| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q6PH52 | 424 | PCH2_DANRE Pachytene checkpoint protein 2 hom... | 413 | 3e-99 | 310 | 44 | 61 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 2 | E1C6Q1 | 432 | PCH2_CHICK Pachytene checkpoint protein 2 hom... | 403 | 3e-98 | 308 | 44 | 63 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 3 | Q7XK25 | 471 | PCH2_ORYSJ Pachytene checkpoint protein 2 hom... | 422 | 5e-97 | 306 | 44 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 4 | A2XUN8 | 471 | PCH2_ORYSI Pachytene checkpoint protein 2 hom... | 422 | 5e-97 | 306 | 44 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 5 | Q3UA06 | 432 | PCH2_MOUSE Pachytene checkpoint protein 2 hom... | 402 | 3e-96 | 303 | 43 | 64 | GO:0001673; C:male germ cell nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0007144; P:female meiosis I; IMP:MGI.::GO:0007141; P:male meiosis I; IMP:MGI.::GO:0001556; P:oocyte maturation; IMP:MGI.::GO:0000239; P:pachytene; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IMP:UniProtKB.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB. | 6 | D3K5L7 | 431 | PCH2_PIG Pachytene checkpoint protein 2 homol... | 403 | 4e-96 | 302 | 43 | 64 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 7 | Q5XHZ9 | 432 | PCH2_RAT Pachytene checkpoint protein 2 homol... | 404 | 1e-95 | 301 | 43 | 63 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 8 | Q6P4W8 | 432 | PCH2_XENTR Pachytene checkpoint protein 2 hom... | 403 | 2e-95 | 301 | 43 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 9 | Q15645 | 432 | PCH2_HUMAN Pachytene checkpoint protein 2 hom... | 404 | 5e-95 | 300 | 43 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0003712; F:transcription cofactor activity; TAS:ProtInc. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 10 | Q8H1F9 | 467 | PCH2_ARATH Pachytene checkpoint protein 2 hom... | 404 | 1e-94 | 300 | 43 | 60 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 11 | E2R222 | 432 | PCH2_CANFA Pachytene checkpoint protein 2 hom... | 403 | 2e-94 | 298 | 43 | 64 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB. | 12 | Q09535 | 424 | PCH2_CAEEL Putative pachytene checkpoint prot... | 330 | 2e-70 | 235 | 41 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase. | 13 | P38126 | 564 | PCH2_YEAST Pachytene checkpoint protein 2 OS=... | 315 | 3e-52 | 190 | 35 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; TAS:SGD. | 14 | Q2FQ56 | 412 | PAN_METHJ Proteasome-activating nucleotidase ... | 160 | 0.000000000000003 | 80.9 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 15 | P62198 | 406 | PRS8_RAT 26S protease regulatory subunit 8 OS... | 241 | 0.000000000000003 | 80.9 | 27 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 16 | P62197 | 406 | PRS8_PIG 26S protease regulatory subunit 8 OS... | 241 | 0.000000000000003 | 80.9 | 27 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 17 | P62196 | 406 | PRS8_MOUSE 26S protease regulatory subunit 8 ... | 241 | 0.000000000000003 | 80.9 | 27 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 18 | P62195 | 406 | PRS8_HUMAN 26S protease regulatory subunit 8 ... | 241 | 0.000000000000003 | 80.9 | 27 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:UniProtKB.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043069; P:negative regulation of programmed cell death; NAS:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome. | 19 | P62194 | 406 | PRS8_BOVIN 26S protease regulatory subunit 8 ... | 241 | 0.000000000000003 | 80.9 | 27 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0031531; F:thyrotropin-releasing hormone receptor binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 20 | O05209 | 745 | VAT_THEAC VCP-like ATPase OS=NBRC 15155 / AMR... | 159 | 0.000000000000005 | 81.3 | 35 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | | 21 | Q8IYT4 | 538 | KATL2_HUMAN Katanin p60 ATPase-containing sub... | 160 | 0.000000000000008 | 80.1 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC. | | | | | | | | | | | 22 | O18413 | 405 | PRS8_DROME 26S protease regulatory subunit 8 ... | 241 | 0.00000000000001 | 79 | 26 | 50 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0004175; F:endopeptidase activity; IDA:FlyBase. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. | 23 | P54814 | 402 | PRS8_MANSE 26S protease regulatory subunit 8 ... | 241 | 0.00000000000001 | 79 | 26 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 24 | P46470 | 461 | PRS8_XENLA 26S protease regulatory subunit 8 ... | 235 | 0.00000000000001 | 79.3 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 25 | P52917 | 437 | VPS4_YEAST Vacuolar protein sorting-associate... | 239 | 0.00000000000003 | 78.2 | 29 | 47 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD. | | | | | | | | | | GO:0070676; P:intralumenal vesicle formation; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0051260; P:protein homooligomerization; IDA:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD. | 26 | Q9C5U3 | 419 | PRS8A_ARATH 26S protease regulatory subunit 8... | 235 | 0.00000000000004 | 77.4 | 26 | 48 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 27 | Q94BQ2 | 419 | PRS8B_ARATH 26S protease regulatory subunit 8... | 241 | 0.00000000000005 | 77.4 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 28 | Q9D3R6 | 539 | KATL2_MOUSE Katanin p60 ATPase-containing sub... | 160 | 0.00000000000005 | 77.8 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC. | | | | | | | | | | | 29 | P62193 | 440 | PRS4_RAT 26S protease regulatory subunit 4 OS... | 161 | 0.00000000000008 | 76.6 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:RGD. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 30 | P62192 | 440 | PRS4_MOUSE 26S protease regulatory subunit 4 ... | 161 | 0.00000000000008 | 76.6 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0030163; P:protein catabolic process; IEA:InterPro. | 31 | P62191 | 440 | PRS4_HUMAN 26S protease regulatory subunit 4 ... | 161 | 0.00000000000008 | 76.6 | 32 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; NAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. |
