rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P56590 | 524 | CP1A1_CANFA Cytochrome P450 1A1 OS=Canis fami... | 469 | 1e-32 | 134 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 62 | Q96418 | 510 | C75A5_EUSER Flavonoid 3',5'-hydroxylase OS=gr... | 489 | 1e-32 | 133 | 25 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 63 | O04790 | 510 | C75A7_EUSER Flavonoid 3',5'-hydroxylase OS=gr... | 478 | 1e-32 | 133 | 26 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 64 | P79760 | 530 | CP1A4_CHICK Cytochrome P450 1A4 OS=Gallus gal... | 474 | 2e-32 | 133 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 65 | Q01361 | 500 | CP2DE_BOVIN Cytochrome P450 2D14 OS=Bos tauru... | 497 | 2e-32 | 132 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 66 | Q29510 | 489 | CP2CU_RABIT Cytochrome P450 2C30 OS=Oryctolag... | 472 | 2e-32 | 132 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 67 | P56655 | 490 | CP238_MOUSE Cytochrome P450 2C38 OS=Mus muscu... | 470 | 3e-32 | 132 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 68 | Q64680 | 500 | CP2DI_RAT Cytochrome P450 2D18 OS=Rattus norv... | 519 | 3e-32 | 132 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IMP:RGD. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0042416; P:dopamine biosynthetic process; IDA:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0010033; P:response to organic substance; IEP:RGD. | 69 | P33260 | 490 | CP2CI_HUMAN Cytochrome P450 2C18 OS=Homo sapi... | 459 | 4e-32 | 132 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 70 | O18963 | 495 | CP2E1_BOVIN Cytochrome P450 2E1 OS=Bos taurus... | 498 | 7e-32 | 131 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 71 | P05181 | 493 | CP2E1_HUMAN Cytochrome P450 2E1 OS=Homo sapie... | 467 | 7e-32 | 131 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 72 | P11714 | 504 | CP2D9_MOUSE Cytochrome P450 2D9 OS=Mus muscul... | 471 | 7e-32 | 131 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 73 | Q6GUQ4 | 493 | CP2E1_MACMU Cytochrome P450 2E1 OS=Macaca mul... | 490 | 7e-32 | 131 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 74 | Q08078 | 490 | CP2CP_MESAU Cytochrome P450 2C25 OS=Mesocrice... | 493 | 7e-32 | 131 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 75 | Q91X77 | 490 | CY250_MOUSE Cytochrome P450 2C50 OS=Mus muscu... | 508 | 8e-32 | 131 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 76 | P19225 | 489 | CP270_RAT Cytochrome P450 2C70 OS=Rattus norv... | 511 | 9e-32 | 130 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; NAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 77 | Q4H4C3 | 516 | CP1A2_MACFU Cytochrome P450 1A2 OS=Macaca fus... | 461 | 1e-31 | 130 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 78 | P56656 | 490 | CP239_MOUSE Cytochrome P450 2C39 OS=Mus muscu... | 466 | 1e-31 | 130 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 79 | Q9SD85 | 513 | F3PH_ARATH Flavonoid 3'-monooxygenase OS=Arab... | 487 | 2e-31 | 130 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016711; F:flavonoid 3'-monooxygenase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.::GO:0009733; P:response to auxin stimulus; IEP:TAIR. | 80 | P05182 | 493 | CP2E1_RAT Cytochrome P450 2E1 OS=Rattus norve... | 487 | 2e-31 | 130 | 25 | 44 | GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0010181; F:FMN binding; IC:RGD.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IDA:RGD. | | | | | | | | | | GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0010193; P:response to ozone; IEP:RGD.::GO:0006641; P:triglyceride metabolic process; IMP:RGD.::GO:0006805; P:xenobiotic metabolic process; IMP:RGD. | 81 | P00184 | 524 | CP1A1_MOUSE Cytochrome P450 1A1 OS=Mus muscul... | 496 | 2e-31 | 130 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009308; P:amine metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI. | 82 | P00187 | 516 | CP1A2_RABIT Cytochrome P450 1A2 OS=Oryctolagu... | 510 | 2e-31 | 130 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 83 | P11712 | 490 | CP2C9_HUMAN Cytochrome P450 2C9 OS=Homo sapie... | 461 | 3e-31 | 129 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0052741; F:(R)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018675; F:(S)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018676; F:(S)-limonene 7-monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL. | | | | | | | | | | GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0019627; P:urea metabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 84 | P33265 | 490 | CP2CS_MESAU Cytochrome P450 2C28 OS=Mesocrice... | 418 | 3e-31 | 129 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 85 | Q00557 | 524 | CP1A1_MESAU Cytochrome P450 1A1 OS=Mesocricet... | 476 | 3e-31 | 129 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 86 | P11371 | 487 | CP2C4_RABIT Cytochrome P450 2C4 OS=Oryctolagu... | 466 | 4e-31 | 129 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 87 | P79761 | 528 | CP1A5_CHICK Cytochrome P450 1A5 OS=Gallus gal... | 434 | 5e-31 | 129 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 88 | P08682 | 493 | CP2E1_RABIT Cytochrome P450 2E1 OS=Oryctolagu... | 462 | 6e-31 | 128 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 89 | P33273 | 490 | CP255_RAT Cytochrome P450 2C55 OS=Rattus norv... | 461 | 6e-31 | 128 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 90 | P20814 | 490 | CP2CD_RAT Cytochrome P450 2C13, male-specific... | 482 | 6e-31 | 128 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 91 | Q9MZY0 | 494 | CP2E1_CANFA Cytochrome P450 2E1 OS=Canis fami... | 501 | 9e-31 | 128 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | |