| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9US48 | 581 | GAA1_SCHPO GPI transamidase component gaa1 OS... | 417 | 3e-48 | 182 | 29 | 48 | GO:0042765; C:GPI-anchor transamidase complex; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0016255; P:attachment of GPI anchor to protein; ISS:PomBase. | 2 | P39012 | 614 | GAA1_YEAST GPI transamidase component GAA1 OS... | 552 | 4e-48 | 182 | 28 | 47 | GO:0042765; C:GPI-anchor transamidase complex; IPI:SGD. | | | | | | | | | | GO:0003923; F:GPI-anchor transamidase activity; IMP:SGD. | | | | | | | | | | GO:0016255; P:attachment of GPI anchor to protein; IMP:SGD. | 3 | Q9WTK3 | 621 | GPAA1_MOUSE Glycosylphosphatidylinositol anch... | 600 | 4e-42 | 164 | 28 | 44 | GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro. | | | | | | | | | | GO:0003923; F:GPI-anchor transamidase activity; TAS:MGI. | | | | | | | | | | GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW. | 4 | O43292 | 621 | GPAA1_HUMAN Glycosylphosphatidylinositol anch... | 594 | 8e-42 | 163 | 27 | 45 | GO:0042765; C:GPI-anchor transamidase complex; TAS:UniProtKB. | | | | | | | | | | GO:0015631; F:tubulin binding; NAS:UniProtKB. | | | | | | | | | | GO:0016255; P:attachment of GPI anchor to protein; NAS:UniProtKB.::GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.::GO:0006461; P:protein complex assembly; NAS:UniProtKB.::GO:0006621; P:protein retention in ER lumen; NAS:UniProtKB. | 5 | O76024 | 890 | WFS1_HUMAN Wolframin OS=Homo sapiens (Human).... | 52 | 3.3 | 34.7 | 35 | 56 | GO:0030425; C:dendrite; ISS:BHF-UCL.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; ISS:BHF-UCL.::GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0005215; F:transporter activity; ISS:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IDA:BHF-UCL.::GO:0006983; P:ER overload response; TAS:BHF-UCL.::GO:0030433; P:ER-associated protein catabolic process; ISS:BHF-UCL.::GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0070845; P:polyubiquitinated misfolded protein transport; ISS:BHF-UCL.::GO:0051928; P:positive regulation of calcium ion transport; IDA:BHF-UCL.::GO:0045927; P:positive regulation of growth; ISS:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; ISS:BHF-UCL.::GO:0022417; P:protein maturation by protein folding; IC:BHF-UCL.::GO:0050821; P:protein stabilization; ISS:BHF-UCL.::GO:0003091; P:renal water homeostasis; IMP:BHF-UCL.::GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.::GO:0007601; P:visual perception; IMP:BHF-UCL. | 6 | P56695 | 890 | WFS1_MOUSE Wolframin OS=Mus musculus (Mouse).... | 49 | 3.8 | 34.3 | 37 | 57 | GO:0030425; C:dendrite; ISS:BHF-UCL.::GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IDA:BHF-UCL.::GO:0051117; F:ATPase binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; ISS:BHF-UCL.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:BHF-UCL.::GO:0030433; P:ER-associated protein catabolic process; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.::GO:0001822; P:kidney development; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; IMP:BHF-UCL.::GO:0070845; P:polyubiquitinated misfolded protein transport; IDA:BHF-UCL.::GO:0051928; P:positive regulation of calcium ion transport; ISS:BHF-UCL.::GO:0045927; P:positive regulation of growth; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IMP:BHF-UCL.::GO:0051726; P:regulation of cell cycle; NAS:BHF-UCL.::GO:0003091; P:renal water homeostasis; ISS:BHF-UCL.::GO:0007605; P:sensory perception of sound; ISS:BHF-UCL.::GO:0007601; P:visual perception; ISS:BHF-UCL. | 7 | O73864 | 354 | WNT11_DANRE Protein Wnt-11 OS=Danio rerio (Ze... | 90 | 7.3 | 33.1 | 29 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:ZFIN.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.::GO:0009798; P:axis specification; IBA:RefGenome.::GO:0016337; P:cell-cell adhesion; IMP:ZFIN.::GO:0007417; P:central nervous system development; IMP:ZFIN.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0060898; P:eye field cell fate commitment involved in camera-type eye formation; IMP:ZFIN.::GO:0001702; P:gastrulation with mouth forming second; IMP:ZFIN.::GO:0007507; P:heart development; IMP:ZFIN.::GO:0060031; P:mediolateral intercalation; IMP:ZFIN.::GO:0008078; P:mesodermal cell migration; IMP:ZFIN.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001839; P:neural plate morphogenesis; IMP:ZFIN.::GO:0061101; P:neuroendocrine cell differentiation; ISS:UniProtKB.::GO:0035567; P:non-canonical Wnt receptor signaling pathway; IMP:ZFIN.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0090037; P:positive regulation of protein kinase C signaling cascade; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; IMP:ZFIN.::GO:0045859; P:regulation of protein kinase activity; IMP:ZFIN. |
