| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q61194 | 1686 | P3C2A_MOUSE Phosphatidylinositol 4-phosphate ... | 304 | 1e-27 | 125 | 32 | 48 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:MGI.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 32 | O00443 | 1686 | P3C2A_HUMAN Phosphatidylinositol 4-phosphate ... | 305 | 3e-27 | 124 | 31 | 48 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0048268; P:clathrin coat assembly; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0006887; P:exocytosis; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0014829; P:vascular smooth muscle contraction; TAS:UniProtKB. | 33 | Q5RAY1 | 1685 | P3C2A_PONAB Phosphatidylinositol 4-phosphate ... | 293 | 1e-26 | 122 | 31 | 48 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 34 | O70173 | 1505 | P3C2G_RAT Phosphatidylinositol 4-phosphate 3-... | 239 | 2e-26 | 121 | 33 | 51 | GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005635; C:nuclear envelope; IDA:RGD.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 35 | O75747 | 1445 | P3C2G_HUMAN Phosphatidylinositol 4-phosphate ... | 202 | 2e-26 | 121 | 36 | 52 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 36 | P54673 | 1571 | PI3K1_DICDI Phosphatidylinositol 3-kinase 1 O... | 277 | 7e-26 | 119 | 28 | 48 | GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:dictyBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0006928; P:cellular component movement; IGI:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IGI:dictyBase.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:dictyBase.::GO:0050919; P:negative chemotaxis; IGI:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045761; P:regulation of adenylate cyclase activity; IMP:dictyBase.::GO:0022604; P:regulation of cell morphogenesis; IGI:dictyBase.::GO:0051591; P:response to cAMP; IGI:dictyBase. | 37 | P54674 | 1857 | PI3K2_DICDI Phosphatidylinositol 3-kinase 2 O... | 271 | 2e-25 | 118 | 28 | 49 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006928; P:cellular component movement; IGI:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IGI:dictyBase.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:dictyBase.::GO:0050919; P:negative chemotaxis; IGI:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0045761; P:regulation of adenylate cyclase activity; IMP:dictyBase.::GO:0022604; P:regulation of cell morphogenesis; IGI:dictyBase.::GO:0051591; P:response to cAMP; IGI:dictyBase. | 38 | O00750 | 1634 | P3C2B_HUMAN Phosphatidylinositol 4-phosphate ... | 306 | 3e-25 | 117 | 29 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 39 | P42347 | 814 | PI3K1_SOYBN Phosphatidylinositol 3-kinase, ro... | 273 | 1e-24 | 114 | 30 | 47 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 40 | P54676 | 816 | PI3K4_DICDI Phosphatidylinositol 3-kinase VPS... | 236 | 1e-24 | 114 | 33 | 51 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 41 | P42348 | 812 | PI3K2_SOYBN Phosphatidylinositol 3-kinase, no... | 273 | 3e-24 | 113 | 30 | 47 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 42 | P48736 | 1102 | PK3CG_HUMAN Phosphatidylinositol 4,5-bisphosp... | 306 | 3e-24 | 114 | 27 | 48 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0001816; P:cytokine production; TAS:UniProtKB.::GO:0002407; P:dendritic cell chemotaxis; TAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0043303; P:mast cell degranulation; TAS:UniProtKB.::GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.::GO:0055118; P:negative regulation of cardiac muscle contraction; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0070527; P:platelet aggregation; TAS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; TAS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.::GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.::GO:0042098; P:T cell proliferation; TAS:UniProtKB. | 43 | Q6PF93 | 887 | PK3C3_MOUSE Phosphatidylinositol 3-kinase cat... | 380 | 1e-23 | 111 | 26 | 45 | GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IMP:MGI. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB. | 44 | P50520 | 801 | VPS34_SCHPO Phosphatidylinositol 3-kinase vps... | 261 | 3e-23 | 110 | 32 | 51 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IC:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:PomBase.::GO:0031321; P:ascospore-type prospore assembly; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0007033; P:vacuole organization; IMP:PomBase.::GO:0016192; P:vesicle-mediated transport; TAS:PomBase. | 45 | Q8BTI9 | 1064 | PK3CB_MOUSE Phosphatidylinositol 4,5-bisphosp... | 266 | 3e-23 | 110 | 30 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IPI:MGI.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0040016; P:embryonic cleavage; IMP:MGI.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007156; P:homophilic cell adhesion; IMP:MGI.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:MGI. | 46 | O02697 | 1102 | PK3CG_PIG Phosphatidylinositol 4,5-bisphospha... | 283 | 4e-23 | 110 | 27 | 48 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 47 | O88763 | 887 | PK3C3_RAT Phosphatidylinositol 3-kinase catal... | 381 | 4e-23 | 110 | 27 | 45 | GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; IMP:RGD.::GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:RGD.::GO:0016485; P:protein processing; IMP:RGD.::GO:0050708; P:regulation of protein secretion; IMP:RGD.::GO:0043201; P:response to leucine; IEP:RGD. | 48 | Q8NEB9 | 887 | PK3C3_HUMAN Phosphatidylinositol 3-kinase cat... | 377 | 4e-23 | 109 | 26 | 45 | GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome. | 49 | Q9Z1L0 | 1070 | PK3CB_RAT Phosphatidylinositol 4,5-bisphospha... | 266 | 5e-23 | 110 | 30 | 47 | GO:0031526; C:brush border membrane; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IDA:RGD. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 50 | Q9JHG7 | 1102 | PK3CG_MOUSE Phosphatidylinositol 4,5-bisphosp... | 270 | 5e-23 | 109 | 27 | 49 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 51 | Q5D891 | 887 | PK3C3_PIG Phosphatidylinositol 3-kinase catal... | 377 | 7e-23 | 109 | 26 | 45 | GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 52 | Q6AZN6 | 886 | PK3C3_XENLA Phosphatidylinositol 3-kinase cat... | 289 | 1e-22 | 108 | 27 | 46 | GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 53 | P42339 | 814 | PI3K_ARATH Phosphatidylinositol 3-kinase VPS3... | 271 | 2e-22 | 107 | 29 | 48 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IDA:TAIR.::GO:0055046; P:microgametogenesis; IMP:TAIR.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR. | 54 | O00329 | 1044 | PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosp... | 236 | 4e-22 | 106 | 32 | 48 | GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0035754; P:B cell chemotaxis; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0001816; P:cytokine production; TAS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002551; P:mast cell chemotaxis; TAS:UniProtKB.::GO:0043303; P:mast cell degranulation; TAS:UniProtKB.::GO:0060374; P:mast cell differentiation; TAS:UniProtKB.::GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.::GO:0001779; P:natural killer cell differentiation; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0006468; P:protein phosphorylation; NAS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.::GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.::GO:0030217; P:T cell differentiation; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB. | 55 | P42338 | 1070 | PK3CB_HUMAN Phosphatidylinositol 4,5-bisphosp... | 266 | 5e-22 | 106 | 30 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:ProtInc.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0070527; P:platelet aggregation; TAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 56 | O35904 | 1043 | PK3CD_MOUSE Phosphatidylinositol 4,5-bisphosp... | 236 | 5e-22 | 106 | 32 | 48 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC. | | | | | | | | | | GO:0042113; P:B cell activation; IMP:MGI.::GO:0001782; P:B cell homeostasis; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; IMP:MGI.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 57 | P22543 | 875 | VPS34_YEAST Phosphatidylinositol 3-kinase VPS... | 258 | 5e-21 | 103 | 28 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD.::GO:0034271; C:phosphatidylinositol 3-kinase complex I; IDA:SGD.::GO:0034272; C:phosphatidylinositol 3-kinase complex II; IDA:SGD.::GO:0000407; C:pre-autophagosomal structure; IDA:SGD. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 58 | P42336 | 1068 | PK3CA_HUMAN Phosphatidylinositol 4,5-bisphosp... | 214 | 1e-17 | 92.4 | 28 | 48 | | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; TAS:Reactome.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0060048; P:cardiac muscle contraction; TAS:UniProtKB.::GO:0043542; P:endothelial cell migration; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 59 | P32871 | 1068 | PK3CA_BOVIN Phosphatidylinositol 4,5-bisphosp... | 214 | 1e-17 | 92.4 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 60 | P42337 | 1068 | PK3CA_MOUSE Phosphatidylinositol 4,5-bisphosp... | 268 | 2e-17 | 92 | 26 | 45 | GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IPI:MGI. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IPI:MGI.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0044029; P:hypomethylation of CpG island; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.::GO:2000653; P:regulation of genetic imprinting; IDA:BHF-UCL.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI. | 61 | P0C5E7 | 1159 | AGE1_CAEBR Phosphatidylinositol 3-kinase age-... | 215 | 7e-17 | 90.1 | 26 | 47 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; ISS:UniProtKB.::GO:0040024; P:dauer larval development; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. |
