| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | P58047 | 503 | C71AS_ARATH Putative cytochrome P450 71A28 OS... | 398 | 0.0000000000003 | 75.5 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 452 | Q69F95 | 466 | C85A_PHAVU Cytochrome P450 85A OS=Phaseolus v... | 443 | 0.0000000000003 | 75.1 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 453 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 441 | 0.0000000000004 | 75.1 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 454 | Q07217 | 514 | CP11A_ONCMY Cholesterol side-chain cleavage e... | 359 | 0.0000000000004 | 75.1 | 24 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 455 | P08684 | 503 | CP3A4_HUMAN Cytochrome P450 3A4 OS=Homo sapie... | 488 | 0.0000000000004 | 75.1 | 22 | 38 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0047638; F:albendazole monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0050591; F:quinine 3-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IDA:BHF-UCL.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 456 | Q1ZXC4 | 500 | C5142_DICDI Probable cytochrome P450 514A2 OS... | 466 | 0.0000000000007 | 74.3 | 21 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 457 | Q64408 | 500 | C11B1_CAVPO Cytochrome P450 11B1, mitochondri... | 242 | 0.0000000000007 | 74.3 | 29 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 458 | Q64581 | 497 | CP3AI_RAT Cytochrome P450 3A18 OS=Rattus norv... | 444 | 0.000000000001 | 73.6 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008390; F:testosterone 16-alpha-hydroxylase activity; IDA:RGD.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | | 459 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 173 | 0.000000000001 | 73.6 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 460 | P51538 | 503 | CP3A9_RAT Cytochrome P450 3A9 OS=Rattus norve... | 479 | 0.000000000001 | 73.6 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; TAS:RGD. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 461 | Q64481 | 504 | CP3AG_MOUSE Cytochrome P450 3A16 OS=Mus muscu... | 445 | 0.000000000001 | 73.6 | 21 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 462 | Q12608 | 517 | STCB_EMENI Probable sterigmatocystin biosynth... | 248 | 0.000000000001 | 73.6 | 26 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 463 | P10611 | 510 | CP4A4_RABIT Cytochrome P450 4A4 OS=Oryctolagu... | 178 | 0.000000000001 | 73.6 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 464 | Q9Y8G7 | 1066 | C505_FUSOX Bifunctional P-450:NADPH-P450 redu... | 501 | 0.000000000002 | 73.6 | 25 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:EC. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 465 | P20817 | 507 | CP4AE_RAT Cytochrome P450 4A14 OS=Rattus norv... | 173 | 0.000000000002 | 72.8 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IMP:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IMP:RGD.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IMP:RGD.::GO:0046456; P:icosanoid biosynthetic process; IMP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0043651; P:linoleic acid metabolic process; IDA:RGD. | 466 | Q64406 | 503 | CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por... | 438 | 0.000000000002 | 72.4 | 21 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 467 | P04800 | 504 | CP3A1_RAT Cytochrome P450 3A1 OS=Rattus norve... | 480 | 0.000000000003 | 72.4 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 468 | Q91WL5 | 508 | CP4CA_MOUSE Cytochrome P450 4A12A OS=Mus musc... | 173 | 0.000000000003 | 72.4 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:MGI.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. | 469 | Q940V4 | 465 | C85A2_ARATH Cytochrome P450 85A2 OS=Arabidops... | 481 | 0.000000000003 | 72.4 | 21 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:TAIR.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IDA:TAIR. | 470 | Q9VRM7 | 543 | CP307_DROME Cytochrome P450 307a1 OS=Drosophi... | 102 | 0.00001 | 51.6 | 30 | 54 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0042335; P:cuticle development; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0006697; P:ecdysone biosynthetic process; IMP:FlyBase.::GO:0048566; P:embryonic digestive tract development; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007494; P:midgut development; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase. | 471 | P17178 | 533 | CP27A_RAT Sterol 26-hydroxylase, mitochondria... | 170 | 0.000000000004 | 72 | 24 | 46 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0031073; F:cholesterol 26-hydroxylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:RGD.::GO:0006706; P:steroid catabolic process; TAS:RGD. | 472 | P51871 | 537 | CP4F6_RAT Cytochrome P450 4F6 OS=Rattus norve... | 208 | 0.000000000005 | 71.6 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD. | 473 | P24464 | 508 | CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv... | 178 | 0.000000000005 | 71.6 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 474 | P48416 | 545 | CP10_LYMST Cytochrome P450 10 OS=Lymnaea stag... | 491 | 0.000000000005 | 71.6 | 22 | 39 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 475 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 183 | 0.000000000005 | 71.6 | 25 | 46 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 476 | Q54ZM4 | 494 | C518A_DICDI Probable cytochrome P450 518A1 OS... | 479 | 0.000000000005 | 71.6 | 22 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 477 | Q02318 | 531 | CP27A_HUMAN Sterol 26-hydroxylase, mitochondr... | 198 | 0.000000000005 | 71.6 | 26 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 478 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 164 | 0.000000000006 | 71.2 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 479 | Q05JG2 | 471 | ABAH1_ORYSJ Abscisic acid 8'-hydroxylase 1 OS... | 424 | 0.000000000006 | 71.2 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 480 | Q09J79 | 471 | ABAH1_ORYSI Abscisic acid 8'-hydroxylase 1 OS... | 424 | 0.000000000006 | 71.2 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 481 | Q86W10 | 505 | CP4Z1_HUMAN Cytochrome P450 4Z1 OS=Homo sapie... | 376 | 0.000000000006 | 71.2 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
