rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q5XIT0 | 507 | CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R... | 309 | 7e-29 | 124 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 242 | P18265 | 483 | GSK3A_RAT Glycogen synthase kinase-3 alpha OS... | 308 | 7e-29 | 123 | 30 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 243 | P83101 | 501 | GSK3H_DROME Putative glycogen synthase kinase... | 304 | 7e-29 | 124 | 31 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0048232; P:male gamete generation; IMP:FlyBase. | 244 | Q4WUN7 | 378 | MPKC_ASPFU Mitogen-activated protein kinase m... | 306 | 7e-29 | 122 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 245 | Q8GYQ5 | 372 | MPK12_ARATH Mitogen-activated protein kinase ... | 302 | 7e-29 | 122 | 31 | 51 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0080026; P:response to indolebutyric acid stimulus; IMP:TAIR. | 246 | Q5YJC2 | 420 | GSK3B_SPECI Glycogen synthase kinase-3 beta O... | 229 | 7e-29 | 122 | 34 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 247 | P40417 | 426 | ERKA_DROME Mitogen-activated protein kinase E... | 319 | 7e-29 | 122 | 29 | 48 | GO:0030054; C:cell junction; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:FlyBase.::GO:0019901; F:protein kinase binding; IPI:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0007369; P:gastrulation; NAS:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0046534; P:positive regulation of photoreceptor cell differentiation; IMP:FlyBase.::GO:0045467; P:R7 cell development; TAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase.::GO:0050804; P:regulation of synaptic transmission; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase. | 248 | Q40531 | 371 | NTF6_TOBAC Mitogen-activated protein kinase h... | 347 | 8e-29 | 122 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 249 | Q91757 | 420 | GSK3B_XENLA Glycogen synthase kinase-3 beta O... | 228 | 8e-29 | 122 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 250 | P16892 | 353 | FUS3_YEAST Mitogen-activated protein kinase F... | 307 | 8e-29 | 121 | 30 | 48 | GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IPI:SGD.::GO:0010526; P:negative regulation of transposition, RNA-mediated; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IDA:SGD. | 251 | Q39022 | 376 | MPK2_ARATH Mitogen-activated protein kinase 2... | 308 | 9e-29 | 121 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 252 | Q9WV60 | 420 | GSK3B_MOUSE Glycogen synthase kinase-3 beta O... | 228 | 1e-28 | 122 | 33 | 55 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB. | 253 | Q39023 | 370 | MPK3_ARATH Mitogen-activated protein kinase 3... | 322 | 1e-28 | 121 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0000169; P:activation of MAPK activity involved in osmosensory signaling pathway; IDA:TAIR.::GO:0010120; P:camalexin biosynthetic process; IMP:TAIR.::GO:0048481; P:ovule development; IGI:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0080136; P:priming of cellular response to stress; IMP:TAIR.::GO:2000038; P:regulation of stomatal complex development; IGI:TAIR.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR.::GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006970; P:response to osmotic stress; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0010224; P:response to UV-B; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR. | 254 | Q39026 | 395 | MPK6_ARATH Mitogen-activated protein kinase 6... | 304 | 1e-28 | 122 | 31 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0009574; C:preprophase band; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0010120; P:camalexin biosynthetic process; IMP:TAIR.::GO:0051301; P:cell division; IMP:TAIR.::GO:0009864; P:induced systemic resistance, jasmonic acid mediated signaling pathway; IMP:TAIR.::GO:0048481; P:ovule development; IGI:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0080136; P:priming of cellular response to stress; IMP:TAIR.::GO:2000038; P:regulation of stomatal complex development; IGI:TAIR.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009409; P:response to cold; IDA:TAIR.::GO:0009723; P:response to ethylene stimulus; IDA:TAIR.::GO:0042542; P:response to hydrogen peroxide; IDA:TAIR.::GO:0009651; P:response to salt stress; IGI:TAIR.::GO:0010224; P:response to UV-B; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR. | 255 | P49841 | 420 | GSK3B_HUMAN Glycogen synthase kinase-3 beta O... | 228 | 1e-28 | 122 | 33 | 55 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IC:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.::GO:0021766; P:hippocampus development; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL. | 256 | Q8TD08 | 544 | MK15_HUMAN Mitogen-activated protein kinase 1... | 313 | 1e-28 | 124 | 28 | 49 | GO:0005576; C:extracellular region; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; NAS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 257 | Q4Z6R1 | 288 | CDC2H_PLABA Cell division control protein 2 h... | 311 | 1e-28 | 120 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 258 | Q8W4P1 | 513 | CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Ar... | 310 | 1e-28 | 123 | 28 | 49 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0016604; C:nuclear body; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0048440; P:carpel development; IGI:TAIR.::GO:0048366; P:leaf development; IGI:TAIR.::GO:0006397; P:mRNA processing; IEP:TAIR.::GO:0050792; P:regulation of viral reproduction; IMP:TAIR.::GO:0009615; P:response to virus; IEP:TAIR. | 259 | A3EZ54 | 278 | HOG1_WALSE Mitogen-activated protein kinase H... | 219 | 1e-28 | 119 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 260 | P24033 | 302 | CDK1B_XENLA Cyclin-dependent kinase 1-B OS=Xe... | 306 | 2e-28 | 119 | 29 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 261 | Q45FA5 | 426 | SRPK_PHYPO Serine/threonine-protein kinase SR... | 372 | 2e-28 | 121 | 25 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 262 | P28482 | 360 | MK01_HUMAN Mitogen-activated protein kinase 1... | 325 | 2e-28 | 120 | 30 | 48 | GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 263 | Q00532 | 357 | CDKL1_HUMAN Cyclin-dependent kinase-like 1 OS... | 330 | 2e-28 | 120 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc. | | | | | | | | | | | 264 | P63086 | 358 | MK01_RAT Mitogen-activated protein kinase 1 O... | 325 | 2e-28 | 120 | 30 | 48 | GO:0033267; C:axon part; IDA:RGD.::GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000189; P:MAPK import into nucleus; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IEP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IEP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IDA:RGD.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB. | 265 | P63085 | 358 | MK01_MOUSE Mitogen-activated protein kinase 1... | 325 | 2e-28 | 120 | 30 | 48 | GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:MGI.::GO:0001784; F:phosphotyrosine binding; IMP:MGI.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0019858; P:cytosine metabolic process; IDA:MGI.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IDA:MGI.::GO:0045596; P:negative regulation of cell differentiation; IGI:MGI.::GO:0009887; P:organ morphogenesis; IDA:MGI.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB. | 266 | P46196 | 360 | MK01_BOVIN Mitogen-activated protein kinase 1... | 325 | 3e-28 | 120 | 30 | 48 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 267 | P43063 | 317 | CDK1_CANAL Cyclin-dependent kinase 1 OS=Candi... | 312 | 3e-28 | 119 | 27 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:CGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:CGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IGI:CGD. | 268 | Q3TZA2 | 342 | CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS... | 325 | 3e-28 | 119 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 269 | Q06060 | 394 | MAPK_PEA Mitogen-activated protein kinase hom... | 297 | 3e-28 | 120 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 270 | Q40518 | 409 | MSK1_TOBAC Shaggy-related protein kinase NtK-... | 303 | 3e-28 | 120 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 271 | Q17446 | 377 | PMK1_CAEEL Mitogen-activated protein kinase p... | 308 | 3e-28 | 120 | 30 | 49 | GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:WormBase. | | | | | | | | | | GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0012501; P:programmed cell death; IMP:WormBase. |