rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q9H4M7 | 779 | PKHA4_HUMAN Pleckstrin homology domain-contai... | 82 | 0.099 | 41.2 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB. | | | | | | | | | | | 242 | Q54KA7 | 986 | SECG_DICDI Ankyrin repeat, PH and SEC7 domain... | 97 | 0.1 | 41.2 | 28 | 43 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 243 | Q5U2Z7 | 748 | RHG24_RAT Rho GTPase-activating protein 24 OS... | 87 | 0.11 | 40.8 | 31 | 47 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 244 | Q80YW0 | 393 | CYH4_MOUSE Cytohesin-4 OS=Mus musculus (Mouse... | 74 | 0.11 | 40.4 | 32 | 51 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 245 | Q9UIA0 | 394 | CYH4_HUMAN Cytohesin-4 OS=Homo sapiens (Human... | 74 | 0.11 | 40.4 | 32 | 51 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 246 | Q8VC98 | 588 | PKHA4_MOUSE Pleckstrin homology domain-contai... | 82 | 0.13 | 40.4 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 247 | Q21441 | 1066 | KI26L_CAEEL Kinesin-like protein vab-8 OS=Cae... | 315 | 0.18 | 40.4 | 17 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:WormBase.::GO:0008078; P:mesodermal cell migration; IMP:WormBase.::GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0001764; P:neuron migration; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IMP:WormBase.::GO:0035121; P:tail morphogenesis; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 248 | Q69ZL1 | 1399 | FGD6_MOUSE FYVE, RhoGEF and PH domain-contain... | 114 | 0.23 | 40 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 249 | Q8BH49 | 266 | SESQ1_MOUSE Sesquipedalian-1 OS=Mus musculus ... | 79 | 0.23 | 38.9 | 37 | 47 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 250 | Q8C2K1 | 630 | DEFI6_MOUSE Differentially expressed in FDCP ... | 93 | 0.24 | 39.7 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 251 | P60669 | 779 | PKHA4_RAT Pleckstrin homology domain-containi... | 82 | 0.24 | 39.7 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 252 | Q9H4E7 | 631 | DEFI6_HUMAN Differentially expressed in FDCP ... | 93 | 0.26 | 39.7 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 253 | Q8N264 | 748 | RHG24_HUMAN Rho GTPase-activating protein 24 ... | 87 | 0.28 | 39.7 | 30 | 47 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 254 | Q7Z5H3 | 698 | RHG22_HUMAN Rho GTPase-activating protein 22 ... | 39 | 0.33 | 39.3 | 44 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 255 | Q9ZUI0 | 980 | Y2241_ARATH Putative leucine-rich repeat rece... | 89 | 0.37 | 39.3 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 256 | Q8C4V1 | 747 | RHG24_MOUSE Rho GTPase-activating protein 24 ... | 87 | 0.57 | 38.5 | 30 | 47 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 257 | Q9VLW2 | 1131 | KI26L_DROME Kinesin-like protein CG14535 OS=D... | 397 | 0.84 | 38.1 | 21 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro. | | | | | | | | | | GO:0007018; P:microtubule-based movement; IEA:InterPro. | 258 | Q96M96 | 766 | FGD4_HUMAN FYVE, RhoGEF and PH domain-contain... | 76 | 0.87 | 38.1 | 30 | 47 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 259 | Q1KKZ1 | 329 | SKAP2_TAKRU Src kinase-associated phosphoprot... | 81 | 0.95 | 37.4 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 260 | Q8N4B1 | 249 | SESQ1_HUMAN Sesquipedalian-1 OS=Homo sapiens ... | 99 | 1.1 | 37 | 26 | 40 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0001881; P:receptor recycling; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB. | 261 | P54644 | 444 | KRAC_DICDI RAC family serine/threonine-protei... | 75 | 1.2 | 37.4 | 29 | 55 | GO:0005938; C:cell cortex; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase. | 262 | B4K6T8 | 1925 | DGKH_DROMO Diacylglycerol kinase eta OS=Droso... | 98 | 1.2 | 37.7 | 29 | 49 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 263 | Q8BL80 | 702 | RHG22_MOUSE Rho GTPase-activating protein 22 ... | 35 | 1.4 | 37.4 | 46 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 264 | Q969H4 | 720 | CNKR1_HUMAN Connector enhancer of kinase supp... | 78 | 1.6 | 37 | 31 | 47 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005911; C:cell-cell junction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IDA:MGI. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; IPI:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 265 | P42331 | 645 | RHG25_HUMAN Rho GTPase-activating protein 25 ... | 85 | 2.1 | 36.6 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 266 | Q8A6A7 | 201 | RUVA_BACTN Holliday junction ATP-dependent DN... | 80 | 2.1 | 35.8 | 26 | 54 | GO:0009379; C:Holliday junction helicase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. | 267 | B4JHJ7 | 1941 | DGKH_DROGR Diacylglycerol kinase eta OS=Droso... | 101 | 2.5 | 36.6 | 29 | 49 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 268 | Q6ZV73 | 1430 | FGD6_HUMAN FYVE, RhoGEF and PH domain-contain... | 114 | 2.7 | 36.6 | 26 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 269 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 141 | 3.1 | 35.8 | 21 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 270 | Q924H7 | 646 | WAC_MOUSE WW domain-containing adapter protei... | 52 | 3.1 | 36.2 | 38 | 54 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB. | | | | | | | | | | GO:0000075; P:cell cycle checkpoint; ISS:UniProtKB.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 271 | Q86IV4 | 458 | Y4775_DICDI PH domain-containing protein DDB_... | 78 | 3.5 | 35.8 | 29 | 46 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | |