rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A6QLU3 | 694 | GAB1_BOVIN GRB2-associated-binding protein 1 ... | 106 | 0.0000005 | 56.2 | 32 | 48 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 32 | Q5F4B2 | 586 | SWP70_CHICK Switch-associated protein 70 OS=G... | 42 | 0.027 | 40.8 | 43 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 33 | Q9NGQ2 | 2205 | KIF1_DICDI Kinesin-related protein 1 OS=Dicty... | 34 | 5.3 | 33.5 | 41 | 53 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007018; P:microtubule-based movement; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 34 | Q9JHK5 | 350 | PLEK_MOUSE Pleckstrin OS=Mus musculus (Mouse)... | 95 | 0.06 | 39.3 | 28 | 47 | | | | | | | | | | | | | | | | | | | | | GO:0070527; P:platelet aggregation; IMP:BHF-UCL.::GO:0030836; P:positive regulation of actin filament depolymerization; IMP:BHF-UCL.::GO:0033625; P:positive regulation of integrin activation; IMP:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; IMP:BHF-UCL.::GO:0070528; P:protein kinase C signaling cascade; IMP:BHF-UCL.::GO:0070560; P:protein secretion by platelet; IMP:BHF-UCL.::GO:0070493; P:thrombin receptor signaling pathway; IMP:BHF-UCL.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:BHF-UCL. | 35 | Q9NYT0 | 353 | PLEK2_HUMAN Pleckstrin-2 OS=Homo sapiens (Hum... | 33 | 0.36 | 37 | 39 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 36 | Q8C115 | 1491 | PKHH2_MOUSE Pleckstrin homology domain-contai... | 39 | 0.01 | 42.4 | 41 | 67 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 37 | Q8BSM5 | 595 | GAB3_MOUSE GRB2-associated-binding protein 3 ... | 135 | 0.051 | 40 | 26 | 41 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0030225; P:macrophage differentiation; IDA:MGI. | 38 | Q6Q308 | 351 | PLEK_CANFA Pleckstrin OS=Canis familiaris (Do... | 36 | 0.35 | 37 | 42 | 61 | | | | | | | | | | | | | | | | | | | | | | 39 | B4JHJ7 | 1941 | DGKH_DROGR Diacylglycerol kinase eta OS=Droso... | 136 | 0.036 | 40.8 | 24 | 40 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 40 | Q9WV52 | 353 | PLEK2_MOUSE Pleckstrin-2 OS=Mus musculus (Mou... | 33 | 0.5 | 36.6 | 39 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 41 | Q86IV4 | 458 | Y4775_DICDI PH domain-containing protein DDB_... | 42 | 0.001 | 45.1 | 45 | 57 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 42 | Q7SYB5 | 612 | DEFI6_DANRE Differentially expressed in FDCP ... | 42 | 0.023 | 41.2 | 48 | 57 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042074; P:cell migration involved in gastrulation; IMP:ZFIN.::GO:0060027; P:convergent extension involved in gastrulation; IMP:ZFIN. | 43 | Q54KA7 | 986 | SECG_DICDI Ankyrin repeat, PH and SEC7 domain... | 50 | 0.004 | 43.9 | 32 | 66 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 44 | Q9W5D0 | 1820 | Y34F_DROME Uncharacterized protein CG42248 OS... | 85 | 0.0001 | 48.9 | 34 | 52 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 45 | P08567 | 350 | PLEK_HUMAN Pleckstrin OS=Homo sapiens (Human)... | 94 | 0.011 | 41.6 | 29 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.::GO:0032587; C:ruffle membrane; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; IDA:BHF-UCL. | | | | | | | | | | GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005080; F:protein kinase C binding; IDA:BHF-UCL. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.::GO:0030866; P:cortical actin cytoskeleton organization; IDA:BHF-UCL.::GO:0002244; P:hemopoietic progenitor cell differentiation; IEP:BHF-UCL.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IDA:BHF-UCL.::GO:0007229; P:integrin-mediated signaling pathway; IDA:BHF-UCL.::GO:0050849; P:negative regulation of calcium-mediated signaling; NAS:BHF-UCL.::GO:0010920; P:negative regulation of inositol phosphate biosynthetic process; IDA:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; IDA:BHF-UCL.::GO:0070527; P:platelet aggregation; ISS:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0030836; P:positive regulation of actin filament depolymerization; IDA:BHF-UCL.::GO:0010925; P:positive regulation of inositol-polyphosphate 5-phosphatase activity; IDA:BHF-UCL.::GO:0033625; P:positive regulation of integrin activation; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0070528; P:protein kinase C signaling cascade; ISS:BHF-UCL.::GO:0070560; P:protein secretion by platelet; ISS:BHF-UCL.::GO:0060305; P:regulation of cell diameter; IDA:BHF-UCL.::GO:0031529; P:ruffle organization; IDA:BHF-UCL.::GO:0070493; P:thrombin receptor signaling pathway; IDA:BHF-UCL.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:BHF-UCL. | 46 | Q0UY53 | 1453 | ATG26_PHANO Sterol 3-beta-glucosyltransferase... | 116 | 0.000005 | 53.1 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 47 | Q8IVE3 | 1493 | PKHH2_HUMAN Pleckstrin homology domain-contai... | 39 | 0.004 | 43.9 | 44 | 69 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 48 | Q96P50 | 834 | ACAP3_HUMAN Arf-GAP with coiled-coil, ANK rep... | 161 | 1.2 | 35.4 | 22 | 40 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 49 | Q2WGN9 | 574 | GAB4_HUMAN GRB2-associated-binding protein 4 ... | 149 | 0.016 | 41.6 | 21 | 38 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 50 | Q1ZXL0 | 808 | Y5795_DICDI PH domain-containing protein DDB_... | 62 | 0.003 | 43.9 | 39 | 55 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 51 | Q6PA69 | 596 | DEFI6_XENLA Differentially expressed in FDCP ... | 31 | 1.1 | 35.4 | 45 | 61 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 52 | Q7S1I0 | 1553 | ATG26_NEUCR Sterol 3-beta-glucosyltransferase... | 101 | 0.000008 | 52.4 | 29 | 51 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 53 | Q4KM33 | 350 | PLEK_RAT Pleckstrin OS=Rattus norvegicus (Rat... | 95 | 0.034 | 40 | 28 | 47 | | | | | | | | | | | | | | | | | | | | | | 54 | Q6NTN5 | 1873 | MTMRD_XENLA Myotubularin-related protein 13 O... | 98 | 0.00001 | 52 | 34 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 55 | B4K6T8 | 1925 | DGKH_DROMO Diacylglycerol kinase eta OS=Droso... | 104 | 0.00001 | 51.6 | 26 | 56 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 56 | Q6IVG4 | 778 | ACAP2_RABIT Arf-GAP with coiled-coil, ANK rep... | 167 | 0.22 | 38.1 | 22 | 38 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 57 | Q2U0C3 | 1384 | ATG26_ASPOR Sterol 3-beta-glucosyltransferase... | 106 | 0.00002 | 51.2 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 58 | Q15057 | 778 | ACAP2_HUMAN Arf-GAP with coiled-coil, ANK rep... | 167 | 0.25 | 37.7 | 22 | 38 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 59 | Q80YA9 | 1032 | CNKR2_MOUSE Connector enhancer of kinase supp... | 185 | 0.00002 | 51.2 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 60 | Q5FVC7 | 770 | ACAP2_RAT Arf-GAP with coiled-coil, ANK repea... | 67 | 0.31 | 37.4 | 27 | 49 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 61 | Q8WXI2 | 1034 | CNKR2_HUMAN Connector enhancer of kinase supp... | 185 | 0.00002 | 50.8 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. |