| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P56591 | 519 | CP1A1_SHEEP Cytochrome P450 1A1 OS=Ovis aries... | 481 | 5e-41 | 159 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 32 | P48418 | 506 | C75A1_PETHY Flavonoid 3',5'-hydroxylase 1 OS=... | 504 | 5e-41 | 158 | 26 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 33 | Q64458 | 490 | CP2CT_MOUSE Cytochrome P450 2C29 OS=Mus muscu... | 499 | 6e-41 | 158 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 34 | P20814 | 490 | CP2CD_RAT Cytochrome P450 2C13, male-specific... | 445 | 6e-41 | 157 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 35 | P04798 | 512 | CP1A1_HUMAN Cytochrome P450 1A1 OS=Homo sapie... | 469 | 7e-41 | 158 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 36 | P15123 | 487 | CP2CG_RABIT Cytochrome P450 2C16 OS=Oryctolag... | 476 | 7e-41 | 157 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 37 | Q6GUQ4 | 493 | CP2E1_MACMU Cytochrome P450 2E1 OS=Macaca mul... | 488 | 8e-41 | 157 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 38 | P13108 | 500 | CP2D4_RAT Cytochrome P450 2D4 OS=Rattus norve... | 503 | 9e-41 | 157 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 39 | Q9YH64 | 521 | CP1A1_PLAFE Cytochrome P450 1A1 OS=Platichthy... | 472 | 1e-40 | 157 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 40 | P05179 | 490 | CP2C7_RAT Cytochrome P450 2C7 OS=Rattus norve... | 441 | 1e-40 | 157 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD. | 41 | P11714 | 504 | CP2D9_MOUSE Cytochrome P450 2D9 OS=Mus muscul... | 482 | 1e-40 | 157 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 42 | P11715 | 507 | CP17A_RAT Steroid 17-alpha-hydroxylase/17,20 ... | 485 | 2e-40 | 157 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IDA:RGD. | | | | | | | | | | GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0006702; P:androgen biosynthetic process; TAS:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0030728; P:ovulation; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IMP:RGD.::GO:0010034; P:response to acetate; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0017085; P:response to insecticide; IEP:RGD.::GO:0010212; P:response to ionizing radiation; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD. | 43 | O54749 | 501 | CP2J5_MOUSE Cytochrome P450 2J5 OS=Mus muscul... | 485 | 2e-40 | 156 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 44 | Q5KQT7 | 517 | CP1A1_FELCA Cytochrome P450 1A1 OS=Felis catu... | 487 | 2e-40 | 156 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 45 | O73853 | 514 | CP17A_ICTPU Steroid 17-alpha-hydroxylase/17,2... | 443 | 2e-40 | 156 | 25 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 46 | P79760 | 530 | CP1A4_CHICK Cytochrome P450 1A4 OS=Gallus gal... | 453 | 2e-40 | 156 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 47 | Q0IIF9 | 543 | CP2U1_BOVIN Cytochrome P450 2U1 OS=Bos taurus... | 508 | 3e-40 | 156 | 22 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 48 | Q92100 | 521 | CP1A1_PLEPL Cytochrome P450 1A1 OS=Pleuronect... | 441 | 4e-40 | 156 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 49 | P56656 | 490 | CP239_MOUSE Cytochrome P450 2C39 OS=Mus muscu... | 485 | 5e-40 | 155 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 50 | P27786 | 507 | CP17A_MOUSE Steroid 17-alpha-hydroxylase/17,2... | 482 | 5e-40 | 155 | 26 | 44 | GO:0030424; C:axon; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IDA:MGI. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; IDA:MGI. | 51 | P05177 | 515 | CP1A2_HUMAN Cytochrome P450 1A2 OS=Homo sapie... | 480 | 5e-40 | 155 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0032451; F:demethylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009820; P:alkaloid metabolic process; IDA:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0032259; P:methylation; TAS:Reactome.::GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0071615; P:oxidative deethylation; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0009403; P:toxin biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 52 | P12791 | 500 | CP2BA_MOUSE Cytochrome P450 2B10 OS=Mus muscu... | 451 | 5e-40 | 155 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 53 | Q6VVX0 | 501 | CP2R1_HUMAN Vitamin D 25-hydroxylase OS=Homo ... | 403 | 7e-40 | 155 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042359; P:vitamin D metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 54 | P05181 | 493 | CP2E1_HUMAN Cytochrome P450 2E1 OS=Homo sapie... | 475 | 9e-40 | 154 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 55 | P00184 | 524 | CP1A1_MOUSE Cytochrome P450 1A1 OS=Mus muscul... | 445 | 9e-40 | 155 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009308; P:amine metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI. | 56 | Q64680 | 500 | CP2DI_RAT Cytochrome P450 2D18 OS=Rattus norv... | 503 | 1e-39 | 154 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0008391; F:arachidonic acid monooxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IMP:RGD. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0042416; P:dopamine biosynthetic process; IDA:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0010033; P:response to organic substance; IEP:RGD. | 57 | P52786 | 501 | CP2J1_RABIT Cytochrome P450 2J1 OS=Oryctolagu... | 485 | 2e-39 | 154 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 58 | P56590 | 524 | CP1A1_CANFA Cytochrome P450 1A1 OS=Canis fami... | 510 | 2e-39 | 154 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 59 | Q08078 | 490 | CP2CP_MESAU Cytochrome P450 2C25 OS=Mesocrice... | 469 | 2e-39 | 153 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 60 | O42457 | 521 | CP1A1_SPAAU Cytochrome P450 1A1 OS=Sparus aur... | 468 | 3e-39 | 153 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 61 | P56655 | 490 | CP238_MOUSE Cytochrome P450 2C38 OS=Mus muscu... | 442 | 4e-39 | 152 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
