rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | A1CFB3 | 1406 | ATG26_ASPCL Sterol 3-beta-glucosyltransferase... | 106 | 0.0006 | 46.6 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 92 | Q8C4V1 | 747 | RHG24_MOUSE Rho GTPase-activating protein 24 ... | 36 | 0.38 | 37.4 | 42 | 56 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 93 | Q86UU1 | 1377 | PHLB1_HUMAN Pleckstrin homology-like domain f... | 34 | 0.28 | 37.7 | 44 | 68 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 94 | Q5U2Z7 | 748 | RHG24_RAT Rho GTPase-activating protein 24 OS... | 36 | 0.81 | 36.2 | 42 | 56 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 95 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 119 | 0.0008 | 45.1 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 96 | Q8N4B1 | 249 | SESQ1_HUMAN Sesquipedalian-1 OS=Homo sapiens ... | 95 | 0.0009 | 44.7 | 32 | 48 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0001881; P:receptor recycling; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB. | 97 | Q6PG29 | 341 | SKAP2_DANRE Src kinase-associated phosphoprot... | 129 | 0.001 | 45.1 | 32 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 98 | P42331 | 645 | RHG25_HUMAN Rho GTPase-activating protein 25 ... | 40 | 0.21 | 38.1 | 40 | 60 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 99 | Q8BYW1 | 648 | RHG25_MOUSE Rho GTPase-activating protein 25 ... | 50 | 0.18 | 38.1 | 38 | 58 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 100 | A2BID5 | 813 | MELT_DANRE Ventricular zone-expressed PH doma... | 126 | 0.001 | 45.4 | 30 | 47 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IMP:ZFIN.::GO:0042471; P:ear morphogenesis; IMP:ZFIN. | 101 | Q16760 | 1214 | DGKD_HUMAN Diacylglycerol kinase delta OS=Hom... | 92 | 0.001 | 45.4 | 33 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.::GO:0004143; F:diacylglycerol kinase activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0042803; F:protein homodimerization activity; IDA:MGI. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0046339; P:diacylglycerol metabolic process; NAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010033; P:response to organic substance; IDA:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB. | 102 | Q6ZPE2 | 1867 | MTMR5_MOUSE Myotubularin-related protein 5 OS... | 96 | 0.001 | 45.4 | 31 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0001691; F:pseudophosphatase activity; TAS:MGI. | | | | | | | | | | GO:0001558; P:regulation of cell growth; TAS:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 103 | Q552C1 | 1555 | Y9957_DICDI Probable serine/threonine-protein... | 75 | 0.047 | 40.4 | 32 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 104 | P0CN90 | 1585 | ATG26_CRYNJ Sterol 3-beta-glucosyltransferase... | 163 | 0.001 | 45.4 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 105 | O95248 | 1867 | MTMR5_HUMAN Myotubularin-related protein 5 OS... | 96 | 0.001 | 45.4 | 31 | 44 | GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; TAS:UniProtKB. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; TAS:UniProtKB. | 106 | P0CN91 | 1585 | ATG26_CRYNB Sterol 3-beta-glucosyltransferase... | 163 | 0.001 | 45.1 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 107 | Q14644 | 834 | RASA3_HUMAN Ras GTPase-activating protein 3 O... | 107 | 0.002 | 44.7 | 25 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 108 | Q55GV3 | 477 | PAKC_DICDI Serine/threonine-protein kinase pa... | 96 | 0.002 | 44.3 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0031273; P:negative regulation of pseudopodium assembly; IMP:dictyBase. | 109 | D3ZL52 | 234 | SESQ1_RAT Sesquipedalian-1 OS=Rattus norvegic... | 96 | 0.002 | 43.1 | 32 | 51 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 110 | Q6NSJ2 | 640 | PHLB3_HUMAN Pleckstrin homology-like domain f... | 101 | 0.003 | 44.3 | 28 | 45 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 111 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 119 | 0.003 | 43.5 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 112 | Q86WG5 | 1849 | MTMRD_HUMAN Myotubularin-related protein 13 O... | 96 | 0.003 | 44.3 | 34 | 48 | | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0042552; P:myelination; NAS:UniProtKB. | 113 | Q5PQS3 | 832 | MELT_RAT Ventricular zone-expressed PH domain... | 125 | 0.003 | 43.9 | 30 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 114 | Q9ST43 | 145 | PH1_ARATH Pleckstrin homology domain-containi... | 57 | 0.092 | 37.4 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 115 | Q60790 | 834 | RASA3_MOUSE Ras GTPase-activating protein 3 O... | 107 | 0.003 | 43.9 | 23 | 50 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 116 | Q9QYJ2 | 834 | RASA3_RAT Ras GTPase-activating protein 3 OS=... | 107 | 0.004 | 43.9 | 23 | 50 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 117 | B3LXF2 | 1916 | DGKH_DROAN Diacylglycerol kinase eta OS=Droso... | 104 | 0.004 | 43.9 | 24 | 53 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 118 | P22059 | 807 | OSBP1_HUMAN Oxysterol-binding protein 1 OS=Ho... | 145 | 0.004 | 43.5 | 22 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008142; F:oxysterol binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 119 | P16258 | 809 | OSBP1_RABIT Oxysterol-binding protein 1 OS=Or... | 145 | 0.005 | 43.5 | 22 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 120 | A7ERM5 | 1435 | ATG26_SCLS1 Sterol 3-beta-glucosyltransferase... | 104 | 0.005 | 43.5 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 121 | Q6ZV73 | 1430 | FGD6_HUMAN FYVE, RhoGEF and PH domain-contain... | 95 | 1.3 | 35.4 | 32 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. |