rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | O43125 | 296 | CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce... | 57 | 0.85 | 36.2 | 28 | 46 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 392 | P50478 | 682 | AMPH_CHICK Amphiphysin OS=Gallus gallus (Chic... | 97 | 0.87 | 36.6 | 28 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:AgBase.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:AgBase. | | | | | | | | | | | | | | | | | | | | | 393 | Q92968 | 403 | PEX13_HUMAN Peroxisomal membrane protein PEX1... | 81 | 0.92 | 36.2 | 27 | 46 | GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB.::GO:0001967; P:suckling behavior; ISS:UniProtKB. | 394 | Q80Y61 | 522 | BI2L2_MOUSE Brain-specific angiogenesis inhib... | 62 | 0.92 | 36.2 | 27 | 45 | GO:0044291; C:cell-cell contact zone; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0016044; P:cellular membrane organization; IDA:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 395 | Q8MJ49 | 214 | OSTF1_PIG Osteoclast-stimulating factor 1 OS=... | 56 | 0.94 | 35.4 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 396 | Q8TE68 | 723 | ES8L1_HUMAN Epidermal growth factor receptor ... | 54 | 0.95 | 36.2 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 397 | Q812A2 | 1099 | SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p... | 99 | 0.98 | 36.6 | 23 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 398 | Q2GT05 | 713 | HSE1_CHAGB Class E vacuolar protein-sorting m... | 85 | 1.1 | 36.2 | 25 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 399 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 53 | 1.1 | 35.4 | 28 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 400 | C5DQY5 | 371 | SHO1_ZYGRC High osmolarity signaling protein ... | 92 | 1.4 | 35.4 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 401 | O94868 | 740 | FCSD2_HUMAN FCH and double SH3 domains protei... | 103 | 6 | 33.9 | 29 | 45 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 402 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 98 | 1.4 | 35.8 | 23 | 43 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 403 | Q9HF75 | 2071 | BEM2_ASHGO GTPase-activating protein BEM2 OS=... | 80 | 1.5 | 35.8 | 25 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 404 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 49 | 1.5 | 35.8 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 405 | Q557J6 | 481 | DBNL_DICDI Drebrin-like protein OS=Dictyostel... | 54 | 1.5 | 35.4 | 31 | 56 | GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase. | 406 | Q9D0K1 | 405 | PEX13_MOUSE Peroxisomal membrane protein PEX1... | 84 | 1.5 | 35.4 | 27 | 45 | | | | | | | | | | | GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI. | 407 | Q3USJ8 | 740 | FCSD2_MOUSE FCH and double SH3 domains protei... | 103 | 7.6 | 33.5 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | | 408 | C5MB30 | 340 | SHO1_CANTT High osmolarity signaling protein ... | 51 | 1.5 | 35.4 | 39 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 409 | P03949 | 1224 | ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=C... | 65 | 1.5 | 35.8 | 28 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IGI:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0030336; P:negative regulation of cell migration; IGI:WormBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:WormBase.::GO:0060101; P:negative regulation of phagocytosis, engulfment; IGI:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 410 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 47 | 1.5 | 35.4 | 40 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 411 | Q8N3R9 | 675 | MPP5_HUMAN MAGUK p55 subfamily member 5 OS=Ho... | 38 | 1.6 | 35.8 | 37 | 63 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:BHF-UCL. | | | | | | | | | | GO:0070830; P:tight junction assembly; TAS:Reactome. | 412 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 54 | 1.6 | 35.4 | 26 | 61 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 413 | Q9JLB2 | 675 | MPP5_MOUSE MAGUK p55 subfamily member 5 OS=Mu... | 53 | 1.7 | 35.4 | 30 | 55 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032287; P:peripheral nervous system myelin maintenance; IMP:BHF-UCL.::GO:0035750; P:protein localization to myelin sheath abaxonal region; IMP:BHF-UCL. | 414 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 54 | 1.7 | 35.4 | 26 | 61 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 415 | Q5RDQ2 | 675 | MPP5_PONAB MAGUK p55 subfamily member 5 OS=Po... | 38 | 1.7 | 35.4 | 37 | 63 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 416 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 53 | 1.7 | 35.8 | 28 | 58 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 417 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 49 | 1.8 | 35.4 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 418 | Q07883 | 217 | GRB2_CHICK Growth factor receptor-bound prote... | 59 | 4.1 | 33.5 | 22 | 47 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 419 | Q5BKC9 | 701 | NGEF_RAT Ephexin-1 OS=Rattus norvegicus (Rat)... | 53 | 1.8 | 35.4 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 420 | Q61140 | 874 | BCAR1_MOUSE Breast cancer anti-estrogen resis... | 41 | 1.8 | 35.4 | 37 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB. | 421 | Q8CHT1 | 710 | NGEF_MOUSE Ephexin-1 OS=Mus musculus (Mouse).... | 55 | 1.8 | 35.4 | 27 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IDA:UniProtKB.::GO:0043087; P:regulation of GTPase activity; IDA:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |