rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6R5J1 | 1476 | DISP2_DANRE Protein dispatched homolog 2 OS=D... | 179 | 0.055 | 42 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 32 | P54960 | 856 | HMDH_BLAGE 3-hydroxy-3-methylglutaryl-coenzym... | 77 | 0.16 | 40 | 31 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 33 | P14773 | 920 | HMDH_DROME 3-hydroxy-3-methylglutaryl-coenzym... | 178 | 0.16 | 40 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0018990; P:ecdysis, chitin-based cuticle; IMP:FlyBase.::GO:0035050; P:embryonic heart tube development; IMP:FlyBase.::GO:0035232; P:germ cell attraction; TAS:FlyBase.::GO:0008406; P:gonad development; TAS:FlyBase.::GO:0008299; P:isoprenoid biosynthetic process; TAS:FlyBase.::GO:0007626; P:locomotory behavior; IMP:FlyBase.::GO:0007280; P:pole cell migration; IMP:UniProtKB. | 34 | O74164 | 934 | HMDH_CYBJA 3-hydroxy-3-methylglutaryl-coenzym... | 95 | 0.25 | 39.7 | 37 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 35 | Q3TDN0 | 1521 | DISP1_MOUSE Protein dispatched homolog 1 OS=M... | 77 | 0.56 | 38.5 | 30 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0015197; F:peptide transporter activity; IDA:MGI. | | | | | | | | | | GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0009880; P:embryonic pattern specification; IMP:MGI.::GO:0007225; P:patched ligand maturation; IDA:MGI. | 36 | Q96F81 | 1524 | DISP1_HUMAN Protein dispatched homolog 1 OS=H... | 76 | 0.62 | 38.5 | 22 | 57 | GO:0016323; C:basolateral plasma membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0015197; F:peptide transporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0060539; P:diaphragm development; IMP:UniProtKB.::GO:0070207; P:protein homotrimerization; ISS:UniProtKB.::GO:0050708; P:regulation of protein secretion; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB. | 37 | Q6R5J2 | 1464 | DISP1_DANRE Protein dispatched homolog 1 OS=D... | 76 | 0.93 | 37.7 | 30 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0021984; P:adenohypophysis development; IMP:ZFIN.::GO:0009952; P:anterior/posterior pattern specification; IMP:ZFIN.::GO:0008015; P:blood circulation; IMP:ZFIN.::GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0048839; P:inner ear development; IMP:ZFIN.::GO:0042694; P:muscle cell fate specification; IMP:ZFIN.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:ZFIN.::GO:0007519; P:skeletal muscle tissue development; IMP:ZFIN.::GO:0007224; P:smoothened signaling pathway; IMP:ZFIN. | 38 | Q8CIP5 | 1345 | DISP2_MOUSE Protein dispatched homolog 2 OS=M... | 55 | 1.5 | 37 | 38 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 39 | A7MBM2 | 1401 | DISP2_HUMAN Protein dispatched homolog 2 OS=H... | 64 | 1.9 | 36.6 | 33 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB. | 40 | O76819 | 833 | HMDH_AGRIP 3-hydroxy-3-methylglutaryl-coenzym... | 64 | 2.6 | 36.2 | 31 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW. | 41 | A3KFU9 | 1347 | PTHD2_MOUSE Patched domain-containing protein... | 118 | 2.7 | 36.2 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 42 | Q9P2K9 | 1392 | PTHD2_HUMAN Patched domain-containing protein... | 118 | 2.9 | 36.2 | 23 | 44 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0032368; P:regulation of lipid transport; NAS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB. | 43 | P04035 | 888 | HMDH_HUMAN 3-hydroxy-3-methylglutaryl-coenzym... | 188 | 4 | 35.4 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro. | 44 | Q5R6N3 | 888 | HMDH_PONAB 3-hydroxy-3-methylglutaryl-coenzym... | 178 | 4.1 | 35.4 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. | 45 | Q6D2B0 | 1026 | MDTC_ERWCT Multidrug resistance protein MdtC ... | 67 | 4.2 | 35.4 | 33 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 46 | A7Z064 | 888 | HMDH_BOVIN 3-hydroxy-3-methylglutaryl-coenzym... | 218 | 8.8 | 34.7 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.::GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. |