rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O74732 | 338 | ERG27_SCHPO 3-keto-steroid reductase OS=Schiz... | 367 | 7e-37 | 142 | 29 | 44 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase. | 2 | Q6CJC2 | 346 | ERG27_KLULA 3-keto-steroid reductase OS=1267 ... | 372 | 2e-33 | 132 | 26 | 44 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 3 | Q12452 | 347 | ERG27_YEAST 3-keto-steroid reductase OS=Sacch... | 360 | 1e-31 | 127 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 4 | Q6FIV3 | 348 | ERG27_CANGA 3-keto-steroid reductase OS=NRRL ... | 371 | 1e-30 | 124 | 26 | 45 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 5 | Q874K0 | 346 | ERG27_CANAX 3-keto-steroid reductase OS=Candi... | 318 | 3e-30 | 123 | 27 | 46 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 6 | Q6BNP0 | 346 | ERG27_DEBHA 3-keto-steroid reductase OS=0083 ... | 369 | 3e-30 | 123 | 27 | 43 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 7 | Q74ZZ0 | 348 | ERG27_ASHGO 3-keto-steroid reductase OS=Y-105... | 316 | 3e-30 | 123 | 29 | 46 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 8 | Q6CE88 | 343 | ERG27_YARLI 3-keto-steroid reductase OS=lipol... | 380 | 1e-25 | 109 | 25 | 42 | | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 9 | Q62904 | 334 | DHB7_RAT 3-keto-steroid reductase OS=Rattus n... | 396 | 5e-24 | 104 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005148; F:prolactin receptor binding; IMP:RGD. | | | | | | | | | | | 10 | P56937 | 341 | DHB7_HUMAN 3-keto-steroid reductase OS=Homo s... | 363 | 2e-23 | 103 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 11 | O88736 | 334 | DHB7_MOUSE 3-keto-steroid reductase OS=Mus mu... | 402 | 1e-21 | 98.2 | 23 | 41 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IDA:MGI. | 12 | P48758 | 277 | CBR1_MOUSE Carbonyl reductase [NADPH] 1 OS=Mu... | 223 | 0.001 | 44.3 | 26 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 13 | Q9HBH5 | 336 | RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo ... | 243 | 0.01 | 41.2 | 25 | 40 | GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q9ERI6 | 334 | RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus m... | 262 | 0.026 | 40 | 24 | 37 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 220 | 0.038 | 39.7 | 22 | 36 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 16 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 219 | 0.053 | 39.3 | 21 | 35 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 17 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 141 | 0.11 | 38.1 | 25 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 18 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 247 | 0.14 | 37.7 | 22 | 38 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 19 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 247 | 0.24 | 37 | 22 | 38 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 20 | P40801 | 689 | GAL10_PACTA Bifunctional protein GAL10 OS=Pac... | 60 | 1.4 | 35 | 33 | 52 | | | | | | | | | | | GO:0004034; F:aldose 1-epimerase activity; IEA:EC.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:EC. | | | | | | | | | | GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW. | 21 | P47844 | 277 | CBR1_RABIT Carbonyl reductase [NADPH] 1 OS=Or... | 60 | 2.4 | 33.5 | 35 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 22 | Q28960 | 289 | CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ... | 57 | 2.9 | 33.5 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 23 | P47727 | 277 | CBR1_RAT Carbonyl reductase [NADPH] 1 OS=Ratt... | 60 | 3.5 | 33.1 | 33 | 50 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0001542; P:ovulation from ovarian follicle; IEP:RGD.::GO:0018205; P:peptidyl-lysine modification; NAS:RGD.::GO:0042376; P:phylloquinone catabolic process; IDA:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 24 | Q8SRZ0 | 457 | PP1L_ENCCU Probable serine/threonine-protein ... | 67 | 4.1 | 33.1 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 25 | Q559Z0 | 356 | NDUA9_DICDI NADH dehydrogenase [ubiquinone] 1... | 69 | 5.8 | 32.7 | 25 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005747; C:mitochondrial respiratory chain complex I; ISS:dictyBase. | | | | | | | | | | GO:0003954; F:NADH dehydrogenase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; ISS:dictyBase. | 26 | P85112 | 89 | KPPR_VITSX Phosphoribulokinase, chloroplastic... | 52 | 6 | 30.4 | 37 | 50 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008974; F:phosphoribulokinase activity; IEA:EC. | | | | | | | | | | GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-KW. | 27 | Q02789 | 1880 | CAC1S_MOUSE Voltage-dependent L-type calcium ... | 76 | 9.9 | 32.3 | 30 | 43 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | |