rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O59671 | 263 | POF4_SCHPO Elongin-A OS=Schizosaccharomyces p... | 209 | 0.000000000000002 | 78.2 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0008023; C:transcription elongation factor complex; ISS:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase. | 2 | Q9VCP0 | 643 | ELOA1_DROME Transcription elongation factor B... | 141 | 0.00000005 | 57.8 | 28 | 50 | GO:0070449; C:elongin complex; ISS:FlyBase.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:FlyBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:UniProtKB. | 3 | Q63187 | 773 | ELOA1_RAT Transcription elongation factor B p... | 108 | 0.0000002 | 56.2 | 30 | 55 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0008023; C:transcription elongation factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; TAS:RGD. | | | | | | | | | | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB. | 4 | Q8CB77 | 773 | ELOA1_MOUSE Transcription elongation factor B... | 108 | 0.0000002 | 56.2 | 30 | 55 | GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | | 5 | Q14241 | 798 | ELOA1_HUMAN Transcription elongation factor B... | 102 | 0.0000004 | 55.1 | 31 | 54 | GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 6 | Q75E67 | 332 | ELOA1_ASHGO Elongin-A OS=Y-1056) (Yeast) (Ere... | 76 | 0.000008 | 50.4 | 36 | 57 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 7 | Q8NG57 | 546 | ELOA3_HUMAN RNA polymerase II transcription f... | 128 | 0.00001 | 50.1 | 25 | 52 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q09413 | 434 | ELOA1_CAEEL Transcription elongation factor B... | 113 | 0.00003 | 48.9 | 27 | 51 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0008023; C:transcription elongation factor complex; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB. | 9 | Q3SY89 | 546 | EA3L1_HUMAN RNA polymerase II transcription f... | 128 | 0.0001 | 47 | 24 | 52 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | A6NLF2 | 546 | EA3L2_HUMAN RNA polymerase II transcription f... | 128 | 0.0002 | 46.2 | 24 | 51 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | P53861 | 379 | ELOA1_YEAST Elongin-A OS=Saccharomyces cerevi... | 70 | 0.001 | 43.5 | 34 | 57 | GO:0031463; C:Cul3-RING ubiquitin ligase complex; IMP:SGD.::GO:0070449; C:elongin complex; IPI:SGD.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 12 | Q8IYF1 | 753 | ELOA2_HUMAN RNA polymerase II transcription f... | 114 | 0.22 | 37 | 21 | 51 | GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0032784; P:regulation of transcription elongation, DNA-dependent; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 13 | Q04721 | 2471 | NOTC2_HUMAN Neurogenic locus notch homolog pr... | 91 | 1.5 | 34.3 | 29 | 43 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003706; F:ligand-regulated transcription factor activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0046849; P:bone remodeling; IMP:UniProtKB.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; IEP:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0019827; P:stem cell maintenance; TAS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. |