| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | C0LGD8 | 864 | Y1755_ARATH Probable LRR receptor-like serine... | 196 | 0.042 | 39.3 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 452 | P20786 | 1088 | PGFRA_RAT Platelet-derived growth factor rece... | 198 | 0.043 | 39.3 | 23 | 36 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB.::GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0042063; P:gliogenesis; IEP:RGD.::GO:0048839; P:inner ear development; IEP:RGD.::GO:0001553; P:luteinization; ISS:UniProtKB.::GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.::GO:0010544; P:negative regulation of platelet activation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000739; P:regulation of mesenchymal stem cell differentiation; ISS:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010035; P:response to inorganic substance; IEP:RGD.::GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB. | 453 | Q93VD3 | 482 | CIPKN_ARATH CBL-interacting serine/threonine-... | 96 | 0.044 | 38.9 | 28 | 42 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IPI:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0010107; P:potassium ion import; IMP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR. | 454 | Q8TDC3 | 778 | BRSK1_HUMAN Serine/threonine-protein kinase B... | 179 | 0.044 | 39.3 | 24 | 36 | GO:0030054; C:cell junction; IDA:HPA.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IC:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB. | 455 | Q8CFH6 | 931 | SIK2_MOUSE Serine/threonine-protein kinase SI... | 83 | 0.044 | 39.3 | 24 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IDA:UniProtKB. | 456 | Q6P6U0 | 517 | FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus... | 90 | 0.045 | 38.9 | 32 | 48 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB. | 457 | Q5QNM6 | 511 | CIPKD_ORYSJ Putative CBL-interacting protein ... | 147 | 0.046 | 38.9 | 24 | 37 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 458 | Q09136 | 385 | AAPK1_PIG 5'-AMP-activated protein kinase cat... | 182 | 0.046 | 38.9 | 24 | 40 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 459 | Q5UNT1 | 545 | YL673_MIMIV Putative serine/threonine-protein... | 150 | 0.046 | 38.9 | 29 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 460 | P68182 | 351 | KAPCB_RAT cAMP-dependent protein kinase catal... | 100 | 0.046 | 38.9 | 32 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IC:RGD. | | | | | | | | | | GO:0051447; P:negative regulation of meiotic cell cycle; IDA:RGD. | 461 | P68181 | 351 | KAPCB_MOUSE cAMP-dependent protein kinase cat... | 100 | 0.046 | 38.9 | 32 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB. | 462 | P68180 | 351 | KAPCB_CRIGR cAMP-dependent protein kinase cat... | 100 | 0.046 | 38.9 | 32 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB. | | | | | | | | | | | 463 | P00540 | 346 | MOS_HUMAN Proto-oncogene serine/threonine-pro... | 162 | 0.047 | 38.9 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 464 | Q9LEU7 | 445 | CIPK5_ARATH CBL-interacting serine/threonine-... | 87 | 0.047 | 38.9 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 465 | Q64702 | 925 | PLK4_MOUSE Serine/threonine-protein kinase PL... | 87 | 0.048 | 39.3 | 29 | 49 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; IMP:UniProtKB. | 466 | Q8N4C8 | 1332 | MINK1_HUMAN Misshapen-like kinase 1 OS=Homo s... | 99 | 0.048 | 39.3 | 24 | 46 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; IMP:UniProtKB.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB. | 467 | P29317 | 976 | EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo ... | 107 | 0.048 | 39.3 | 27 | 44 | GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0046849; P:bone remodeling; ISS:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; ISS:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IDA:UniProtKB.::GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.::GO:0043535; P:regulation of blood vessel endothelial cell migration; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; IMP:UniProtKB.::GO:0070848; P:response to growth factor stimulus; IMP:UniProtKB. | 468 | Q9JM52 | 1308 | MINK1_MOUSE Misshapen-like kinase 1 OS=Mus mu... | 99 | 0.048 | 39.3 | 24 | 46 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB. | 469 | Q1KL86 | 976 | EPHA2_MACFA Ephrin type-A receptor 2 OS=Macac... | 107 | 0.048 | 39.3 | 27 | 44 | GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046849; P:bone remodeling; ISS:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; ISS:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; ISS:UniProtKB.::GO:0070848; P:response to growth factor stimulus; ISS:UniProtKB. | 470 | P22694 | 351 | KAPCB_HUMAN cAMP-dependent protein kinase cat... | 100 | 0.049 | 38.9 | 32 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 471 | Q8AXB3 | 1302 | VGFR4_DANRE Vascular endothelial growth facto... | 103 | 0.049 | 39.3 | 30 | 44 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0048844; P:artery morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035050; P:embryonic heart tube development; IMP:ZFIN.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030878; P:thyroid gland development; IMP:ZFIN.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 472 | P51817 | 358 | PRKX_HUMAN cAMP-dependent protein kinase cata... | 104 | 0.049 | 38.9 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0043542; P:endothelial cell migration; IMP:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; IDA:UniProtKB.::GO:0060993; P:kidney morphogenesis; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; IDA:UniProtKB. | 473 | Q8QHL3 | 1327 | VGFR1_CHICK Vascular endothelial growth facto... | 82 | 0.05 | 39.3 | 33 | 50 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 474 | Q60629 | 876 | EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus m... | 85 | 0.05 | 39.3 | 28 | 47 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007411; P:axon guidance; IDA:UniProtKB.::GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IDA:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB. | 475 | P51958 | 302 | CDK1_CARAU Cyclin-dependent kinase 1 OS=Caras... | 189 | 0.051 | 38.5 | 25 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 476 | Q5R9Z7 | 970 | PLK4_PONAB Serine/threonine-protein kinase PL... | 87 | 0.051 | 39.3 | 30 | 49 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 477 | Q9Z1J2 | 792 | NEK4_MOUSE Serine/threonine-protein kinase Ne... | 173 | 0.051 | 38.9 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 478 | P38991 | 367 | IPL1_YEAST Spindle assembly checkpoint kinase... | 112 | 0.052 | 38.5 | 32 | 40 | GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD. | 479 | Q03145 | 977 | EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus m... | 190 | 0.052 | 38.9 | 24 | 41 | GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048320; P:axial mesoderm formation; IMP:MGI.::GO:0046849; P:bone remodeling; IMP:UniProtKB.::GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0070309; P:lens fiber cell morphogenesis; IDA:UniProtKB.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0021915; P:neural tube development; IMP:MGI.::GO:0030182; P:neuron differentiation; IDA:MGI.::GO:0060035; P:notochord cell development; IMP:MGI.::GO:0014028; P:notochord formation; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:UniProtKB.::GO:0030316; P:osteoclast differentiation; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045765; P:regulation of angiogenesis; IDA:UniProtKB.::GO:0043535; P:regulation of blood vessel endothelial cell migration; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; ISS:UniProtKB.::GO:0070848; P:response to growth factor stimulus; ISS:UniProtKB.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0035121; P:tail morphogenesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 480 | P05383 | 351 | KAPCB_PIG cAMP-dependent protein kinase catal... | 100 | 0.053 | 38.5 | 32 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB. | | | | | | | | | | | 481 | P05131 | 351 | KAPCB_BOVIN cAMP-dependent protein kinase cat... | 100 | 0.053 | 38.5 | 32 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | |
