| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9BWF2 | 469 | TRAIP_HUMAN TRAF-interacting protein OS=Homo ... | 61 | 0.0004 | 43.1 | 39 | 51 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc. | 2 | Q8VIG6 | 470 | TRAIP_MOUSE TRAF-interacting protein OS=Mus m... | 61 | 0.0008 | 42.4 | 38 | 51 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005057; F:receptor signaling protein activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 3 | Q9NZS9 | 450 | BFAR_HUMAN Bifunctional apoptosis regulator O... | 49 | 0.013 | 38.5 | 35 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005198; F:structural molecule activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 4 | Q1MTQ0 | 692 | BRL1_SCHPO E3 ubiquitin-protein ligase brl1 O... | 47 | 0.02 | 38.1 | 36 | 55 | GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase. | 5 | Q5PQN2 | 450 | BFAR_RAT Bifunctional apoptosis regulator OS=... | 49 | 0.03 | 37.7 | 33 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 6 | Q8R079 | 450 | BFAR_MOUSE Bifunctional apoptosis regulator O... | 49 | 0.032 | 37.4 | 33 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 7 | P46824 | 508 | KLC_DROME Kinesin light chain OS=Drosophila m... | 81 | 0.036 | 37.4 | 30 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005871; C:kinesin complex; IEA:InterPro.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003777; F:microtubule motor activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007018; P:microtubule-based movement; IDA:FlyBase. | 8 | Q84JU6 | 927 | HOS1_ARATH E3 ubiquitin-protein ligase HOS1 O... | 54 | 0.037 | 37.4 | 30 | 57 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IEP:TAIR.::GO:0009409; P:response to cold; IMP:TAIR. | 9 | Q86KL1 | 1080 | BRE1_DICDI Probable E3 ubiquitin-protein liga... | 57 | 0.044 | 37.4 | 32 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 10 | Q9UTL9 | 1375 | YIV5_SCHPO Uncharacterized ATP-dependent heli... | 56 | 0.047 | 37.4 | 34 | 48 | GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:PomBase. | 11 | Q6GNY1 | 1011 | MIB1_XENLA E3 ubiquitin-protein ligase mib1 O... | 27 | 2.7 | 32 | 44 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 12 | P87176 | 269 | SLX8_SCHPO E3 ubiquitin-protein ligase comple... | 44 | 0.088 | 36.2 | 43 | 50 | GO:0033768; C:SUMO-targeted ubiquitin ligase complex; IPI:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006310; P:DNA recombination; IGI:PomBase.::GO:0033234; P:negative regulation of protein sumoylation; IMP:PomBase. | 13 | Q60YN5 | 828 | BRE1_CAEBR E3 ubiquitin-protein ligase bre-1 ... | 57 | 0.088 | 36.2 | 32 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 14 | Q8IS11 | 944 | GEFO_DICDI Ras guanine nucleotide exchange fa... | 51 | 0.098 | 36.2 | 35 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 15 | P34537 | 837 | BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 ... | 57 | 0.099 | 36.2 | 32 | 47 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006664; P:glycolipid metabolic process; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 16 | Q4WDD7 | 725 | BRE1_ASPFU E3 ubiquitin-protein ligase bre1 O... | 48 | 0.13 | 35.8 | 33 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 17 | Q8BFU3 | 668 | RN214_MOUSE RING finger protein 214 OS=Mus mu... | 45 | 0.15 | 35.8 | 38 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 18 | Q2U9B0 | 760 | BRE1_ASPOR E3 ubiquitin-protein ligase bre1 O... | 48 | 0.17 | 35.4 | 33 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 19 | P19474 | 475 | RO52_HUMAN E3 ubiquitin-protein ligase TRIM21... | 42 | 0.18 | 35.4 | 45 | 60 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB. | 20 | Q9M9Y4 | 421 | DRIP1_ARATH E3 ubiquitin protein ligase DRIP1... | 50 | 0.18 | 35.4 | 36 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB. | 21 | Q804S5 | 1030 | MIB1_DANRE E3 ubiquitin-protein ligase mib1 O... | 27 | 2.5 | 32 | 44 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 22 | Q62191 | 470 | RO52_MOUSE E3 ubiquitin-protein ligase TRIM21... | 143 | 0.19 | 35.4 | 27 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 23 | Q7YRV4 | 469 | RO52_BOVIN E3 ubiquitin-protein ligase TRIM21... | 42 | 0.19 | 35 | 43 | 60 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 24 | Q86YT6 | 1006 | MIB1_HUMAN E3 ubiquitin-protein ligase MIB1 O... | 45 | 1.7 | 32.3 | 38 | 49 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; TAS:Reactome. | 25 | Q8IUD6 | 432 | RN135_HUMAN E3 ubiquitin-protein ligase RNF13... | 48 | 0.2 | 35 | 40 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0045088; P:regulation of innate immune response; IMP:UniProtKB. | 26 | Q8RXD6 | 878 | BRE1A_ARATH E3 ubiquitin-protein ligase BRE1-... | 48 | 0.21 | 35.4 | 33 | 48 | GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0033523; P:histone H2B ubiquitination; IMP:TAIR.::GO:0010390; P:histone monoubiquitination; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0010162; P:seed dormancy process; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR. | 27 | Q6TEM9 | 472 | MYLIA_DANRE E3 ubiquitin-protein ligase MYLIP... | 42 | 0.25 | 35 | 40 | 62 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB. | 28 | Q9FY48 | 1625 | KEG_ARATH E3 ubiquitin-protein ligase KEG OS=... | 47 | 0.32 | 34.7 | 38 | 49 | GO:0005769; C:early endosome; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0006952; P:defense response; IMP:TAIR.::GO:0048589; P:developmental growth; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR. | 29 | Q5R581 | 560 | KLC1_PONAB Kinesin light chain 1 OS=Pongo abe... | 103 | 0.36 | 34.3 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005871; C:kinesin complex; IEA:InterPro.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro. | | | | | | | | | | | 30 | Q07866 | 573 | KLC1_HUMAN Kinesin light chain 1 OS=Homo sapi... | 103 | 0.36 | 34.3 | 26 | 49 | GO:0005829; C:cytosol; ISS:HGNC.::GO:0005871; C:kinesin complex; ISS:HGNC.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0035617; P:stress granule disassembly; ISS:BHF-UCL. | 31 | P15539 | 500 | C11B2_MOUSE Cytochrome P450 11B2, mitochondri... | 122 | 0.37 | 34.3 | 28 | 46 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:MGI. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IDA:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0050801; P:ion homeostasis; IMP:MGI.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:MGI.::GO:0001991; P:regulation of systemic arterial blood pressure by circulatory renin-angiotensin; IMP:MGI. |
