rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | B5XMZ4 | 323 | GHRB_KLEP3 Glyoxylate/hydroxypyruvate reducta... | 271 | 3e-28 | 115 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 92 | A6TFG7 | 323 | GHRB_KLEP7 Glyoxylate/hydroxypyruvate reducta... | 271 | 4e-28 | 115 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 93 | O04130 | 624 | SERA_ARATH D-3-phosphoglycerate dehydrogenase... | 306 | 1e-27 | 117 | 29 | 49 | GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 94 | P58000 | 323 | GHRB_ENTAG Glyoxylate/hydroxypyruvate reducta... | 244 | 3e-27 | 113 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 95 | Q61753 | 533 | SERA_MOUSE D-3-phosphoglycerate dehydrogenase... | 256 | 5e-27 | 114 | 32 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:MGI. | | | | | | | | | | GO:0022402; P:cell cycle process; IMP:MGI.::GO:0009448; P:gamma-aminobutyric acid metabolic process; IMP:MGI.::GO:0021782; P:glial cell development; IMP:MGI.::GO:0006541; P:glutamine metabolic process; IMP:MGI.::GO:0006544; P:glycine metabolic process; IMP:MGI.::GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.::GO:0021915; P:neural tube development; IMP:MGI.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI.::GO:0019530; P:taurine metabolic process; IMP:MGI.::GO:0006566; P:threonine metabolic process; IMP:MGI. | 96 | A5GFY8 | 533 | SERA_PIG D-3-phosphoglycerate dehydrogenase O... | 292 | 5e-27 | 114 | 31 | 48 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 97 | O43175 | 533 | SERA_HUMAN D-3-phosphoglycerate dehydrogenase... | 256 | 9e-27 | 113 | 32 | 51 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:Reactome. | | | | | | | | | | GO:0007420; P:brain development; TAS:ProtInc.::GO:0006564; P:L-serine biosynthetic process; TAS:Reactome. | 98 | A5A6P1 | 533 | SERA_PANTR D-3-phosphoglycerate dehydrogenase... | 256 | 1e-26 | 113 | 32 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 99 | Q9W758 | 437 | CTBP2_XENLA C-terminal-binding protein 2 OS=X... | 238 | 1e-26 | 112 | 32 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 100 | O08651 | 533 | SERA_RAT D-3-phosphoglycerate dehydrogenase O... | 256 | 1e-26 | 113 | 31 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 101 | O46036 | 476 | CTBP_DROME C-terminal-binding protein OS=Dros... | 301 | 2e-26 | 112 | 31 | 46 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IDA:FlyBase.::GO:0003714; F:transcription corepressor activity; IDA:FlyBase. | | | | | | | | | | GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:FlyBase. | 102 | Q60HD7 | 533 | SERA_MACFA D-3-phosphoglycerate dehydrogenase... | 256 | 2e-26 | 113 | 31 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 103 | O58320 | 334 | GYAR_PYRHO Glyoxylate reductase OS=NBRC 10013... | 262 | 3e-26 | 110 | 36 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 104 | Q5HLU4 | 317 | Y1888_STAEQ Putative 2-hydroxyacid dehydrogen... | 236 | 3e-26 | 110 | 35 | 53 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 105 | Q6DB24 | 320 | GHRB_ERWCT Glyoxylate/hydroxypyruvate reducta... | 272 | 3e-26 | 110 | 34 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 106 | Q8CNB8 | 317 | Y1879_STAES Putative 2-hydroxyacid dehydrogen... | 236 | 5e-26 | 109 | 35 | 53 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 107 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 323 | 5e-26 | 110 | 29 | 46 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 108 | Q5EAD2 | 533 | SERA_BOVIN D-3-phosphoglycerate dehydrogenase... | 256 | 5e-26 | 111 | 31 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 109 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 323 | 6e-26 | 110 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 110 | Q9YHU0 | 440 | CTBP1_XENLA C-terminal-binding protein 1 OS=X... | 323 | 1e-25 | 109 | 29 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 111 | O94574 | 340 | YGDH_SCHPO Putative 2-hydroxyacid dehydrogena... | 241 | 2e-25 | 108 | 30 | 51 | GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; ISS:PomBase.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0009436; P:glyoxylate catabolic process; ISS:PomBase.::GO:0006111; P:regulation of gluconeogenesis; IC:PomBase. | 112 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 323 | 2e-25 | 108 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 113 | Q5R7M2 | 533 | SERA_PONAB D-3-phosphoglycerate dehydrogenase... | 256 | 3e-25 | 109 | 31 | 50 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 114 | Q91Z53 | 328 | GRHPR_MOUSE Glyoxylate reductase/hydroxypyruv... | 276 | 6e-25 | 106 | 32 | 49 | | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 115 | Q9EQH5 | 445 | CTBP2_RAT C-terminal-binding protein 2 OS=Rat... | 256 | 7e-25 | 107 | 32 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 116 | P56546 | 445 | CTBP2_MOUSE C-terminal-binding protein 2 OS=M... | 256 | 7e-25 | 107 | 32 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 117 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 259 | 8e-25 | 107 | 32 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 118 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 259 | 1e-24 | 106 | 32 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 119 | P87228 | 466 | SERA_SCHPO Putative D-3-phosphoglycerate dehy... | 244 | 3e-24 | 105 | 32 | 51 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; ISS:PomBase. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; ISS:PomBase. | 120 | P40054 | 469 | SERA_YEAST D-3-phosphoglycerate dehydrogenase... | 234 | 4e-23 | 102 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 121 | P40510 | 469 | SER33_YEAST D-3-phosphoglycerate dehydrogenas... | 234 | 5e-23 | 102 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. |