophila erect... | 32 | 0.05 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 134 | Q9VFG8 | 1288 | KIBRA_DROME Protein kibra OS=Drosophila melan... | 32 | 0.051 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0001745; P:compound eye morphogenesis; IGI:FlyBase.::GO:0035330; P:regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 135 | Q8VEB2 | 386 | SAV1_MOUSE Protein salvador homolog 1 OS=Mus ... | 31 | 0.04 | 40.8 | 55 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0001942; P:hair follicle development; IMP:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0060575; P:intestinal epithelial cell differentiation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IMP:MGI.::GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0060412; P:ventricular septum morphogenesis; IMP:MGI. | 136 | A4V8B4 | 387 | SAV1_RAT Protein salvador homolog 1 OS=Rattus... | 31 | 0.048 | 40.8 | 55 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 137 | B4NAD3 | 1288 | KIBRA_DROWI Protein kibra OS=Drosophila willi... | 32 | 0.048 | 41.2 | 47 | 63 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 138 | C6KTB7 | 10287 | ALTH1_PLAF7 Putative E3 ubiquitin-protein lig... | 275 | 0.000002 | 55.8 | 24 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro. | 139 | Q9H4B6 | 383 | SAV1_HUMAN Protein salvador homolog 1 OS=Homo... | 31 | 0.042 | 40.8 | 55 | 61 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 140 | Q62768 | 1735 | UN13A_RAT Protein unc-13 homolog A OS=Rattus ... | 138 | 0.000002 | 55.5 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0000149; F:SNARE binding; IDA:RGD. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0016082; P:synaptic vesicle priming; IDA:RGD. | 141 | Q4KUS2 | 1712 | UN13A_MOUSE Protein unc-13 homolog A OS=Mus m... | 138 | 0.000002 | 55.5 | 32 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019992; F:diacylglycerol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI. | 142 | Q9UPW8 | 1703 | UN13A_HUMAN Protein unc-13 homolog A OS=Homo ... | 138 | 0.000002 | 55.5 | 32 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 143 | Q6DN14 | 999 | MCTP1_HUMAN Multiple C2 and transmembrane dom... | 107 | 1.1 | 36.6 | 27 | 47 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 144 | O95817 | 575 | BAG3_HUMAN BAG family molecular chaperone reg... | 53 | 0.0002 | 48.5 | 47 | 64 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0051087; F:chaperone binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; NAS:UniProtKB. | 145 | O14795 | 1591 | UN13B_HUMAN Protein unc-13 homolog B OS=Homo ... | 139 | 0.00002 | 52.8 | 30 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007588; P:excretion; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 146 | Q6IQ23 | 1121 | PKHA7_HUMAN Pleckstrin homology domain-contai... | 30 | 5.5 | 34.3 | 43 | 60 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005915; C:zonula adherens; IDA:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.::GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB. | 147 | Q9Z1N9 | 1602 | UN13B_MOUSE Protein unc-13 homolog B OS=Mus m... | 139 | 0.00002 | 52.4 | 30 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001566; F:non-kinase phorbol ester receptor activity; TAS:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI. | 148 | Q9JLV1 | 577 | BAG3_MOUSE BAG family molecular chaperone reg... | 67 | 0.0002 | 48.5 | 42 | 58 | | | | | | | | | | | GO:0051087; F:chaperone binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI. | 149 | Q54T86 | 568 | DWWA_DICDI WW domain-containing protein A OS=... | 48 | 0.36 | 38.1 | 38 | 58 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:dictyBase.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 150 | O14065 | 1429 | YC31_SCHPO Uncharacterized protein C962.01 OS... | 98 | 0.00004 | 51.2 | 36 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008289; F:lipid binding; ISS:PomBase. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 151 | Q62769 | 1622 | UN13B_RAT Protein unc-13 homolog B OS=Rattus ... | 139 | 0.00005 | 50.8 | 29 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. |
