| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P81529 | 114 | MIFH_TRISP Macrophage migration inhibitory fa... | 109 | 0.000000000001 | 63.9 | 32 | 49 | GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | | 2 | P91850 | 115 | MIFH_BRUMA Macrophage migration inhibitory fa... | 101 | 0.00000000003 | 60.5 | 31 | 56 | GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | | 3 | Q1ZZU7 | 115 | MIF_SHEEP Macrophage migration inhibitory fac... | 109 | 0.000000001 | 55.8 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 4 | P80177 | 115 | MIF_BOVIN Macrophage migration inhibitory fac... | 109 | 0.000000001 | 55.8 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 5 | Q6DN04 | 115 | MIF_MACMU Macrophage migration inhibitory fac... | 109 | 0.000000005 | 53.9 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 6 | Q4R549 | 115 | MIF_MACFA Macrophage migration inhibitory fac... | 109 | 0.000000005 | 53.9 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 7 | P14174 | 115 | MIF_HUMAN Macrophage migration inhibitory fac... | 109 | 0.000000005 | 53.9 | 29 | 49 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043498; F:cell surface binding; IDA:BHF-UCL.::GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.::GO:0005125; F:cytokine activity; IDA:UniProtKB.::GO:0005126; F:cytokine receptor binding; IPI:BHF-UCL.::GO:0004167; F:dopachrome isomerase activity; IDA:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IDA:MGI. | | | | | | | | | | GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0090344; P:negative regulation of cell aging; IDA:BHF-UCL.::GO:0071157; P:negative regulation of cell cycle arrest; IDA:BHF-UCL.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0010629; P:negative regulation of gene expression; IDA:BHF-UCL.::GO:0030890; P:positive regulation of B cell proliferation; IDA:BHF-UCL.::GO:0050715; P:positive regulation of cytokine secretion; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0010739; P:positive regulation of protein kinase A signaling cascade; IDA:BHF-UCL.::GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.::GO:0070207; P:protein homotrimerization; IPI:UniProtKB.::GO:0043030; P:regulation of macrophage activation; NAS:UniProtKB. | 8 | P80928 | 115 | MIF_PIG Macrophage migration inhibitory facto... | 109 | 0.000000006 | 53.9 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 9 | P30904 | 115 | MIF_RAT Macrophage migration inhibitory facto... | 109 | 0.000000008 | 53.5 | 28 | 49 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0002035; P:brain renin-angiotensin system; IMP:RGD.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0042756; P:drinking behavior; IMP:RGD.::GO:0001942; P:hair follicle development; IEP:RGD.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0002675; P:positive regulation of acute inflammatory response; IMP:RGD.::GO:0048680; P:positive regulation of axon regeneration; IMP:RGD.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0045821; P:positive regulation of glycolysis; IMP:RGD.::GO:0050778; P:positive regulation of immune response; IMP:RGD.::GO:0043268; P:positive regulation of potassium ion transport; IMP:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0032572; P:response to menaquinone; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0043588; P:skin development; IEP:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD.::GO:0042060; P:wound healing; IEP:RGD. | 10 | Q640C5 | 118 | DOPDB_XENLA D-dopachrome decarboxylase-B OS=X... | 109 | 0.00000001 | 53.1 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 11 | P34884 | 115 | MIF_MOUSE Macrophage migration inhibitory fac... | 109 | 0.00000001 | 53.1 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:BHF-UCL. | | | | | | | | | | GO:0005125; F:cytokine activity; IDA:BHF-UCL.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IMP:MGI. | | | | | | | | | | GO:0007569; P:cell aging; IMP:MGI.::GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IMP:MGI.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0032269; P:negative regulation of cellular protein metabolic process; IDA:BHF-UCL.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0002906; P:negative regulation of mature B cell apoptotic process; IDA:BHF-UCL.::GO:0033033; P:negative regulation of myeloid cell apoptotic process; IMP:BHF-UCL.::GO:0002821; P:positive regulation of adaptive immune response; NAS:BHF-UCL.::GO:0090238; P:positive regulation of arachidonic acid secretion; IDA:BHF-UCL.::GO:2000343; P:positive regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:BHF-UCL.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0061081; P:positive regulation of myeloid leukocyte cytokine production involved in immune response; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0061078; P:positive regulation of prostaglandin secretion involved in immune response; IMP:BHF-UCL. | 12 | Q28J83 | 118 | DOPD_XENTR D-dopachrome decarboxylase OS=Xeno... | 109 | 0.00000004 | 51.6 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 13 | O44786 | 115 | MIFH_WUCBA Macrophage migration inhibitory fa... | 102 | 0.00000004 | 51.6 | 29 | 51 | GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | | 14 | Q02960 | 115 | MIF_CHICK Macrophage migration inhibitory fac... | 109 | 0.00000004 | 51.6 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 15 | O55052 | 115 | MIF_MERUN Macrophage migration inhibitory fac... | 109 | 0.00000005 | 51.2 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 16 | Q68FI3 | 118 | DOPDA_XENLA D-dopachrome decarboxylase-A OS=X... | 109 | 0.00000006 | 50.8 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 17 | A9JSE7 | 115 | MIF_XENTR Macrophage migration inhibitory fac... | 109 | 0.0000001 | 50.1 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 18 | P81748 | 114 | MIFH_TRITR Macrophage migration inhibitory fa... | 109 | 0.0000003 | 48.9 | 30 | 43 | GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | | 19 | P30046 | 118 | DOPD_HUMAN D-dopachrome decarboxylase OS=Homo... | 111 | 0.000001 | 47.4 | 30 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC.::GO:0004167; F:dopachrome isomerase activity; TAS:ProtInc. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 20 | Q76BK2 | 115 | MIF_XENLA Macrophage migration inhibitory fac... | 109 | 0.000003 | 46.2 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.::GO:0004167; F:dopachrome isomerase activity; IEA:EC.::GO:0050178; F:phenylpyruvate tautomerase activity; IEA:EC. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 21 | Q5ZMG0 | 118 | DOPD_CHICK D-dopachrome decarboxylase OS=Gall... | 109 | 0.000003 | 45.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 22 | A6NHG4 | 134 | DDTL_HUMAN D-dopachrome decarboxylase-like pr... | 106 | 0.00002 | 44.3 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 23 | A5PK65 | 118 | DOPD_BOVIN D-dopachrome decarboxylase OS=Bos ... | 109 | 0.00004 | 42.7 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 24 | O35215 | 118 | DOPD_MOUSE D-dopachrome decarboxylase OS=Mus ... | 109 | 0.0002 | 41.2 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 25 | P80254 | 118 | DOPD_RAT D-dopachrome decarboxylase OS=Rattus... | 109 | 0.0003 | 40.8 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033981; F:D-dopachrome decarboxylase activity; IEA:EC.::GO:0004167; F:dopachrome isomerase activity; TAS:RGD. | | | | | | | | | | GO:0006954; P:inflammatory response; NAS:RGD.::GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 26 | Q9P6Q3 | 449 | BCS1_SCHPO Probable mitochondrial chaperone b... | 34 | 0.07 | 35.4 | 38 | 68 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:PomBase. | | | | | | | | | | GO:0043623; P:cellular protein complex assembly; ISS:PomBase.::GO:0016226; P:iron-sulfur cluster assembly; ISS:PomBase. | 27 | P0CO41 | 879 | JHD1_CRYNB JmjC domain-containing histone dem... | 34 | 2.6 | 30.8 | 38 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | P0CO40 | 879 | JHD1_CRYNJ JmjC domain-containing histone dem... | 34 | 2.7 | 30.8 | 38 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | P45251 | 284 | KDSA_HAEIN 2-dehydro-3-deoxyphosphooctonate a... | 60 | 3.9 | 30.4 | 33 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:EC. | | | | | | | | | | GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW. | 30 | Q4QKR7 | 284 | KDSA_HAEI8 2-dehydro-3-deoxyphosphooctonate a... | 60 | 3.9 | 30.4 | 33 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:EC. | | | | | | | | | | GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW. | 31 | A5UEF6 | 284 | KDSA_HAEIG 2-dehydro-3-deoxyphosphooctonate a... | 60 | 4.3 | 30 | 33 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:EC. | | | | | | | | | | GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW. |
