Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
216667
Length:
800
Number of sequences:
10438
Description:
estExt_Genewise1.C_21094
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P42892    770   ECE1_HUMAN Endothelin-converting enzyme 1 OS=...7577e-107     352     31     50GO:0005769; C:early endosome; IDA:BHF-UCL.::GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IDA:BHF-UCL.::GO:0031302; C:intrinsic to endosome membrane; TAS:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0033093; C:Weibel-Palade body; IDA:BHF-UCL.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:BHF-UCL.::GO:0017046; F:peptide hormone binding; IC:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
GO:0010815; P:bradykinin catabolic process; IDA:BHF-UCL.::GO:0010816; P:calcitonin catabolic process; IDA:BHF-UCL.::GO:0043583; P:ear development; IMP:BHF-UCL.::GO:0042733; P:embryonic digit morphogenesis; IMP:BHF-UCL.::GO:0034959; P:endothelin maturation; IDA:BHF-UCL.::GO:0007507; P:heart development; IMP:BHF-UCL.::GO:0001921; P:positive regulation of receptor recycling; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IC:BHF-UCL.::GO:0019229; P:regulation of vasoconstriction; IC:BHF-UCL.::GO:0010814; P:substance P catabolic process; IDA:BHF-UCL.
2Q4PZA2    769   ECE1_MOUSE Endothelin-converting enzyme 1 OS=...7564e-105     347     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0060037; P:pharyngeal system development; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3P42891    754   ECE1_BOVIN Endothelin-converting enzyme 1 OS=...7536e-104     343     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; ISS:AgBase.
4P42893    762   ECE1_RAT Endothelin-converting enzyme 1 OS=Ra...7571e-103     343     30     49GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:RGD.::GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IMP:RGD.::GO:0006508; P:proteolysis; IDA:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.
5P97739    754   ECE1_CAVPO Endothelin-converting enzyme 1 OS=...7561e-100     334     29     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6Q495T6    779   MMEL1_HUMAN Membrane metallo-endopeptidase-li...7752e-99     332     29     48GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7Q9JLI3    765   MMEL1_MOUSE Membrane metallo-endopeptidase-li...7588e-97     324     29     49GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005615; C:extracellular space; TAS:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8O60344    883   ECE2_HUMAN Endothelin-converting enzyme 2 OS=...7666e-95     322     30     48GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; TAS:UniProtKB.::GO:0016486; P:peptide hormone processing; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9P0C1T0    774   MMEL1_RAT Membrane metallo-endopeptidase-like...7613e-92     312     28     48GO:0005615; C:extracellular space; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0004222; F:metalloendopeptidase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10P08473    750   NEP_HUMAN Neprilysin OS=Homo sapiens (Human)....7738e-91     308     29     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0005903; C:brush border; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0044306; C:neuron projection terminus; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.::GO:0042277; F:peptide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.::GO:0071492; P:cellular response to UV-A; IDA:UniProtKB.::GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.::GO:0046449; P:creatinine metabolic process; IMP:UniProtKB.::GO:0001822; P:kidney development; IEP:UniProtKB.::GO:0006518; P:peptide metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IDA:UniProtKB.::GO:0090399; P:replicative senescence; IEP:UniProtKB.::GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
11Q5RE69    750   NEP_PONAB Neprilysin OS=Pongo abelii (Sumatra...7737e-90     305     28     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0005903; C:brush border; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044306; C:neuron projection terminus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042277; F:peptide binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.::GO:0071492; P:cellular response to UV-A; ISS:UniProtKB.::GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.::GO:0046449; P:creatinine metabolic process; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0006518; P:peptide metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0090399; P:replicative senescence; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
12Q61391    750   NEP_MOUSE Neprilysin OS=Mus musculus (Mouse)....7653e-89     303     28     46GO:0030424; C:axon; IDA:MGI.::GO:0005903; C:brush border; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044306; C:neuron projection terminus; IDA:MGI.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; IDA:MGI.
GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042277; F:peptide binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IDA:MGI.::GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.::GO:0071492; P:cellular response to UV-A; ISS:UniProtKB.::GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.::GO:0046449; P:creatinine metabolic process; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0006518; P:peptide metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0090399; P:replicative senescence; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB.
13P07861    750   NEP_RAT Neprilysin OS=Rattus norvegicus (Rat)...7655e-88     300     28     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0005903; C:brush border; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044306; C:neuron projection terminus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001950; C:plasma membrane enriched fraction; IDA:RGD.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.::GO:0071492; P:cellular response to UV-A; ISS:UniProtKB.::GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.::GO:0046449; P:creatinine metabolic process; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0006518; P:peptide metabolic process; IMP:RGD.::GO:0006508; P:proteolysis; IDA:RGD.::GO:0090399; P:replicative senescence; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
14P08049    750   NEP_RABIT Neprilysin OS=Oryctolagus cuniculus...7712e-86     296     27     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0005903; C:brush border; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044306; C:neuron projection terminus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042277; F:peptide binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.::GO:0071492; P:cellular response to UV-A; ISS:UniProtKB.::GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.::GO:0046449; P:creatinine metabolic process; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0006518; P:peptide metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0090399; P:replicative senescence; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
15O16796    848   NEPL2_CAEEL Neprilysin-2 OS=Caenorhabditis el...7734e-86     297     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16P70669    749   PHEX_MOUSE Metalloendopeptidase homolog PEX O...7647e-82     283     28     46GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17O95672    775   ECEL1_HUMAN Endothelin-converting enzyme-like...7463e-81     282     27     45GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
18P78562    749   PHEX_HUMAN Phosphate-regulating neutral endop...7633e-81     281     28     46GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006464; P:protein modification process; TAS:ProtInc.::GO:0006508; P:proteolysis; IDA:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.
19Q9JMI0    775   ECEL1_MOUSE Endothelin-converting enzyme-like...7611e-80     281     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:MGI.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20Q9JHL3    775   ECEL1_RAT Endothelin-converting enzyme-like 1...7702e-79     277     26     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IDA:GOC.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; TAS:RGD.
GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007218; P:neuropeptide signaling pathway; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21Q80Z60    881   ECE2_MOUSE Endothelin-converting enzyme 2 OS=...1403e-16     87     33     54GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.::GO:0016486; P:peptide hormone processing; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
22Q10711    883   ECE2_BOVIN Endothelin-converting enzyme 2 OS=...1210.0000000000003     77     32     54GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.::GO:0009790; P:embryo development; TAS:UniProtKB.::GO:0016486; P:peptide hormone processing; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:UniProtKB.::GO:0042310; P:vasoconstriction; TAS:UniProtKB.
23Q18673    754   NEPL1_CAEEL Neprilysin-1 OS=Caenorhabditis el...7484e-74     262     26     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.
24Q22523    769   YCYL_CAEEL Putative zinc metalloproteinase T1...1940.002     45.4     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25Q07744    627   PEPO_LACLA Neutral endopeptidase OS=lactis). ...5202e-40     161     24     44
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
26P23276    732   KELL_HUMAN Kell blood group glycoprotein OS=H...7681e-39     160     23     42GO:0016021; C:integral to membrane; TAS:HGNC.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:HGNC.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042310; P:vasoconstriction; TAS:HGNC.
27Q02VB0    627   PEPO_LACLS Neutral endopeptidase OS=Lactococc...5201e-39     159     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
28P0C2B4    627   PEPO_LACLC Neutral endopeptidase OS=Lactococc...5201e-39     159     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29O52071    647   PEPO_LACHE Neutral endopeptidase OS=Lactobaci...4627e-34     142     24     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30Q9EQF2    713   KELL_MOUSE Kell blood group glycoprotein homo...1160.039     41.2     26     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:HGNC.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31P42359    564   YSC6_STRGC Putative zinc metalloproteinase in...3544e-32     135     25     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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