| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A5H0J2 | 1830 | DUR1_LACKL Urea amidolyase OS=Lachancea kluyv... | 47 | 0.0001 | 49.7 | 53 | 68 | | | | | | | | | | | GO:0004039; F:allophanate hydrolase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro. | 32 | Q9KWU4 | 1148 | PYC_BACSU Pyruvate carboxylase OS=Bacillus su... | 140 | 0.00001 | 53.1 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:InterPro. | 33 | P32528 | 1835 | DUR1_YEAST Urea amidolyase OS=Saccharomyces c... | 51 | 0.015 | 42.7 | 37 | 61 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0004039; F:allophanate hydrolase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0000256; P:allantoin catabolic process; TAS:SGD.::GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0043419; P:urea catabolic process; IMP:SGD. | 34 | Q05920 | 1178 | PYC_MOUSE Pyruvate carboxylase, mitochondrial... | 67 | 0.000003 | 55.1 | 45 | 63 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 35 | P52873 | 1178 | PYC_RAT Pyruvate carboxylase, mitochondrial O... | 67 | 0.00003 | 51.6 | 45 | 61 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IDA:RGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IDA:RGD.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.::GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.::GO:0006090; P:pyruvate metabolic process; IDA:RGD. | 36 | P46392 | 598 | BCCA_MYCLE Acetyl-/propionyl-coenzyme A carbo... | 98 | 0.0001 | 49.7 | 33 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 37 | Q29RK2 | 1178 | PYC_BOVIN Pyruvate carboxylase, mitochondrial... | 67 | 0.00002 | 52 | 45 | 61 | GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 38 | P11498 | 1178 | PYC_HUMAN Pyruvate carboxylase, mitochondrial... | 67 | 0.00003 | 51.6 | 45 | 61 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; TAS:Reactome. | | | | | | | | | | GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 39 | P38095 | 1241 | LAMA_EMENI Putative urea carboxylase OS=194 /... | 67 | 0.002 | 45.8 | 39 | 61 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 40 | O17732 | 1175 | PYC1_CAEEL Pyruvate carboxylase 1 OS=Caenorha... | 67 | 0.00004 | 51.2 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 41 | Q9UUE1 | 1185 | PYC_SCHPO Pyruvate carboxylase OS=Schizosacch... | 69 | 0.0001 | 49.3 | 36 | 58 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase. | 42 | P32327 | 1180 | PYC2_YEAST Pyruvate carboxylase 2 OS=Saccharo... | 69 | 0.000002 | 55.8 | 43 | 62 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IMP:SGD. | 43 | Q8X1T3 | 1175 | PYC_PICAN Pyruvate carboxylase OS=Pichia angu... | 66 | 0.064 | 40.8 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 44 | P11154 | 1178 | PYC1_YEAST Pyruvate carboxylase 1 OS=Saccharo... | 67 | 0.000005 | 53.9 | 43 | 60 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IMP:SGD. | 45 | Q0CLK1 | 1193 | PYC_ASPTN Pyruvate carboxylase OS=Aspergillus... | 64 | 0.001 | 46.6 | 42 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 46 | Q9HES8 | 1192 | PYC_ASPNG Pyruvate carboxylase OS=Aspergillus... | 64 | 0.0006 | 47.4 | 42 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 47 | O93918 | 1193 | PYC_ASPTE Pyruvate carboxylase OS=Aspergillus... | 64 | 0.001 | 46.6 | 42 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 48 | P78992 | 1189 | PYC_PICPA Pyruvate carboxylase OS=Pichia past... | 58 | 0.048 | 41.2 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 49 | Q54J08 | 2282 | ACAC_DICDI Acetyl-CoA carboxylase OS=Dictyost... | 561 | 3e-66 | 246 | 33 | 47 | GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005739; C:mitochondrion; ISS:dictyBase. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; ISS:dictyBase.::GO:0006998; P:nuclear envelope organization; ISS:dictyBase.::GO:0006606; P:protein import into nucleus; ISS:dictyBase. | 50 | Q00955 | 2233 | ACAC_YEAST Acetyl-CoA carboxylase OS=Saccharo... | 564 | 2e-64 | 240 | 32 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IMP:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006998; P:nuclear envelope organization; TAS:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD. | 51 | Q5SWU9 | 2345 | ACACA_MOUSE Acetyl-CoA carboxylase 1 OS=Mus m... | 555 | 2e-64 | 240 | 31 | 49 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.::GO:0055088; P:lipid homeostasis; IMP:MGI.::GO:0044268; P:multicellular organismal protein metabolic process; IMP:MGI.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI. | 52 | Q13085 | 2346 | ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo ... | 555 | 3e-64 | 240 | 31 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. | 53 | Q28559 | 2346 | ACACA_SHEEP Acetyl-CoA carboxylase 1 OS=Ovis ... | 555 | 4e-63 | 237 | 30 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB. | 54 | Q9TTS3 | 2346 | ACACA_BOVIN Acetyl-CoA carboxylase 1 OS=Bos t... | 555 | 1e-62 | 235 | 30 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB. | 55 | P11029 | 2324 | ACAC_CHICK Acetyl-CoA carboxylase OS=Gallus g... | 555 | 3e-62 | 234 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 56 | P11497 | 2345 | ACACA_RAT Acetyl-CoA carboxylase 1 OS=Rattus ... | 579 | 4e-62 | 234 | 30 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006084; P:acetyl-CoA metabolic process; IDA:RGD.::GO:0006633; P:fatty acid biosynthetic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IMP:RGD. | 57 | B3LM95 | 2273 | HFA1_YEAS1 Acetyl-CoA carboxylase, mitochondr... | 514 | 3e-61 | 231 | 31 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 58 | C8ZF72 | 2273 | HFA1_YEAS8 Acetyl-CoA carboxylase, mitochondr... | 514 | 6e-61 | 229 | 31 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 59 | C7GRE4 | 2273 | HFA1_YEAS2 Acetyl-CoA carboxylase, mitochondr... | 514 | 7e-61 | 229 | 31 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 60 | A6ZMR9 | 2273 | HFA1_YEAS7 Acetyl-CoA carboxylase, mitochondr... | 514 | 9e-61 | 229 | 31 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 61 | P32874 | 2273 | HFA1_YEAST Acetyl-CoA carboxylase, mitochondr... | 514 | 9e-61 | 229 | 31 | 49 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IGI:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IGI:SGD. |
