rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O74184 | 314 | WAT1_SCHPO WD repeat-containing protein wat1 ... | 306 | 5e-145 | 418 | 63 | 79 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 2 | P41318 | 303 | LST8_YEAST Target of rapamycin complex subuni... | 307 | 2e-131 | 384 | 60 | 76 | GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD. | 3 | Q54D08 | 304 | LST8_DICDI Protein LST8 homolog OS=Dictyostel... | 305 | 5e-107 | 321 | 51 | 69 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase. | 4 | Q803V5 | 326 | LST8_DANRE Target of rapamycin complex subuni... | 318 | 3e-88 | 274 | 45 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 5 | Q5I0B4 | 326 | LST8_XENTR Target of rapamycin complex subuni... | 314 | 1e-86 | 270 | 44 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 6 | Q6PA72 | 326 | LST8_XENLA Target of rapamycin complex subuni... | 314 | 1e-86 | 270 | 44 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 7 | Q17QU5 | 326 | LST8_BOVIN Target of rapamycin complex subuni... | 317 | 5e-86 | 268 | 44 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 8 | Q9BVC4 | 326 | LST8_HUMAN Target of rapamycin complex subuni... | 317 | 2e-85 | 267 | 44 | 62 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 9 | Q9DCJ1 | 326 | LST8_MOUSE Target of rapamycin complex subuni... | 317 | 2e-84 | 264 | 44 | 62 | | | | | | | | | | | | | | | | | | | | | GO:0030838; P:positive regulation of actin filament polymerization; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI. | 10 | Q9Z2K5 | 326 | LST8_RAT Target of rapamycin complex subunit ... | 317 | 4e-83 | 261 | 43 | 61 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | | | | | | | | | | | | 11 | Q9W328 | 313 | LST8_DROME Protein LST8 homolog OS=Drosophila... | 308 | 8e-74 | 236 | 40 | 57 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 12 | Q29HG9 | 315 | LST8_DROPS Protein LST8 homolog OS=Drosophila... | 309 | 1e-70 | 228 | 39 | 56 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 13 | O13982 | 399 | YEC8_SCHPO Uncharacterized WD repeat-containi... | 256 | 3e-16 | 82 | 28 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0000027; P:ribosomal large subunit assembly; ISS:PomBase. | 14 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 243 | 0.000000000000002 | 79 | 26 | 45 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 233 | 0.0000000000002 | 73.6 | 24 | 43 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 233 | 0.0000000000002 | 73.6 | 24 | 43 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 233 | 0.0000000000002 | 73.6 | 24 | 43 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 233 | 0.0000000000002 | 73.6 | 24 | 43 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q6P5M2 | 305 | WDR61_DANRE WD repeat-containing protein 61 O... | 283 | 0.000000000001 | 70.9 | 22 | 41 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 20 | Q54S59 | 299 | WDR61_DICDI WD repeat-containing protein 61 h... | 248 | 0.000000000004 | 69.3 | 24 | 42 | | | | | | | | | | | | | | | | | | | | | | 21 | Q9V3J8 | 361 | WDS_DROME Protein will die slowly OS=Drosophi... | 233 | 0.000000000005 | 69.7 | 24 | 43 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase. | 22 | Q6ZMY6 | 472 | WDR88_HUMAN WD repeat-containing protein 88 O... | 245 | 0.000000000007 | 69.7 | 23 | 43 | | | | | | | | | | | | | | | | | | | | | | 23 | A9V790 | 410 | LIS1_MONBE Lissencephaly-1 homolog OS=Monosig... | 279 | 0.00000000001 | 68.9 | 23 | 44 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 24 | O16519 | 620 | GAD1_CAEEL Gastrulation defective protein 1 O... | 235 | 0.00000000002 | 68.6 | 27 | 45 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0042074; P:cell migration involved in gastrulation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:WormBase. | 25 | Q91WQ5 | 589 | TAF5L_MOUSE TAF5-like RNA polymerase II p300/... | 266 | 0.0000000001 | 65.5 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q6PBD6 | 305 | WDR61_XENTR WD repeat-containing protein 61 O... | 283 | 0.0000000002 | 64.7 | 23 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 27 | O76734 | 579 | TUP1_DICDI General transcriptional corepresso... | 199 | 0.0000000003 | 64.7 | 28 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q6GMD2 | 305 | WDR61_XENLA WD repeat-containing protein 61 O... | 283 | 0.0000000003 | 63.9 | 23 | 42 | GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 29 | Q8YV57 | 1683 | Y2124_NOSS1 Uncharacterized WD repeat-contain... | 140 | 0.0000000004 | 64.7 | 25 | 48 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 30 | Q99M63 | 513 | SMU1_RAT WD40 repeat-containing protein SMU1 ... | 247 | 0.0000000004 | 63.9 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 31 | Q3UKJ7 | 513 | SMU1_MOUSE WD40 repeat-containing protein SMU... | 247 | 0.0000000005 | 63.9 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | |