rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O94451 | 727 | PLI1_SCHPO E3 SUMO-protein ligase pli1 OS=Sch... | 447 | 3e-51 | 193 | 32 | 49 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030999; P:linear element assembly; IMP:PomBase.::GO:0016925; P:protein sumoylation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0051983; P:regulation of chromosome segregation; IMP:PomBase.::GO:0000019; P:regulation of mitotic recombination; IMP:PomBase.::GO:0032204; P:regulation of telomere maintenance; IMP:PomBase. | 2 | Q04195 | 904 | SIZ1_YEAST E3 SUMO-protein ligase SIZ1 OS=Sac... | 284 | 9e-34 | 142 | 31 | 50 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005940; C:septin ring; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IMP:SGD. | 3 | Q12216 | 726 | SIZ2_YEAST E3 SUMO-protein ligase SIZ2 OS=Sac... | 338 | 5e-30 | 129 | 29 | 48 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030261; P:chromosome condensation; TAS:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IDA:SGD. | 4 | O75928 | 621 | PIAS2_HUMAN E3 SUMO-protein ligase PIAS2 OS=H... | 530 | 6e-30 | 129 | 26 | 42 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q6AZ28 | 572 | PIAS2_RAT E3 SUMO-protein ligase PIAS2 OS=Rat... | 649 | 7e-30 | 128 | 26 | 40 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035259; F:glucocorticoid receptor binding; IPI:RGD.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:MGI.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q8C5D8 | 621 | PIAS2_MOUSE E3 SUMO-protein ligase PIAS2 OS=M... | 492 | 1e-29 | 127 | 28 | 42 | GO:0016604; C:nuclear body; IDA:MGI.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0016925; P:protein sumoylation; IDA:MGI.::GO:0045667; P:regulation of osteoblast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | O88907 | 651 | PIAS1_MOUSE E3 SUMO-protein ligase PIAS1 OS=M... | 303 | 1e-28 | 125 | 33 | 48 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | O75925 | 651 | PIAS1_HUMAN E3 SUMO-protein ligase PIAS1 OS=H... | 303 | 1e-28 | 125 | 33 | 48 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q9Y6X2 | 628 | PIAS3_HUMAN E3 SUMO-protein ligase PIAS3 OS=H... | 304 | 2e-27 | 121 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q9JM05 | 507 | PIAS4_MOUSE E3 SUMO-protein ligase PIAS4 OS=M... | 297 | 2e-27 | 120 | 30 | 46 | GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 11 | O70260 | 628 | PIAS3_RAT E3 SUMO-protein ligase PIAS3 OS=Rat... | 304 | 2e-27 | 121 | 32 | 46 | GO:0030425; C:dendrite; IDA:RGD.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:RGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0015459; F:potassium channel regulator activity; IDA:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IDA:RGD.::GO:0045838; P:positive regulation of membrane potential; IDA:RGD.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | O54714 | 628 | PIAS3_MOUSE E3 SUMO-protein ligase PIAS3 OS=M... | 304 | 2e-27 | 121 | 32 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q8N2W9 | 510 | PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 OS=H... | 298 | 3e-26 | 116 | 29 | 45 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 14 | Q94361 | 793 | GEI17_CAEEL E3 SUMO-protein ligase gei-17 OS=... | 411 | 9e-22 | 103 | 26 | 43 | | | | | | | | | | | GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.::GO:0019789; F:SUMO ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase. | 15 | Q9ULJ6 | 1067 | ZMIZ1_HUMAN Zinc finger MIZ domain-containing... | 99 | 0.0000000000001 | 78.6 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q6P1E1 | 1072 | ZMIZ1_MOUSE Zinc finger MIZ domain-containing... | 99 | 0.0000000000001 | 78.2 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q8CIE2 | 920 | ZMIZ2_MOUSE Zinc finger MIZ domain-containing... | 97 | 0.000000000001 | 75.1 | 35 | 52 | GO:0043596; C:nuclear replication fork; ISS:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 18 | Q6L4L4 | 875 | SIZ1_ORYSJ E3 SUMO-protein ligase SIZ1 OS=Ory... | 221 | 0.000000000001 | 74.7 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | Q6ASW7 | 813 | SIZ2_ORYSJ E3 SUMO-protein ligase SIZ2 OS=Ory... | 108 | 0.00000000001 | 71.6 | 31 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 20 | Q680Q4 | 884 | SIZ1_ARATH E3 SUMO-protein ligase SIZ1 OS=Ara... | 152 | 0.00000000003 | 70.5 | 28 | 47 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0016036; P:cellular response to phosphate starvation; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010247; P:detection of phosphate ion; IDA:TAIR.::GO:0048589; P:developmental growth; IMP:UniProtKB.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0010286; P:heat acclimation; IMP:UniProtKB.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0010113; P:negative regulation of systemic acquired resistance; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0009787; P:regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0040008; P:regulation of growth; IMP:TAIR.::GO:0090352; P:regulation of nitrate assimilation; IMP:TAIR.::GO:2000070; P:regulation of response to water deprivation; IMP:TAIR.::GO:0010337; P:regulation of salicylic acid metabolic process; IMP:TAIR.::GO:0050826; P:response to freezing; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:UniProtKB. | 21 | Q8NF64 | 920 | ZMIZ2_HUMAN Zinc finger MIZ domain-containing... | 302 | 0.00000007 | 59.7 | 25 | 37 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0043596; C:nuclear replication fork; IDA:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q96C24 | 671 | SYTL4_HUMAN Synaptotagmin-like protein 4 OS=H... | 64 | 0.87 | 36.6 | 30 | 47 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0019898; C:extrinsic to membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB. | 23 | Q7ZXH2 | 238 | NSE2_XENLA E3 SUMO-protein ligase NSE2 OS=Xen... | 53 | 1.7 | 34.7 | 30 | 55 | GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB. | 24 | Q86L54 | 530 | Y2829_DICDI TNF receptor-associated factor fa... | 58 | 2.7 | 34.7 | 28 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 25 | Q05AL1 | 673 | ARMC8_DANRE Armadillo repeat-containing prote... | 57 | 8.1 | 33.5 | 37 | 56 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | |