rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P56518 | 576 | HDAC1_STRPU Histone deacetylase 1 OS=Strongyl... | 576 | 0 | 599 | 53 | 69 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q94517 | 521 | HDAC1_DROME Histone deacetylase Rpd3 OS=Droso... | 435 | 0 | 591 | 62 | 80 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IPI:FlyBase.::GO:0005705; C:polytene chromosome interband; IDA:FlyBase.::GO:0016580; C:Sin3 complex; NAS:FlyBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IPI:FlyBase.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0006342; P:chromatin silencing; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0050771; P:negative regulation of axonogenesis; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0022904; P:respiratory electron transport chain; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 3 | P32561 | 433 | RPD3_YEAST Histone deacetylase RPD3 OS=Saccha... | 417 | 0 | 587 | 65 | 80 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.::GO:0070211; C:Snt2C complex; IDA:SGD. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; IMP:SGD.::GO:0003714; F:transcription corepressor activity; IMP:SGD. | | | | | | | | | | GO:0070932; P:histone H3 deacetylation; IMP:SGD.::GO:0070933; P:histone H4 deacetylation; IMP:SGD.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:SGD.::GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IDA:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IPI:SGD.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD. | 4 | Q92769 | 488 | HDAC2_HUMAN Histone deacetylase 2 OS=Homo sap... | 445 | 0 | 586 | 61 | 80 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0032967; P:positive regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | P56517 | 480 | HDAC1_CHICK Histone deacetylase 1 OS=Gallus g... | 443 | 0 | 585 | 60 | 80 | | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | | 6 | P70288 | 488 | HDAC2_MOUSE Histone deacetylase 2 OS=Mus musc... | 445 | 0 | 584 | 61 | 80 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005657; C:replication fork; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.::GO:0017053; C:transcriptional repressor complex; IPI:MGI. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; IDA:MGI.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0010977; P:negative regulation of neuron projection development; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | O42227 | 480 | HDA1B_XENLA Probable histone deacetylase 1-B ... | 434 | 0 | 575 | 60 | 81 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | P56519 | 488 | HDAC2_CHICK Histone deacetylase 2 OS=Gallus g... | 445 | 0 | 565 | 60 | 78 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | O09106 | 482 | HDAC1_MOUSE Histone deacetylase 1 OS=Mus musc... | 393 | 0 | 563 | 63 | 82 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000792; C:heterochromatin; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016581; C:NuRD complex; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0042733; P:embryonic digit morphogenesis; IGI:BHF-UCL.::GO:0007492; P:endoderm development; IDA:MGI.::GO:0009913; P:epidermal cell differentiation; IGI:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; IGI:BHF-UCL.::GO:0061198; P:fungiform papilla formation; IGI:BHF-UCL.::GO:0060789; P:hair follicle placode formation; IGI:BHF-UCL.::GO:0021766; P:hippocampus development; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0030182; P:neuron differentiation; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q4QQW4 | 482 | HDAC1_RAT Histone deacetylase 1 OS=Rattus nor... | 393 | 0 | 563 | 63 | 82 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q32PJ8 | 482 | HDAC1_BOVIN Histone deacetylase 1 OS=Bos taur... | 393 | 0 | 563 | 63 | 82 | | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | | 12 | Q5RAG0 | 482 | HDAC1_PONAB Histone deacetylase 1 OS=Pongo ab... | 393 | 0 | 563 | 63 | 82 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q13547 | 482 | HDAC1_HUMAN Histone deacetylase 1 OS=Homo sap... | 393 | 0 | 563 | 63 | 82 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016581; C:NuRD complex; IDA:UniProtKB.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006338; P:chromatin remodeling; IC:BHF-UCL.::GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.::GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.::GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.::GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0000278; P:mitotic cell cycle; TAS:Reactome.::GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL. | 14 | O17695 | 461 | HDA1_CAEEL Histone deacetylase 1 OS=Caenorhab... | 444 | 0 | 554 | 57 | 77 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043073; C:germ cell nucleus; IDA:WormBase.::GO:0000118; C:histone deacetylase complex; IPI:WormBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0048557; P:embryonic digestive tract morphogenesis; IGI:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:WormBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; IGI:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0045595; P:regulation of cell differentiation; IGI:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q91695 | 480 | HDA1A_XENLA Probable histone deacetylase 1-A ... | 436 | 0 | 552 | 60 | 79 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q55FN5 | 495 | HDA11_DICDI Type-1 histone deacetylase 1 OS=D... | 439 | 0 | 536 | 56 | 78 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | O59702 | 405 | CLR6_SCHPO Histone deacetylase clr6 OS=Schizo... | 381 | 0 | 531 | 62 | 79 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0033698; C:Rpd3L complex; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0032221; C:Rpd3S complex; IDA:PomBase. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; TAS:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; NAS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | P56520 | 428 | HDAC3_CHICK Histone deacetylase 3 OS=Gallus g... | 404 | 7e-177 | 514 | 59 | 77 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q4SFA0 | 428 | HDAC3_TETNG Histone deacetylase 3 OS=nigrovir... | 434 | 2e-176 | 513 | 56 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q6P6W3 | 428 | HDAC3_RAT Histone deacetylase 3 OS=Rattus nor... | 431 | 2e-176 | 513 | 56 | 74 | GO:0000785; C:chromatin; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0070932; P:histone H3 deacetylation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | O15379 | 428 | HDAC3_HUMAN Histone deacetylase 3 OS=Homo sap... | 431 | 2e-176 | 513 | 56 | 74 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.::GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q28DV3 | 428 | HDAC3_XENTR Histone deacetylase 3 OS=Xenopus ... | 434 | 3e-176 | 512 | 55 | 75 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q9FML2 | 471 | HDA6_ARATH Histone deacetylase 6 OS=Arabidops... | 405 | 4e-176 | 514 | 59 | 78 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016441; P:posttranscriptional gene silencing; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0010431; P:seed maturation; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR. | 24 | O88895 | 424 | HDAC3_MOUSE Histone deacetylase 3 OS=Mus musc... | 406 | 8e-176 | 511 | 58 | 76 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | Q6IRL9 | 428 | HDAC3_XENLA Histone deacetylase 3 OS=Xenopus ... | 434 | 8e-176 | 511 | 56 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q5RB76 | 428 | HDAC3_PONAB Histone deacetylase 3 OS=Pongo ab... | 431 | 2e-175 | 510 | 56 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q8H0W2 | 426 | HDA9_ARATH Histone deacetylase 9 OS=Arabidops... | 427 | 2e-174 | 508 | 55 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q803C3 | 428 | HDAC3_DANRE Histone deacetylase 3 OS=Danio re... | 432 | 4e-174 | 507 | 55 | 73 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q55BW2 | 422 | HDA12_DICDI Histone deacetylase B OS=Dictyost... | 435 | 2e-169 | 494 | 53 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:dictyBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | O22446 | 501 | HDA19_ARATH Histone deacetylase 19 OS=Arabido... | 401 | 2e-168 | 495 | 58 | 77 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0016573; P:histone acetylation; IDA:TAIR.::GO:0009861; P:jasmonic acid and ethylene-dependent systemic resistance; IMP:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009405; P:pathogenesis; IMP:TAIR.::GO:2000026; P:regulation of multicellular organismal development; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | P56521 | 513 | HDA19_MAIZE Probable histone deacetylase 19 O... | 378 | 6e-165 | 487 | 60 | 78 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |