| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q940Y1 | 721 | ORP2A_ARATH Oxysterol-binding protein-related... | 133 | 2 | 34.7 | 24 | 39 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 242 | Q9Z268 | 799 | RASL1_MOUSE RasGAP-activating-like protein 1 ... | 142 | 2 | 35 | 27 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 243 | Q91ZT5 | 766 | FGD4_MOUSE FYVE, RhoGEF and PH domain-contain... | 96 | 2.3 | 34.7 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 244 | O14340 | 1310 | YB35_SCHPO Oxysterol-binding protein homolog ... | 45 | 3.2 | 34.3 | 36 | 58 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005783; C:endoplasmic reticulum; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; ISS:PomBase.::GO:0008142; F:oxysterol binding; ISS:PomBase. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006629; P:lipid metabolic process; NAS:PomBase.::GO:0015918; P:sterol transport; ISS:PomBase. | 245 | Q9ERS4 | 297 | PKHA3_MOUSE Pleckstrin homology domain-contai... | 100 | 2.4 | 34.3 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI. | | | | | | | | | | | 246 | Q54WS5 | 2147 | ROCO6_DICDI Probable serine/threonine-protein... | 98 | 2.4 | 34.7 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 247 | Q8WZ64 | 1704 | ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 99 | 4.5 | 33.9 | 25 | 38 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 248 | O08684 | 1036 | PLD1_CRIGR Phospholipase D1 OS=Cricetulus gri... | 78 | 3.1 | 34.3 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004630; F:phospholipase D activity; IEA:EC. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 249 | Q9SMX5 | 775 | AGD4_ARATH ADP-ribosylation factor GTPase-act... | 200 | 3.1 | 34.3 | 25 | 39 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 250 | Q17941 | 541 | AKT1_CAEEL Serine/threonine-protein kinase ak... | 35 | 3.2 | 34.3 | 37 | 63 | GO:0005622; C:intracellular; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:WormBase. | 251 | Q90738 | 729 | AFAP1_CHICK Actin filament-associated protein... | 38 | 3.5 | 33.9 | 37 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 252 | O88387 | 766 | FGD4_RAT FYVE, RhoGEF and PH domain-containin... | 96 | 3.5 | 33.9 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:MGI.::GO:0008360; P:regulation of cell shape; IMP:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 253 | Q9Z280 | 1074 | PLD1_MOUSE Phospholipase D1 OS=Mus musculus (... | 78 | 3.7 | 33.9 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004630; F:phospholipase D activity; IEA:EC. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 254 | Q54KV6 | 570 | GPA3_DICDI Guanine nucleotide-binding protein... | 35 | 3.8 | 33.9 | 43 | 63 | GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome. | | | | | | | | | | GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IBA:RefGenome. | | | | | | | | | | GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IBA:RefGenome. | 255 | Q8R2V5 | 381 | ADAP2_MOUSE Arf-GAP with dual PH domain-conta... | 122 | 3.9 | 33.5 | 25 | 45 | GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; NAS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 256 | Q7SIG6 | 958 | ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe... | 109 | 4.2 | 33.9 | 23 | 42 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 257 | P70496 | 1074 | PLD1_RAT Phospholipase D1 OS=Rattus norvegicu... | 78 | 4.4 | 33.9 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031985; C:Golgi cisterna; IDA:RGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031982; C:vesicle; IDA:RGD. | | | | | | | | | | GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004630; F:phospholipase D activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006654; P:phosphatidic acid biosynthetic process; IMP:MGI.::GO:0009395; P:phospholipid catabolic process; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IMP:RGD. | 258 | Q8N556 | 730 | AFAP1_HUMAN Actin filament-associated protein... | 38 | 4.5 | 33.9 | 37 | 55 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 259 | O43150 | 1006 | ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe... | 109 | 4.5 | 33.9 | 23 | 42 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 260 | Q28CB1 | 943 | TBD2B_XENTR TBC1 domain family member 2B OS=X... | 112 | 4.9 | 33.5 | 27 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 261 | P46941 | 837 | TG325_CAEEL WW domain-containing protein tag-... | 69 | 4.9 | 33.5 | 29 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 262 | Q8L751 | 814 | ORP1C_ARATH Oxysterol-binding protein-related... | 138 | 5 | 33.5 | 26 | 41 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 263 | Q5U464 | 904 | ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe... | 100 | 5.4 | 33.5 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 264 | Q9LRZ5 | 1096 | PLDP1_ARATH Phospholipase D p1 OS=Arabidopsis... | 92 | 5.5 | 33.5 | 27 | 47 | | | | | | | | | | | GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0004630; F:phospholipase D activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0048364; P:root development; IGI:TAIR. | 265 | Q9JLM9 | 538 | GRB14_MOUSE Growth factor receptor-bound prot... | 100 | 5.8 | 33.1 | 30 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:MGI. | | | | | | | | | | | 266 | Q29EP6 | 1235 | JIP3_DROPS JNK-interacting protein 3 OS=Droso... | 221 | 6.1 | 33.5 | 23 | 43 | GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0005078; F:MAP-kinase scaffold activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0008088; P:axon cargo transport; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB. | 267 | Q6IP76 | 485 | AKT2B_XENLA RAC-beta serine/threonine-protein... | 102 | 6.2 | 33.1 | 27 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 268 | Q9UF11 | 243 | PKHB1_HUMAN Pleckstrin homology domain-contai... | 120 | 6.9 | 32.7 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007602; P:phototransduction; NAS:UniProtKB. | 269 | Q9GQF1 | 1227 | JIP3_DROME JNK-interacting protein 3 OS=Droso... | 220 | 7.3 | 33.1 | 23 | 43 | GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:FlyBase. | | | | | | | | | | GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0005078; F:MAP-kinase scaffold activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0008088; P:axon cargo transport; IMP:FlyBase.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEP:UniProtKB. | 270 | Q9QWN8 | 2388 | SPTN2_RAT Spectrin beta chain, brain 2 OS=Rat... | 157 | 7.5 | 33.1 | 27 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016363; C:nuclear matrix; TAS:UniProtKB.::GO:0008091; C:spectrin; TAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; TAS:UniProtKB.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; TAS:UniProtKB. | 271 | Q13393 | 1074 | PLD1_HUMAN Phospholipase D1 OS=Homo sapiens (... | 78 | 7.9 | 33.1 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004630; F:phospholipase D activity; TAS:ProtInc. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. |
